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Traditional Chinese medicine composition for treating gastric cancer

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for the treatment of gastric cancer, can solve the problems of poor chemotherapy tolerance, low CR rate of gastric cancer chemotherapy, unsatisfactory curative effect, etc., and achieve the effect of inhibiting proliferation

Active Publication Date: 2012-01-04
JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, the CR rate of gastric cancer chemotherapy is low, the survival period is not significantly prolonged, and adverse reactions such as gastrointestinal reactions and bone marrow suppression are relatively large. In addition, most patients with advanced gastric cancer have fatigue, poor appetite, and decreased physical fitness, poor immune function, and tolerance to chemotherapy. poor sex
At present, the treatment methods for gastric cancer include: surgery, chemotherapy, radiotherapy, biological therapy, etc., but the curative effects are not satisfactory, and there is no effective western medicine or Chinese patent medicine at present

Method used

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  • Traditional Chinese medicine composition for treating gastric cancer
  • Traditional Chinese medicine composition for treating gastric cancer
  • Traditional Chinese medicine composition for treating gastric cancer

Examples

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Effect test

Embodiment 1

[0028] A traditional Chinese medicine composition for treating gastric cancer is prepared from the following components in parts by weight: 13 parts of Codonopsis pilosula, 20 parts of Shengbaizhu, 13 parts of Zezhu, 13 parts of Pinellia chinensis, 20 parts of vine pear root, and 20 parts of Rhodiola rosea.

[0029] The specific preparation method is: mix the Codonopsis pilosula, raw Atractylodes macrocephala, curcuma, Fapinellia, vine pear root and rhodiola rosea in the above formula, add 18 times of water and soak for 30 minutes, decoct on high heat, boil on low heat for 2 hours, cool , filter the juice, and concentrate it.

Embodiment 2

[0031] A traditional Chinese medicine composition for treating gastric cancer is prepared from the following components in parts by weight: 10 parts of Codonopsis pilosula, 15 parts of Shengbaizhu, 10 parts of Zezhu, 10 parts of Pinellia chinensis, 10 parts of vine pear root, and 10 parts of Rhodiola rosea.

[0032] The specific preparation method is as follows: mix the Codonopsis pilosula, raw Atractylodes macrocephala, curcuma, Fapinellia, vine pear root and rhodiola rosea in the amount of the above formula, add 16 times of water and soak for 1 hour, decoct on high heat, boil on low heat for 3 hours, and cool down. , filter the juice, and concentrate it.

Embodiment 3

[0034] A traditional Chinese medicine composition for treating gastric cancer is prepared from the following components in parts by weight: 20 parts of Codonopsis pilosula, 35 parts of Shengbaizhu, 20 parts of Zezhu, 15 parts of Pinellia chinensis, 30 parts of vine pear root, and 30 parts of Rhodiola rosea.

[0035] The specific preparation method is: mix the Codonopsis pilosula, raw Atractylodes macrocephala, curcuma, Fapinellia, vine pear root and rhodiola rosea in the above formula, add 20 times of water and soak for 2 hours, decoct on high heat, boil on low heat for 4 hours, cool , filter the juice, and concentrate it.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating gastric cancer. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 10-20 parts of pilose asiabell root, 15-35 parts of fresh rhizoma atractylodis macrocephalae, 10-20 parts of zedoary, 10-15 parts of rhizoma pinelliae preparata, 10-30 parts of Chinese actinidia root and 10-30 parts of rhodiola rosea. The traditional Chinese medicine composition exerts advantages of comprehensive therapy of traditional Chinese medicine, and dialectics is combined with differentiation of disease; and according to etiology, pathogenesis and pathology features of gastric cancer, experimental observation on an in-vitro experiment for inhibiting gastric cancer SGC7901 cell proliferation by medicines and an in-vivo experiment for inhibiting transplanted tumor of gastric cancer SGC7901 cells in nude mice by medicines shows that the traditional Chinese medicine composition in the invention can induce the SGC7901 cells to produce autophagy so as to inhibit the proliferation of the gastric cancer SGC7901 cells, thereby opening a road for hope for treating patients with gastric cancer.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compound prescriptions, and in particular relates to a traditional Chinese medicine composition for treating gastric cancer. Background technique [0002] Gastric cancer has a high incidence in many countries around the world, ranking fourth among the most common malignant tumors. my country is an area with a high incidence of gastric cancer, and gastric cancer is often diagnosed at an advanced stage, and chemotherapy-based comprehensive treatment plays an important role in the medical treatment of gastric cancer. However, at present, the CR rate of gastric cancer chemotherapy is low, the survival period is not significantly prolonged, and adverse reactions such as gastrointestinal reactions and bone marrow suppression are relatively large. In addition, most patients with advanced gastric cancer have fatigue, poor appetite, and decreased physical fitness, poor immune function,...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P35/00A61P1/00
Inventor 曹鹏霍介格王小宁蔡雪婷秦凤霞朱京红丁蓉
Owner JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
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