Valerian preparation and preparation method thereof

A kind of valerian, preparation technology, applied in pharmaceutical field

Inactive Publication Date: 2012-07-04
武汉联合药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Existing medicinal valerian preparations mainly contain valerian root powder, valerian extract, valerian tincture and compound preparations, all of which are raw materials of dry valerian root, directly powdered or po

Method used

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  • Valerian preparation and preparation method thereof
  • Valerian preparation and preparation method thereof
  • Valerian preparation and preparation method thereof

Examples

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Embodiment 1

[0070] Valerian capsule preparation, it is made from the raw material of following weight portion:

[0071]

[0072] A preparation method of valerian preparation (capsule), the steps are:

[0073] A. Use fresh valerian rhizomes and roots, wash away the dust and mud, drain and chop into pieces about 1-5cm long, and then carry out direct distillation with water-proof pressurized steam. The steam pressure at the initial stage of distillation (before the volatile oil starts to flow out) is 0.08 -0.12mPa, the steam pressure in the mid-distillation period is 0.02-0.06mPa, and the steam pressure in the later stage of distillation (10-20 minutes before the end of distillation) is 0.08-0.10mPa, and the duration is 1.5-2.5 hours. The volatile oil and medicinal residues are separated.

[0074] B. The medicinal residues are pre-dried (sun-dried or oven-dried or vacuum-dried) and placed in a percolation tank for compaction, and after soaking in 70-95% (v / v) ethanol with a concentration ...

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Abstract

The invention discloses valerian preparation, which consists of valerian volatile oil, beta-cyclodextrin, valerian extract powder, starch for pharmaceutical, ethanol, magnesium stearate and talcum powder. A preparation method comprises the steps: A. adopting fresh valerian rhizomes, washing off mud and directly performing distillation through water-jacket pressurized steam after draining the valerian rhizomes to obtain the volatile oil and decoction dregs, B. drying the decoction dregs, placing the decoction dregs, using fresh medicinal materials to percolate the decoction dregs, filtering percolation liquid, recovering ethanol and then performing concentration to obtain the valerian extract powder, C. adding beta-cyclodextrin of the volatile oil into distilled water to be shaken up, then adding the valerian volatile oil to perform lapping and inclusion, using petroleum ether to wash off volatile oil which is not included and performing drying to obtain beta-cyclodextrin inclusion powder of the valerian volatile oil, and D. mixing the beta-cyclodextrin inclusion powder of the valerian volatile oil and the valerian extract powder to be filled into capsules. The valerian preparation is safe, effective, controllable and stable, has remarkable effects of resolving tetany, relieving pain and tranquilizing and soothing the nerves on digestive tract smooth muscles and can be used for treating smooth muscle spasmodic pain.

Description

technical field [0001] The present invention relates to the technical field of pharmacy, more specifically to a valerian preparation, and also to a preparation method of a valerian preparation, which is mainly used in irritable gastrointestinal syndrome, peptic ulcer, chronic gastritis, and other causes Treatment of gastrointestinal spasmodic pain and biliary colic induced by stones or inflammation. Background technique [0002] Valerian is a perennial plant of the genus Valeriana in the Patriaceae family. It is an ancient natural medicine and is widely included in the pharmacopoeias of various countries. According to relevant research at home and abroad, the main medicinal components of valerian are in its volatile oil, non-volatile esters and organic acids. The main active ingredients in the volatile oil are oxygen-containing derivatives of some terpenes, such as borneol ester, valerianone, caraway ester, borneol, caryophyllene, limonene, etc.; the main active ingredients...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P1/00A61P1/04A61P1/06A61P1/16A61P29/00A61K125/00
Inventor 薛存宽王根才
Owner 武汉联合药业有限责任公司
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