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Method for treating cervical erosion by using preparation containing triamcinolone acetonide

A cervical erosion and preparation technology, which is applied in the field of medicine, can solve the problems of inability to recover, decreased nerve sensitivity of the vaginal wall, and impact on the quality of sexual life, etc., and achieve the effect of reducing the erosion area

Inactive Publication Date: 2012-04-18
JIAXING FUTEJI BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 2. Patients with moderate cervical erosion and severe cervical erosion usually cannot achieve recovery with existing drug treatment
The disadvantage of physical therapy is that the side effects are relatively large, and it may cause the nerve sensitivity of the inner wall of the vagina to decrease, which will affect the quality of sexual life
In addition, it is easy to relapse after treatment

Method used

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  • Method for treating cervical erosion by using preparation containing triamcinolone acetonide
  • Method for treating cervical erosion by using preparation containing triamcinolone acetonide
  • Method for treating cervical erosion by using preparation containing triamcinolone acetonide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Recipe composition:

[0051]

[0052] Preparation steps:

[0053] 1) Take glyceryl stearate, stearyl alcohol, cetyl palmitate and octyl stearate and heat to melt at 80°C.

[0054] 2) Dissolving triamcinolone acetonide in glycerin, polysorbate 60 and polysorbate 80.

[0055] 3) Dissolve the high-viscosity chitosan agent in water, and adjust the pH to 4-5 with lactic acid.

[0056] 4) Dissolve metronidazole in 3).

[0057] 5) Stir 1), 2) and 4) evenly under heating at 40°C to form a cream.

Embodiment 2

[0059] Recipe composition:

[0060]

[0061]

[0062] Preparation steps:

[0063] 1) Glyceryl stearate, stearyl alcohol, cetyl palmitate and octyl stearate were heated and melted at 80°C;

[0064] 2) dissolving triamcinolone acetonide in glycerin, polysorbate 60, and polysorbate 80;

[0065] 3) dissolving the high-viscosity chitosan agent in water, and adjusting the pH to 4-5 with lactic acid;

[0066] 4) dissolving clindamycin in 3);

[0067] 5) 1), 2) and 4) are heated at 40°C and stirred evenly to the cream.

Embodiment 3

[0069] Recipe composition:

[0070]

[0071] Preparation steps:

[0072] 1) Take polyethylene glycol stearyl ether, cetyl alcohol, isopropyl myristate, vitamin E acetate and heat to melt at 80°C;

[0073] 2) dissolving triamcinolone acetonide in glycerin, polysorbate 60, and polysorbate 80;

[0074] 3) dissolving the high-viscosity chitosan agent in water, and adjusting the pH to 4-5 with lactic acid;

[0075] 4) dissolving metronidazole in 3);

[0076] 5) 1), 2) and 4) are heated at 40°C and stirred evenly to the cream.

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PUM

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Abstract

The invention provides a method of applying a topical preparation containing triamcinolone acetonide in treating or preventing cervical erosion. The preparation can comprise triamcinolone acetonide and other accessories or be a composition of triamcinolone acetonide and one antibiotic or more antibiotics. According to the treatment method provided in the invention, a variety of topical dosage forms of the preparation containing triamcinolone acetonide can be used, e.g., vaginal cream, vaginal gelata, vaginal suppository, vaginal effervescent tablets, vaginal tablets, vaginal ointment, etc. The preparation used in the method has anti-inflammatory and vasoconstrictive effects, has effective action on reducing, shallowing and eliminating an erosion area and is effective in inhibiting recurrence of triamcinolone acetonide.

Description

technical field [0001] The invention relates to a compound preparation for treating cervical erosion, which belongs to the technical field of medicine. Background technique [0002] Cervical erosion is a frequently-occurring and common disease in women. Especially married women who have given birth, almost 60-80% have different degrees of cervical erosion. Cervical erosion can cause increased leucorrhea, leucorrhea with blood or bleeding after sexual intercourse, often with back pain, menstrual disorders, infertility and so on. If severe cervical erosion is not treated, a small number of cervical precancerous lesions or cervical cancer may occur. The occurrence of cervical erosion is due to childbirth, miscarriage, puerperium infection or surgical operation or mechanical stimulation such as sexual life damage to the cervix, pathogens invade and cause infection. Repeated induced abortion can cause varying degrees of cervical damage, giving bacteria an opportunity to cause ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/58A61P29/00A61P15/00
Inventor 惠峪张恒志袁旭东
Owner JIAXING FUTEJI BIOLOGICAL TECH
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