Traditional Chinese medicine preparation for treating immune thrombocytopenia and preparation method thereof

A technology of traditional Chinese medicine preparations and platelets, which is applied in the direction of medical formulas, medical preparations containing active ingredients, blood diseases, etc., can solve problems such as weakening the body's resistance, complications of the digestive system and cardiovascular system, and uncontrolled disease. Achieve the effects of reducing capillary permeability, promoting platelet production, and reducing platelet damage

Inactive Publication Date: 2011-01-26
李西爱
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, the treatment of this disease at home and abroad mainly adopts glucocorticoids, immunosuppression, etc., but there are many problems: 1. Long-term repeated administration is required, and the side effects are quite large, causing complications in the digestive system and cardiovascular system, and even inducing and Aggravated infection
2. Prednisone drugs clinically used to treat thrombocytopenic purpura can easily cause side effects such as Cushing's syndrome, virilization, high blood pressure, and weakened body resistance; immunosuppressant cyclophosphamide drugs can inhibit Hematopoietic function of bone marrow; Danazol drugs have side effects of damage to liver function
3. The curative effect is not good, and 25% of the patients' condition cannot be controlled
Although these varieties play a certain role in the prevention and treatment of this disease, they all have the unfavorable factor of poor pertinence.

Method used

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  • Traditional Chinese medicine preparation for treating immune thrombocytopenia and preparation method thereof
  • Traditional Chinese medicine preparation for treating immune thrombocytopenia and preparation method thereof
  • Traditional Chinese medicine preparation for treating immune thrombocytopenia and preparation method thereof

Examples

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Effect test

preparation example Construction

[0047] The preparation method of the honey refining pill of Chinese medicine preparation of the present invention is:

[0048] Crushing steps: Selaginella 500g, Acanthopanax 500g, Morinda officinalis 1000g, Dandelion 500g, Panax notoginseng 1000g, Caulis Spatholobus 500g, Radix Paeoniae Alba 500g, Angelica 500g, Atractylodes macrocephala 500g, Salvia miltiorrhiza 1000g, Rehmannia 1000g, Astragalus 1000g, Codonopsis pilosula 500g, Agrimony 500g and Cuscuta 1000g; put them into a pulverizer and crush them into fine powder, put them in an acid and alkali resistant staining pot, soak them with alcohol for 20 days at room temperature, press and filter the soaked liquid and medicinal residues, and separate Finally, take the filtrate; stir the filtrate and add 5 times the weight of the prescription drug in distilled water, decoct it twice, each time for 45 minutes, filter, combine the second filtrate, concentrate to one-tenth of the weight of the original solution, that is, every 1ml ...

specific Embodiment 1

[0100] Specific embodiment 1: Lin, female, 6 years old, the patient's parents reported that the sick child suddenly found skin and mucous membrane bleeding, and multiple bleedings such as patient's limbs, trunk and even whole body skin, oral mucosa, gingiva, and nasal mucosa. Plaques or large patches of bleeding ecchymosis appear. Sometimes the epistaxis does not stop, and there may be viral infection, respiratory tract infection, and mild splenomegaly 3 weeks before the onset. The investigation was acute immune thrombocytopenia. Selaginella 5g, Acanthopanax 5g, Morinda officinalis 10g, Dandelion 5g, Panax notoginseng 10g, Caulis Spatholobus 5g, Paeoniae Alba 5g, Angelica 5g, Atractylodes macrocephala 5g, Salvia miltiorrhiza 10g, Habitat 5g, Astragalus 10g, Codonopsis 5g, Agrimony 5g and Cuscuta 10g were made into honey-refined pills and taken for 15 days as a course of treatment. After 2 courses of treatment, the situation improved and continued to take for 4 courses of trea...

specific Embodiment 2

[0101] Specific embodiment 2: Feng Mou, 46 years old, female, the patient's own prosecution suffers from respiratory tract infection for more than a month. Ecchymosis began to appear on the body, the bleeding was mild, mucosal blood blisters and gastrointestinal and urinary tract bleeding appeared, epistaxis or menorrhagia may occur, signs except petechiae and ecchymosis, no enlargement of liver, spleen, or lymph nodes. The investigation was immune thrombocytopenia. Selaginella 10g, Acanthopanax 15g, Morinda officinalis 10g, Dandelion 15g, Panax notoginseng 10g, Caulis Spatholobus 10g, Paeoniae Alba 10g, Angelica 15g, Atractylodes macrocephala 15g, Salvia miltiorrhiza 10g, Habitat 15g, Astragalus 10g, Codonopsis 15g, Agrimony 15g and Cuscuta 10g were made into honey-refined pills and taken. 15 days was a course of treatment. After 1 course of treatment, the situation improved. After taking 5 courses of treatment, the condition was completely controlled and there was no recurre...

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Abstract

The invention provides a traditional Chinese medicine preparation for treating immune thrombocytopenia (ITP) and a preparation method thereof. The traditional Chinese medicine preparation comprises the following components in parts by weight: 1 part of selaginella tamariscina, 1-2 parts of acanthopanax, 1-2 parts of morinda officinalis, 1-2 parts of dandelion, 1-2 parts of pseudo-ginseng, 1-2 parts of spatholobus stem, 1-2 parts of white peony root, 1-2 parts of angelica, 1-2 parts of bighead atractylodes rhizome, 1-2 parts of red sage root, 1-2 parts of radix rehmanniae, 1-2 parts of radix astragali, 1-2 parts of dangshen, 1-2 parts of agrimony and 1-2 parts of dodder. From the perspective of modern pharmacological research, the medicines contained by the traditional Chinese medicine preparation of the invention have the effects of regulating immunity, reducing platelet destruction, promoting thrombopoiesis, reducing capillary permeability and the like, thereby achieving the purpose of treating ITP. The medicines are compatible, the formula is simple and complete and hits the pathogenesis, and the medicines play the effects of removing pathogenic heat from blood, removing blood stasis, arresting bleeding, and reinforcing the spleen and kidney, thereby reducing hemorrhage of patients with ITP and alleviating various clinical symptoms.

Description

technical field [0001] The invention relates to a medical preparation containing raw materials derived from plants, animals or minerals and a preparation method thereof, in particular to a traditional Chinese medicine preparation for treating immune thrombocytopenia and a preparation method thereof. Background technique [0002] Immune thrombocytopenic purpura is an immune disease in which autoantibodies bind to platelets, causing increased destruction of platelets, leading to bleeding in the skin, mucous membranes, and internal organs. Thrombocytopenic purpura is a common hemorrhagic disease, accounting for about 70% of hemorrhagic diseases, and has an increasing trend year by year. The first onset is usually under the age of 30. The bleeding is severe at the onset, causing extensive skin and mucous membrane blood spots or ecchymosis or even subcutaneous hematoma. Long-term repeated bleeding can cause anemia and symptoms such as low fever, fatigue, and dizziness. [0003] ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P7/02A61P37/02
Inventor 姜红张小红
Owner 李西爱
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