Composition for relieving physical fatigue and enhancing immunologic function, preparation method thereof and application thereof

A technology that relieves physical fatigue and enhances immunity. It is applied to medical preparations containing active ingredients, food preparation, drug combinations, etc., and can solve problems such as poor safety, poor pertinence, and slow onset of action.

Active Publication Date: 2011-06-22
上海东锦食品集团有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is still a lack of ideal health care products for relieving physical fatigue in the market. The main disadvantages are poor

Method used

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  • Composition for relieving physical fatigue and enhancing immunologic function, preparation method thereof and application thereof
  • Composition for relieving physical fatigue and enhancing immunologic function, preparation method thereof and application thereof
  • Composition for relieving physical fatigue and enhancing immunologic function, preparation method thereof and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0116] Compositions 1-3

[0117]

[0118] Various components were mixed according to the above formula to obtain composition 1, composition 2 and composition 3 respectively.

[0119] The preparation method of guarana extract is:

[0120] 1. Guarana seeds were reflux extracted with 6-10 times the amount of 90% ethanol for 3 times, each time for 3 hours;

[0121] 2. Filtrate, combine the filtrates, recover ethanol under reduced pressure, concentrate under reduced pressure to 60°C to obtain extract;

[0122] 3. Spray-dry the extract (the temperature of the air inlet is 150-180° C., and the temperature of the outlet air is 60-90° C.) to obtain a spray-dried fine powder.

[0123] After testing (testing method: Determination of caffeine in GB / T 5009.139-2003 beverages), based on the total weight of the obtained guarana extract, the caffeine content is 10-12%.

[0124] The preparation method of American ginseng extract is:

[0125] 1. Pre-treatment of American ginseng: ...

Embodiment 4

[0138] safety test

[0139] Experimental animals: 20 Kunming mice, half male and half male, body weight: 18-22 g, provided by Shanghai Experimental Animal Center, Chinese Academy of Sciences. Production license number: SCXK (Shanghai) 2002-0010, experimental animal breeding room temperature 20-25 ℃, relative humidity 40-70%. Experimental animal license number: SCXK (Shanghai) 2002-0006. Animal feed was provided by Suzhou Shuangshi Experimental Animal Feed Technology Service Co., Ltd., registration number: Su E Si Sheng Zi (2002) 06.

[0140] experimental method:

[0141] (1) Test sample preparation: The daily recommended dose of this product is the total weight of each component of the composition 3 formula in Examples 1-3. Weigh 20 times the weight of composition 3 and add distilled water to 20ml, mix well Homogenized as the test sample.

[0142] (2) Test method: Toxicological safety evaluation is carried out through mouse acute oral toxicity test, mouse bone marrow polyc...

Embodiment 5

[0150] Functional test for alleviating physical fatigue

[0151] Experimental animals: Kunming white mice, license number: SCXK (Shanghai) 2002-0010, weighing 18-22 grams, female, clean animals provided by the Shanghai Experimental Animal Center of the Chinese Academy of Sciences (raised in the SPF animal room of this site). Experimental animal breeding room temperature 20-25 ℃, relative humidity 40-70%, experimental animal license number: SCXK (Shanghai) 2002-0006, animal feed, provided by Suzhou Shuangshi Experimental Animal Feed Technology Service Co., Ltd., registration certificate No.: Su E Shi Sheng Zi (2002) 06.

[0152] experimental method:

[0153] (1) Dosage design: In this experiment, three dosage groups of composition 1, composition 2 and composition 3 were set up, and distilled water blank control group and 5.6% sugar control group were also set up.

[0154] (2) Sample treatment: add distilled water to the composition to make up to 20ml, mix well and use it as a...

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Abstract

The invention discloses a composition for relieving physical fatigue and enhancing an immunologic function, a preparation method thereof and application thereof. The composite comprises 10 to 100 weight parts of guarana extract, 100 to 800 weight parts of taurine, 1 to 10 weight parts of L-lysine hydrochloride, 1 to 10 weight parts of L-isoleucine, 0.1 to 5 weight parts of L-leucine, 0.2 to 5 weight parts of L-valine, 1 to 15 weight parts of L-aspartate, 0.01 to 0.3 weight part of L-tryptophan, 0.01 to 0.3 weight part of L-phenylalanine, 0.01 to 0.3 weight part of L-threonine, 0.01 to 0.3 weight part of L-methionine, 10 to 100 weight parts of L-alanine, 10 to 100 weight parts of glycine, 1 to 15 weight parts of tea polyphenol and 1 to 20 weight parts of American ginseng extract.

Description

technical field [0001] The invention relates to the field of compositions with health care functions, in particular to a composition capable of relieving physical fatigue and enhancing immune functions, its preparation method and application. Background technique [0002] Fatigue is a physiological and psychological phenomenon in which the body's work efficiency is temporarily reduced due to long-term or overly heavy and intense labor (including mental and physical strength) under certain environmental conditions. With the progress of society and the development of the competition mechanism, people will inevitably continue to accept various pressures from work, society, and family, and they are prone to mental stress, loss of appetite, slow response, memory loss, and poor concentration. Fatigue symptoms such as inability to concentrate. Fatigue has become a serious problem of global concern. According to reports, about 14% of adult men and 20% of women in the United States ...

Claims

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Application Information

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IPC IPC(8): A61K36/82A23L1/30A61P37/04A61K31/185A61K31/198A61K31/405
Inventor 蔡愈杭陈伟何会罗殷
Owner 上海东锦食品集团有限公司
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