Novel application of alchornea trewioides extract in pharmacy
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A technology of red-backed mountain hemp stalks and extracts, which is applied in the medical application field of plant extracts, and can solve problems such as renal parenchyma damage, kidney toxicity and side effects, and treating symptoms but not the root cause
Inactive Publication Date: 2011-10-05
GUANGXI INST OF BOTANY THE CHINESE ACAD OF SCI
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Problems solved by technology
Western medicine mostly uses antibiotics for treatment, many of which have toxic and side effects on the kidneys, such as gentamicin, kanamycin, flufenacin, etc. If the treatment is not done properly, it may cause serious damage to the kidney parenchyma, or even renal failure
At the same time, some of the existing drugs treat the symptoms ...
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Embodiment 1
[0021] 1) Take the original medicinal material (dry medicinal material) of the whole plant of the stalk of the red back mountain, pulverize it, and set aside;
[0022] 2) Weigh 5 kg of crushed medicinal material, add water to decoct and extract three times, the amount of water added is 8 times, 5 times, and 4 times the weight of the medicinal material respectively, and the extraction time is 2 hours, 1.5 hours, and 1.5 hours respectively. Combine the filtrates, concentrate to the extract, and freeze-dry to obtain the water extract of the red-backed mountain hemp stalk.
Embodiment 2
[0024] 1) Take the roots and leaves (dried medicinal materials) of the red-backed mountain hemp, crush them, and set aside;
[0025] 2) Weigh 5 kg of pulverized medicinal material, add 10% ethanol and extract three times, the amount of solvent is 8 times, 5 times, and 4 times of the weight of the medicinal material respectively, and the extraction time is 2 hours, 1.5 hours, and 1.5 hours respectively. Combine the filtrates, recover until there is no alcohol smell, and dry under reduced pressure to obtain the ethanol extract of the red-backed mountain hemp stalk.
Embodiment 3
[0027] 1) Take the stalks and leaves (dry medicinal materials) of the red-backed mountain hemp, crush them, and set aside;
[0028] 2) Weigh 5 kg of pulverized medicinal materials, add 60% ethanol to extract three times, the amount of solvent is 8 times, 4 times and 3 times of the weight of medicinal materials respectively, and the extraction time is 2 hours, 1.5 hours and 1.5 hours respectively. Combine the filtrates, recover until there is no alcohol smell, and dry under reduced pressure to obtain the ethanol extract of the red-backed mountain hemp stalk.
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Abstract
The invention discloses a novel application of an alchornea trewioides extract in the pharmacy field, and in particular, an application of an alchornea trewioides extract in preparing drugs for treating nonbacterial prostatitis; and an application of an alchornea trewioides extract in preparing drugs for treating nonbacterial prostatic hyperplasia; In addition, the invention also discloses a drug composition for treating nonbacterial prostatitis and prostatic hyperplasia with the alchornea trewioides extract as an active component. Through experiment, the applicant finds that the alchornea trewioides extract can significantly decrease the prostate wet weight and the prostate index of a model animal, has a good inhibition effect on prostate glandular swelling of a nonbacterial prostatitis model rat, can improve blood circulation and promote the softening of the prostate glandular texture, and can mitigate interstitial hyperemia, edema, inflammatory cell infiltration and cell degeneration of prostate cells. Compared with existing and common western medicine, the alchornea trewioides extract has comparable or even better efficacy and less toxicity, and is safer for medication.
Description
technical field [0001] The invention relates to the field of medical application of plant extracts, in particular to a new pharmaceutical application of the extract of the red-backed mountain hemp stalk. Background technique [0002] Prostatitis and benign prostatic hyperplasia are common and refractory diseases of the genitourinary system in middle-aged and elderly people, with a high incidence rate. According to clinical statistics, the number of outpatient visits accounts for about 25% of male genitourinary system disease outpatient visits. High attention is also one of the key points and difficulties in community health work. The treatment of this disease often adopts traditional Chinese medicine or Western medicine treatment at present, and the traditional Chinese medical science is mostly according to the basic treatment principle of clearing the benefit and eliminating pathogenic factors for the excess, and invigorating the kidney and strengthening the body for the d...
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