Chinese medicinal composition for improving bone marrow depression caused by radiotherapy and chemotherapy and preparation method thereof

A technology for bone marrow suppression and composition, applied in the field of traditional Chinese medicine compositions, can solve the problems of infection, anemia and hemorrhage, insignificant treatment effect, slow whitening effect, etc., and achieves improvement of bone marrow suppression response, improved compliance, and less toxic and side effects. Effect

Inactive Publication Date: 2010-12-15
WEST CHINA HOSPITAL SICHUAN UNIV
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AI Technical Summary

Problems solved by technology

[0003] Bone marrow suppression is the most common side effect of tumor radiotherapy and chemotherapy. It is mainly caused by the decrease of white blood cells. Red blood cells and platelets can also decrease to varying degrees. Severe cases can cause infection, anemia and hemorrhage...

Method used

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  • Chinese medicinal composition for improving bone marrow depression caused by radiotherapy and chemotherapy and preparation method thereof
  • Chinese medicinal composition for improving bone marrow depression caused by radiotherapy and chemotherapy and preparation method thereof

Examples

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Effect test

Embodiment 1-8

[0030] Traditional Chinese medicine compositions 1-8 for improving myelosuppression caused by radiotherapy and chemotherapy were prepared according to the ratio of raw materials and dosage forms of each example listed in the following Table 1.

[0031] Raw material weight ratio and dosage form (unit: g) of each embodiment of table 1

[0032]

[0033] The above-mentioned pharmaceutical compositions 1-8 are all prepared by a method comprising the following main steps:

[0034] (1) Pulverize Ziheche and Panax notoginseng into fine powder, set aside;

[0035] (2) Combine drynaria rhizome, raw sun-dried ginseng and roasted licorice, add water to decoct and extract, filter, concentrate the filtrate, add tortoise shell glue, deer horn glue, donkey-hide gelatin, purple river carnation fine powder, notoginseng fine powder, mix well, Drying to obtain mixed extracts;

[0036] (3) Take the mixed extract obtained in step (2), add auxiliary materials, and prepare the medicines in the o...

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Abstract

The invention discloses a Chinese medicinal composition for improving bone marrow depression caused by radiotherapy and chemotherapy. The Chinese medicinal composition is prepared from the following raw materials in part by weight: 9 to 15 parts of tortoise-plastron glue, 9 to 15 parts of deerhorn glue, 9 to 15 parts of donkey-hide gelatin, 9 to 15 parts of dried human placenta, 9 to 15 parts of drynaria rhizome, 7 to 13 parts of pseudo-ginseng root, 9 to 15 parts of suncured ginseng and 1 to 6 parts of fried licorice root. The Chinese medicinal composition has the effects of tonifying qi, enriching blood, tonifying kidney and replenishing essence, is used for improving the bone marrow depression caused by the radiotherapy and chemotherapy and symptoms such as weakness, palpitation, shortness of breath, pale face, pale tongue, white fur, weak pulse and the like caused by hypocytosis, can effectively improve the bone marrow depression reaction caused by the radiotherapy and chemotherapy and improve the compliance of tumor patients with radiotherapy and chemotherapy. The invention also discloses a preparation method of the Chinese medicinal composition.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine compound preparation for improving myelosuppression caused by radiotherapy and chemotherapy. Background technique [0002] Under normal circumstances, the proliferation, maturation and release of cells in the bone marrow are in a relatively constant state with the aging death, destruction and discharge of granulocytes in the peripheral blood. Certain tumors disrupt this balance during their treatment, resulting in leukopenia or even pancytopenia. The suppression of bone marrow by various radiations is more common in tumor radiation therapy and after radiation therapy. Radiation can not only suppress bone marrow, but also directly kill granulocytes or cause chromosomal changes, and the changes in microcirculation are often not restored within a considerable period of time. Chemotherapy drugs with radiosensitization effects, such as DNR ...

Claims

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Application Information

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IPC IPC(8): A61K36/484A61P19/08A61P7/06A61K35/32A61K35/36A61K35/50A61K35/56A61K35/586
Inventor 张瑞明
Owner WEST CHINA HOSPITAL SICHUAN UNIV
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