A kind of preparation method and application of duck foot veneer extract

A technology of duck foot veneer and extract, which is applied in the field of research and development of pharmaceutical products, can solve the problems that the research on the anti-inflammatory and analgesic effects of duck foot veneer extract has not been reported yet, achieve significant anti-inflammatory and analgesic activity, and the preparation method is simple and convenient. Appropriate for promoting the effect of the application

Inactive Publication Date: 2011-12-21
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the anti-inflammatory and analgesic effects of duck foot veneer extract

Method used

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  • A kind of preparation method and application of duck foot veneer extract
  • A kind of preparation method and application of duck foot veneer extract
  • A kind of preparation method and application of duck foot veneer extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1 Preparation of duck foot vetch extract

[0023] (1) Take the bark powder of Schefflera octophylla (Lour.) Harms (the particle size of the powder is not strictly limited), and extract with 10 times the volume ratio of 95% ethanol and reflux for 3 times, each for 2 hours , Stand to filter;

[0024] (2) Combine the filtrate obtained in step (1), and recover the solvent under reduced pressure to obtain the total extract;

[0025] (3) Suspend the total extract obtained in step (2) with an appropriate amount of water (the amount of water is about 3 to 5 times the mass of the total extract), and then use petroleum ether, chloroform, ethyl acetate and n-butanol to extract each 3 times, the amount of extractant is 1 to 2 times of the aqueous solution;

[0026] (4) Combine the petroleum ether layer, chloroform layer, ethyl acetate layer and n-butanol layer extracts obtained in step (3) respectively;

[0027] (5) Combine the petroleum ether layer, the chloroform layer, the ethyl...

Embodiment 2

[0028] Example 2 Preparation of duck foot vetch extract

[0029] (1) Take the bark powder of Schefflera octophylla (Lour.) Harms, and extract 2 times with 8 times the volume ratio of 85% ethanol for reflux, 2.5 hours each time, and filter by standing;

[0030] (2) Combine the filtrate obtained in step (1), and recover the solvent under reduced pressure to obtain the total extract;

[0031] (3) Suspend the total extract obtained in step (2) with water (the amount of water is about 3 to 5 times the mass of the total extract), and then use petroleum ether, chloroform, ethyl acetate and n-butanol to extract 4 times each ; (The amount of extractant is 1 to 2 times of the aqueous solution)

[0032] (4) Combine the petroleum ether layer, chloroform layer, ethyl acetate layer and n-butanol layer extracts obtained in step (3) respectively;

[0033] (5) Combine the petroleum ether layer, the chloroform layer, the ethyl acetate layer and the n-butanol layer extracts obtained in step (4) and the a...

Embodiment 3

[0034] Example 3 Preparation of Duck Feet Wood Bark Extract

[0035] (1) Take the bark powder of Schefflera octophylla (Lour.) Harms, and use 9 times the volume ratio of 75% ethanol to reflux and extract 3 times for 2 hours each time, and then stand to filter;

[0036] (2) Combine the filtrate obtained in step (1), and recover the solvent under reduced pressure to obtain the total extract;

[0037] (3) Suspend the total extract obtained in step (2) with water (the amount of water is about 3 to 5 times the mass of the total extract), and then use petroleum ether, chloroform, ethyl acetate and n-butanol to extract 4 times each ; (The amount of extractant is 1 to 2 times of the aqueous solution)

[0038] (4) Combine the petroleum ether layer, chloroform layer, ethyl acetate layer and n-butanol layer extracts obtained in step (3) respectively;

[0039] (5) Combine the petroleum ether layer, the chloroform layer, the ethyl acetate layer and the n-butanol layer extracts obtained in step (4) ...

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PUM

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Abstract

The invention discloses a method for preparing a taxillus chinensis danser extract, an extract and application. The method comprises the following steps of: taking an ethanol extract of taxillus chinensis danser powder; sequentially extracting by using petroleum ether, chloroform, ethyl acetate and n-butyl alcohol; respectively mixing various extract liquor and aqueous solution; and decompressingand recovering solvent to obtain a petroleum ether extract, a chloroform extract, an ethyl acetate extract and an n-butyl alcohol extract. The taxillus chinensis danser extract disclosed by the invention has good anti-inflammatory analgesic activity and can be applied to preparing anti-inflammatory analgesic drugs.

Description

Technical field [0001] The invention belongs to the technical field of medical product research and development, and relates to a preparation method and application of a duck foot veneer extract. Background technique [0002] Schefflera octophylla (Lour.) Harms is a plant of the genus Araliaceae, which has a bitter taste and flat nature. The root bark and bark of the plant can be used as medicine. It has the functions of dispelling wind and dampness, promoting blood circulation and relieving pain, and mainly treating rheumatic arthralgia, traumatic fractures, traumatic bleeding. It is mostly used in the treatment of rheumatic bone pain, traumatic swelling and pain, bark hemostasis, sore throat Wait. Daffodil is mainly distributed in Yunnan, Guangdong, Guangxi and other places. It is rich in resources. It is a nectar plant in the southern winter. It has high medicinal value and has great development potential. [0003] Inflammation is a defensive response of living tissues with va...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/25A61P29/00A61P19/02A61P19/08A61P11/04A61K129/00
Inventor 沈志滨陶曙红曾凡林陈艳芬尹永芹崔红花
Owner GUANGDONG PHARMA UNIV
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