The present invention provides a medical liquid administration apparatus and administration method that are particularly apt for intravenous (IV) applications. More particularly, the administration apparatus and method may be employed in conjunction with the administration of liquid medication and one or more flush solutions from multi-dose sources, wherein fluid interconnections between at least one flush solution source and the administration apparatus may be established a single time at the outset of a given procedure. The administration apparatus may include a valve having a control member selectively positionable to provide any selected one of a plurality of closed flow paths through the valve, and a syringe interconnected to the control member for clockwise / counterclockwise co-rotation therewith (e.g. to establish the selected flow path). The valve may include a valve housing have a plurality of ports, wherein in one arrangement at least two of the ports have corresponding center axes lying in offset first and second planes. Correspondingly, the control member may include an internal passageway extending between a plurality of apertures, wherein at least two of the apertures have center axes lying in said offset first and second planes. By selectively rotating the control member, different fluid paths may be established between different ones of the valve housing ports, thereby facilitating closed-path passage of a liquid medication and one or more flush solutions therethrough. In particular, the flush solution(s) and liquid medication may be passed sequentially into the interconnected syringe for subsequent manual administration by medical personnel.