Valerian preparation and preparation method thereof

Abstract

The invention discloses valerian preparation, which consists of valerian volatile oil, beta-cyclodextrin, valerian extract powder, starch for pharmaceutical, ethanol, magnesium stearate and talcum powder. A preparation method comprises the steps: A. adopting fresh valerian rhizomes, washing off mud and directly performing distillation through water-jacket pressurized steam after draining the valerian rhizomes to obtain the volatile oil and decoction dregs, B. drying the decoction dregs, placing the decoction dregs, using fresh medicinal materials to percolate the decoction dregs, filtering percolation liquid, recovering ethanol and then performing concentration to obtain the valerian extract powder, C. adding beta-cyclodextrin of the volatile oil into distilled water to be shaken up, then adding the valerian volatile oil to perform lapping and inclusion, using petroleum ether to wash off volatile oil which is not included and performing drying to obtain beta-cyclodextrin inclusion powder of the valerian volatile oil, and D. mixing the beta-cyclodextrin inclusion powder of the valerian volatile oil and the valerian extract powder to be filled into capsules. The valerian preparation is safe, effective, controllable and stable, has remarkable effects of resolving tetany, relieving pain and tranquilizing and soothing the nerves on digestive tract smooth muscles and can be used for treating smooth muscle spasmodic pain.

Description

technical field [0001] The present invention relates to the technical field of pharmacy, more specifically to a valerian preparation, and also to a preparation method of a valerian preparation, which is mainly used in irritable gastrointestinal syndrome, peptic ulcer, chronic gastritis, and other causes Treatment of gastrointestinal spasmodic pain and biliary colic induced by stones or inflammation. Background technique [0002] Valerian is a perennial plant of the genus Valeriana in the Patriaceae family. It is an ancient natural medicine and is widely included in the pharmacopoeias of various countries. According to relevant research at home and abroad, the main medicinal components of valerian are in its volatile oil, non-volatile esters and organic acids. The main active ingredients in the volatile oil are oxygen-containing derivatives of some terpenes, such as borneol ester, valerianone, caraway ester, borneol, caryophyllene, limonene, etc.; the main active ingredients...

AI Technical Summary

Problems solved by technology

[0003] Existing medicinal valerian preparations mainly contain valerian root powder, valerian extract, valerian tincture and compound preparations, all of which are raw materials of dry valerian root, directly powdered or powdered with medium and low concentration ethanol (60% or The following) are extracted and prepared, and most of them have mild sedative effects, so they are only used for adjuvant treatment of insomnia, anxiety and epilepsy

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