Traditional Chinese medicine composition for treating hypertension

A composition and technology for high blood pressure, applied in the directions of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of easy rebound of blood pressure, large side effects, fluctuation, etc.

Active Publication Date: 2011-05-25
谭元生 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After taking it, it has the disadvantages that blood pressure is easy to rebound, fluctuate, and has large side effects.

Method used

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  • Traditional Chinese medicine composition for treating hypertension
  • Traditional Chinese medicine composition for treating hypertension
  • Traditional Chinese medicine composition for treating hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1 Granule dosage form of pharmaceutical composition of the present invention

[0015] Using the conventional method of preparing granules, take 1.4 parts of Rhizoma Chuanxiong, 1.8 parts of Uncaria, and 1.2 parts of Ophiopogon japonicus. Doubling the amount of water and decocting for 1.5 hours, filtering, concentrating the combined filtrate to a relative density of 1.30 (measured at 60°C), drying, pulverizing, adding an appropriate amount of excipients, mixing, granulating, sieving, and drying to obtain a pharmaceutical combination in granular dosage form pharmaceutical preparations.

Embodiment 2

[0016] Embodiment 2 The tablet dosage form of pharmaceutical composition of the present invention

[0017] Using the conventional method of preparing tablets, take 1.2 parts of Rhizoma Chuanxiong, 2 parts of Uncaria, and 1.5 parts of Radix Ophiopogon japonicus, add water and decoct twice, add 10 times the amount of water for the first time and soak for 30 minutes, decoct for 2 hours, and add water for the second time Decoct 8 times the amount of water for 1.5 hours, filter, combine and concentrate the filtrate to a relative density of 1.30 (measured at 60°C), dry and pulverize, add an appropriate amount of auxiliary materials, mix well, granulate, sieve, and dry. Further tableting and drying, the pharmaceutical composition preparation in tablet dosage form is obtained. The capsule dosage form of embodiment 3 pharmaceutical compositions of the present invention

Embodiment 3

[0018] Using the conventional method of preparing capsules, take 1.0 parts of Rhizoma Chuanxiong, 1.5 parts of Uncaria, and 1.0 parts of Radix Ophiopogon japonicus, add water to decoct twice, add 9 times the amount of water for the first time and soak for 30 minutes, decoct for 2 hours, and add water for the second time. Decoct with 7 times the amount of water for 1.5 hours, filter, combine and concentrate the filtrate to a relative density of 1.30 (measured at 60°C), dry and pulverize, add an appropriate amount of auxiliary materials, mix well, granulate, sieve, dry, and pack the obtained granules Put into capsule shell, make capsule, promptly make the pharmaceutical composition preparation of capsule dosage form.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating hypertension, which takes Ligusticum wallichii, uncaria and radix ophiopogonis as raw materials. The test result shows that the Ligusticum wallichii, the uncaria and the radix ophiopogonis have excellent interaction after compatibility of medicines, and can obviously lower the systolic pressure and the diastolic pressure of model animals with spontaneous hypertension and renal hypertension, and pressure reduction effect is long-lasting. The composition has the advantages of reasonable compound prescription and appropriate compatibility proportion, has the function on calming liver wind, nourishing yin and invigorating the circulation of blood and has definite curative effect on hypertension patients with the symptom of yin deficiency and yang excess as well as blood stasis obstructing the collaterals. The composition can be prepared into medically-acceptable solid oral preparations, such as tablets, capsules (soft capsules or hard capsules), granules and the like, can be used for treating hypertension, and is safe, effective and convenient to use.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating hypertension. Specifically, it is a traditional Chinese medicine composition of Chuanxiong, Uncaria, and Radix Ophiopogon japonicus. Background technique [0002] Hypertension is one of the most common cardiovascular diseases at present, and its high disability rate and death rate have brought serious material and spiritual damage to society and family. In my country, the prevalence rate of people over 15 years old is as high as 11.2%, and that of people over 60 years old is 43.7%. characteristics of medication. [0003] At present, the six major types of drugs used in the treatment of hypertension by western medicine are still the main antihypertensive drugs in clinical application. After taking it, it has the disadvantages that the blood pressure is easy to rebound, fluctuate, and has large side effects. Although traditional Chinese medicine treatment of hypertension ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P9/12
Inventor 谭元生王宇红
Owner 谭元生
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