Use of Lactoferrin in Prevention and Treatment of Tumor Metastasis

A technology of lactoferrin and human lactoferrin is applied in the field of preventing and inhibiting tumor metastasis, which can solve the problems of lack of methods and drugs for tumor metastasis.
CN102600459BActive Publication Date: 2015-09-23SHANGHAI TRANSGENIC RES CENT
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHANGHAI TRANSGENIC RES CENT
Publication Date
2015-09-23

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Abstract

The invention provides the usage of lactoferrin in prevention and treatment of tumor metastasis. Particularly, the invention provides the usage of the lactoferrin in preparation of a medicine for preventing or inhibiting tumor metastasis or tumor cell migration. The pharmacology experiment in the invention proves that the human lactoferrin has good prevention and treatment effects for the tumor metastasis, so that metastasis, colonization and growth of malignant tumors such as mouse melanoma and the like can be obviously inhibited.
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Description

technical field

[0001] The invention relates to the field of medicine, especially the fields of biological pharmacy and tumor treatment. More specifically, the present invention relates to a method for preventing and inhibiting tumor metastasis by administering human lactoferrin or a composition combined with other anticancer drugs. Background technique

[0002] Lactoferrin (Lactoferrin, LF) is a multifunctional basic glycoprotein with a molecular weight of about 80KD, which mainly exists in mammalian exocrine fluids (such as: milk, tears, sweat, saliva, semen, etc.) and neutrophils . LF is abundant in human milk, the content in colostrum can reach 7g / L, and the content in mature milk decreases and tends to be balanced, usually at the level of 1g / L.

[0003] Since LF was first isolated from cow's milk in 1939, its biological activities such as promoting the absorption and delivery of iron in the body, antibacterial, antiviral infection, and regulating the body's immunity h...

Claims

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