Allopurinol sustained release pellet and preparation method thereof

A technology for sustained-release pellets and allopurinol, which can be applied to pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc., and can solve problems such as high cost and complicated preparation.
CN102440963AInactive Publication Date: 2012-05-09COSCI MED TECH CO LTD
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
COSCI MED TECH CO LTD
Publication Date
2012-05-09
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention relates to an allopurinol sustained release pellet, which does not need to adopt special equipment, and comprises allopurinol, sustained release material and hydrophobicbase with the mass ratio of 1%-50%. The hydrophobicbase can adjust the drug release, concretely, after the sustained release pellet enters the body, the sustained release pellet is limited due to the entering of water, so the drug release is slowed down, and the function of retarding the drug release is played.
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Description

technical field

[0001] The invention relates to a novel sustained-release pellet of allopurinol. Specifically, the micropills regulate drug release through the hydrophobic matrix and sustained-release materials, and the prepared micropills have good drug release uniformity, and the micropills have a round appearance and good fluidity. Background technique

[0002] Pellets refer to all kinds of pills with a diameter of less than 2.5mm, which can be made into quick-release or sustained-release pellets according to different needs. The focus of current research is on sustained-release pellets, which are made by mixing drugs and blockers or making ordinary ball cores and then wrapping controlled-release membranes. The pellets can be compressed into tablets, and the pellets can also be packed in capsules to make capsules. Sustained-release and controlled-release pellets are a new dosage form that is developing rapidly in the world. It is popular among doctors and patients for i...

Claims

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