41results about "Ear implants" patented technology

The systems and methods can be employed for transtympanic access to the middle ear for delivery of therapeutic formulations or implant devices to target locations under direct visualization. The systems and methods can also be used to improve access and visualization for various otologic surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair, and ossicular chain repair.

The present application relates to the technical field of ossicle prosthesis. An adaptive base plate ossicle prosthesis comprises a base plate structure for connecting with a tympanic membrane and a stem, the base plate structure is fixedly connected with the stem, the base plate structure comprises a connecting part for connecting with the stem and at least six adaptive adjusting branches; all the adaptive adjusting branches are distributed at equal interval angles in a circumferential direction, and the inner sides of all the adaptive adjusting branches are fixedly connected with the outer side of the connecting part; gaps exist between all the adaptive adjusting branches. The present application is convenient for meeting the structure of the tympanic membrane and improving the fitting stability with the tympanic membrane through the adaptive adjusting branches. The independent adaptive adjusting branches will deform according to different regions of the tympanic membrane, so as to adapt to the structure of the tympanic membrane.

The invention proposes to construct a one-piece, pincer-like ossicular prosthesis (1) from sheet metal, with two congruent clamps (3) that can be opened and closed by means of a two-part head element (2), the head parts (4) of which function as pincer handles. The ossicular prosthesis (1) can be clamped onto an ossicle without exerting any force on the ossicle.

The present invention relates to a device with a structured coating for adhesion to rough surfaces, particularly biological surfaces, comprising a carrier layer (101) on which a plurality of protrusions are arranged, each of the protrusions comprising at least one stem having an end face facing away from the surface, and a further layer (104) arranged on at least the end faces, said layer having a lower modulus of elasticity and in the form of a film interconnecting the protrusions. The film may be in the form of a removable film.

The subject of the invention is a middle ear prosthesis (1), in particular of the middle ear conductive chain, comprising a first spring element (2) constituting a spring of at least one coil, having a length Lm in the range from 0.2 mm to 10 mm, and possibly a second spring element (3) constituting a spring of at least one coil, having a length Lk in the range from 0.1 mm to 4 mm, wherein the first spring element (2) and the second spring element (3) are made of wire of a material having a Young's modulus E in the range from 7 · 1010 N / m2 to 11.4.1010 N / m2, a density p in the range from 4.103 kg / m3 to 20. 103 kg / m3, a Poisson's ratio v in the range from 0.34 to 0.44, wherein the first spring element (2) is connected to the second spring element (3) in such a way that the rotational symmetry axis of the first spring element (2) is placed at an angle α-ι with respect to the rotational symmetry axis of the second spring element (3), included in the range from 5° to 160°.

The present invention relates to the preparation of a membrane for use in the repair of the middle ear including perforations and damage to the tympanic membrane. More particularly, the invention provides for compositions and methods for preparing silk fibroin biocompatible polyurethane membranes using a solvent, which have improved biodegradation, mechanical and vibroacoustic properties.

An improved total ossicular replacement prosthesis (TORR) for the reconstruction of the ossicular chain provides, in combination: a head (C) which is formed by a single cartilaginous block: a synthetic stem (A) of cylindrical shape which is provided, on both sides, with a respective blunt tip (Al, A4); a cartilaginous base (B) having the same thickness as the head (C) but with a smaller surface. Said improved TORR is configured in such a way as to be able to position, respectively, said head (C) under the tympanic membrane (D) and said base (B) above the plate (E) of the stapes (s); thus obtaining that during the healing process, the perichondrium of the head (C) is welded to the tympanic membrane (D) and the perichondrium of the base (B) is welded to the mucosa of the plate (E)

A vestibular electrode fixation methodology and device for implantation in a subject is provided. The methodology includes making an opening through both a stapedial footplate and the oval window of the subject, through which the electrode is inserted. The electrode may pass through a flange which contacts the posterior and anterior crus, securely fixing the electrode in a predetermined position so as to stimulate the sensory epithelia in the vestibule. The flange may sit on the stapedial footplate.

An ear implant selection kit is described including a set of semi-transparent or transparent contour templates, a separate set of gradation templates, and a set of three-dimensional ear implant models, all of which may be used to select an ear implant out of a set of implants that best matches the appearance of a contralateral ear of an individual. Related ear implant systems and methods are also described.

The disclosure relates to winged graft devices, methods of manufacture, and methods of use to repair, e.g., repair perforations, in tympanic membranes, or to augment defective tympanic membranes.

Devices, systems, and methods can be employed to facilitate indirect viewing of a cavity, such as, but not limited to, a middle ear space. Some embodiments have uses such as, but not limited to, facilitating visualization and surgery in the outer ear, middle ear, and / or inner ear, in order to diagnose and / or treat conditions, including but not limited to hearing loss and other ear conditions. In particular implementations, a surgical microscope is used in conjunction with a reversing lens and a distal lens. In some cases, the distal lens traverses a membrane or septum, such as, but not limited to, the tympanic membrane. In some embodiments, the distal lens can be an assembly that combines two or more lenses. For example, in some cases, wide angle lenses, zoom lenses, other variously shaped lenses, and / or prisms can be used in the distal lens.

The invention proposes providing a partially annular fastening element (2) of an ossicular prosthesis (1) (so-called "stapes prosthesis") for a human middle ear with a window (6) in one piece, which window extends in a circumferential direction of the fastening element (2) and in which a curved spring tab (8) is arranged, which is one piece with the fastening element (2) and projects in an arcuate manner with an inward incline beyond an inner circumference of the fastening element (2). The spring tab (8), which bears against the ossicle with prestress, ensures a play-free fit of the ossicular prosthesis (1) on an ossicle.

The present invention discloses an artificial auricle material with a dual framework of vascularization and chondrogenicity, and a preparation method thereof. The method comprises: 1) performing 3D modeling as needed to obtain an artificial auricle scaffold model with a large pore, and pre-setting a vascularization differentiation framework on the scaffold; 2) using multi-material multi-nozzle light-curing 3D printing technology, simultaneously printing the artificial auricle scaffold with a GelMA solution and printing a vascularization framework within the scaffold using a GelMA solution containing mesenchymal stem cells (MSCs); and culturing the vascularization differentiation to obtain an intermediate-form artificial auricle with the vascularization framework; 3) combining a multiple-immersion light-curing method, introducing a ColMA solution containing MSCs into the pores of the intermediate-form artificial auricle; and culturing the chondrogenic differentiation to obtain an artificial auricle material with both a vascularization and chondrogenicity framework. The simultaneous provision of vascularization and chondrogenicity frameworks within the scaffold provides a design paradigm for an artificial auricle with complete physiological functions.

Devices, systems, and methods can be used to facilitate performing procedures in the outer, middle, and / or inner ear in order to diagnose and / or treat diseases, including but not limited to hearing loss and other ear diseases. For example, devices, systems, and methods are described herein that include instruments and techniques to minimize invasiveness and / or enhance the efficacy of procedures performed in the outer, middle, and / or inner ear space, such as, for example, mastoidectomy, tympanoplasty, cholesteatoma treatment, otosclerosis treatment, and Eustachian tube treatment.

A surgical cutting device (10) for otology for producing a thin tissue or cartilage disc (18') from the patient's own tissue (18) for otological applications, comprising an elongated device body (11) aligned along a longitudinal axis (z), which includes at a first end a handle-like grip (12) and at the opposite second end a cutting head (13) with a cutting blade (14) having a blade body (14') with a sharp cutting edge (14"), is characterized in that the cutting blade is arranged within a cutting window (15) which is open throughout in a direction (x') transverse to the direction of the longitudinal axis z; that the cutting blade is positioned in the cutting window such that its sharp cutting edge is aligned parallel to a transverse axis (y) which is perpendicular to the longitudinal axis and oblique to the direction x';that the sharp cutting edge is positioned axially away from the blade body in the direction of the longitudinal axis towards the handle-like grip; and that the cutting blade is either rigidly or movably connected to the device body around the transverse axis. This allows the cutting process to be carried out simply and safely, resulting in particularly uniform cutting results with high-quality cutting products, especially corticomedium or tissue plates with a defined, predeterminable layer thickness.

The invention relates to a device having a structured coating for adhesion to rough, in particular biological surfaces, comprising a carrier layer (101), wherein a plurality of elevations are provided on the carrier layer (101), which in each case comprise at least one stem having an end face facing away from the surface, and wherein at least on the end face a further layer (104) is arranged, which has a lower modulus of elasticity and is designed as a film connecting the elevations. The film can also be detachable.

An auditory ossicular prosthesis (20) with a first fastening element (21) designed as a head plate for contact with the eardrum, a second fastening element (22) for mechanical connection to a link of the auditory ossicular chain or to the inner ear, and a shaft-shaped connecting element (24) connecting the two fastening elements to one another in a sound-conducting manner along a longitudinal axis, wherein the first fastening element has in its center a through-bore (25) that can be narrowed for fixation and for receiving the connecting element, is characterized in that the connecting element projects through the through-bore onto the side of the first fastening element opposite the second fastening element and carries, at its free end opposite the second fastening element, a third fastening element (23) that is designed for connection to a link of the auditory ossicular chain or to the inner ear,and that the connecting element is designed in its two areas adjacent to the through-hole so that it can be easily separated above or below the first fastening element. This package offers the middle ear surgeon a simple and quick option to select from a range of different prosthesis types immediately before inserting a selected prosthesis into the patient's middle ear.

The application discloses a prosthesis for ossicular chain reconstruction, which is used for replacing or bridging at least one element of an ossicular chain of a human being and comprises a first coupling unit arranged at a proximal end and used for matching with a tympanic membrane and receiving vibration brought by sound, a second coupling unit arranged at a distal end and mechanically connected with a stapes, and a connecting piece connected between the first coupling unit and the second coupling unit and used for transmitting vibration energy; the connecting piece is made of a material with deformation ability, so that the connecting piece can be reciprocally bent to adjust an angle; and the first coupling unit is a spiral coil disc. The application has the advantages that the spiral coil disc is used as the first coupling unit, the spiral structure of the spiral coil disc is easy to adjust in shape according to requirements during an operation, and the application is reduced in displacement and out of position; in addition, the connecting piece is made of a material with deformation ability, so that the connecting piece is easy to adjust during the operation, the prosthesis does not need to be additionally replaced or cut, the operation time is reduced, and the prosthesis can keep a continuous tension, so that the risk of displacement and out of position of the prosthesis is reduced.

Prosthetic tegmen plates are provided. The prosthetic tegmen plates include a body that defines at least one engagement surface that substantially conforms to a region of a corresponding surface of a subject's temporal bone having a tegmen defect. The prosthetic tegmen plates are configured to cover the tegmen defect. Methods for manufacturing prosthetic tegmen plates by additive manufacturing and surgically implanting prosthetic tegmen plates are also provided.

Systems and methods can be employed to facilitate access and surgery in the external, middle, and inner ear for the diagnosis or treatment of ear conditions including, but not limited to, hearing loss and excess earwax. In some examples, the systems and methods include instruments and techniques that facilitate trans-tympanic or trans-fibroannular access to the middle ear. The systems and methods can also be used to improve the accessibility of various otologic procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair, and ossicular chain repair.

A system for partial ossicular replacement with controllable stapedial engaging function is described; a respective process of manufacturing a partial ossicular replacement prosthesis with controllable stapedial engaging function and a partial ossicular replacement prosthesis are further described; the system comprises: a partial ossicular replacement prosthesis comprising a stapedial part and a tympanic part, an applicator device comprising a handpiece, an essentially planar static face, an elongated essentially cylindrically shaped plunger; the process comprises: providing a preform of at least stapedial part, forming a plurality of elongated cuts, shaping a centrical portion, shaping a distal portion; the partial ossicular replacement prosthesis comprises a stapedial part and a tympanic part.

Devices, systems, and methods for facilitating performing procedures in the outer, middle, and inner ear may be used to diagnose and / or treat disorders, including, but not limited to, hearing loss and other ear disorders. For example, this document describes devices, systems, and methods, including instruments and techniques, that minimize the invasiveness and / or enhance the effectiveness of procedures performed in the outer, middle, and / or inner ear spaces, such as mastoidectomy, tympanoplasty, cholesteatoma treatment, otosclerosis treatment, and Eustachian tube treatment.

A device, including a tissue interface portion configured for securement to tissue of and / or proximate an inner ear of a human and provide a passage from outside the inner ear to inside the inner ear, wherein the tissue interface portion has a longitudinal axis, a surface of the tissue interfacing portion that directly interfaces with tissue and / or indirectly interfaces with tissue when the tissue interface portion is secured to the tissue is more normal than parallel to the longitudinal axis, and the surface is located at a distal section of the tissue interface portion.

An ossicular prosthesis (10) comprising a first and second attachment element (11, 12), a connecting element (13), and bar elements (14) is characterized in that the bar elements open directly into coupling areas (15) of the first attachment element within the plane of the head plate and are movably but permanently connected to them; that all bar elements are movably and, in operation, firmly but detachably connected to a coupling element (16), wherein the coupling element is, in turn, rigidly connected at its other end to either the first or the second attachment element; that the bar elements together with the coupling element form the connecting element; that, in situ in the middle ear, when a force is applied parallel to the longitudinal axis (z), the bar elements are section by section radially spread away from the longitudinal axis, thereby shortening the axial functional length of the prosthesis, while when a force is applied antiparallel to it, they are increased.and that the bridge elements maintain their set radial position in situ without the application of any force. This allows for length adjustment in situ with the prosthesis already in place, even from above, ensuring uniform and symmetrical elongation of the prosthesis and enabling its use even with partial dentures with low axial height and / or short functional length.

The invention discloses an artificial ossicular implanting device which comprises a fixed forceps handle, a movable forceps handle, an outer tube and an ejector pin. The movable plier handle is hinged to the fixed plier handle, the outer pipe is installed at the head end of the fixed plier handle, the ejector pin penetrates through the outer pipe, the tail end of the ejector pin is connected to the head end of the movable plier handle, and handheld parts are arranged at the tail ends of the movable plier handle and the fixed plier handle; the ejector pin is driven to move in the outer pipe based on opening or retracting of the movable clamp handle; the head end of the outer tube is provided with a notch used for containing any grabbing hole of a disc of the artificial ossicular, and the movable clamp handle drives the ejector pin to stretch out and penetrate through any grabbing hole of the disc so that the artificial ossicular can be fixed to the head end of the outer tube. The artificial auditory ossicle implanting device only penetrates through one grabbing hole of the artificial auditory ossicle to clamp the artificial auditory ossicle, so that other grabbing holes (the grabbing holes serve as windows of a doctor in the operation process) are exposed, the operation view angle is not affected, and operation operation is facilitated.

Certain embodiments described herein provide a method of performing an otological surgical procedure including surgically accessing a middle ear, injecting a perfluorocarbon liquid into the middle ear, and suctioning the isolated blood from the middle ear without removing the perfluorocarbon liquid. The perfluorocarbon liquid is immiscible with blood for isolating blood in the middle ear from the perfluorocarbon liquid. In certain embodiments, the perfluorocarbon liquid has a specific gravity greater than blood to apply positive pressure to surrounding tissues. In certain embodiments, the method includes suctioning the perfluorocarbon liquid from the middle ear after the isolated blood is removed.

Intratympanic injection of therapeutic agents into the inner ear can be used to treat conditions such as hearing loss. One or more stabilizer devices defining a working channel can be temporarily implanted into the tympanic membrane. Specialized instruments, such as endoscopes, forceps, and injection instruments, can be passed through the working channel of the stabilizer device to access the inner ear, where administration of the therapeutic agent can occur. The stabilizer device is then removed from the tympanic membrane, and the tympanic membrane can heal, typically without the need for suturing.

An improved TORP for the reconstruction of the ossicular chain provides, in combination: a head (C) which is formed by a single cartilaginous block:—a synthetic stem (A) of cylindrical shape which is provided, on both sides, with a respective blunt tip (A1, A2); a cartilaginous base (B) having the same thickness as the head (C) but with a smaller surface.Said improved TORP is configured in such a way as to be able to position, respectively, said head (c) under the tympanic membrane (D) and said base (B) above the plate (E) of the stapes (s); thus obtaining that during the healing process, the perichondrium of the head (c) is welded to the tympanic membrane (D) and the perichondrium of the base (B) is welded to the mucosa of the plate (E).

Disclosed is a method of treating a chronic tympanic perforation with a PCL patch tissue regeneration scaffold comprising preparing solution by adding polycaprolactone (PCL) and an acid to an organic solvent; preparing an electrospinning solution by adding a growth factor to the solution and stirring; collecting nanofibers arranged in a spindle shape on a collector by connecting the electrospinning solution prepared to a syringe pump and operating the electrospinning device; and administering the PCL patch tissue regeneration scaffold to a subject.