Traditional Chinese medicine preparation for treating oral inflammation and preparation method thereof

A technology of traditional Chinese medicine preparations and stomatitis, which is applied in the field of traditional Chinese medicine preparations for the treatment of stomatitis, can solve the problems of high price, large side effects, and easy recurrence of western medicines, and achieve the effects of no adverse reactions, simple medication, and rich sources

Active Publication Date: 2012-09-26
HEILONGJIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are many types of drugs for the treatment of stomatitis, mainly western medicines with anti-inflammatory effects, but most of the western medicines

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] This example is a granule with sugar, and the dosage of each raw material is: Acanthopanax 1kg, Sanyinhua 1kg, Raw Licorice 1kg, Ainaxiang 1kg, Loofah 1kg, Verbena 1kg.

[0039] Prepared as follows:

[0040] (1) Weigh the raw materials according to the above formula and put them into the extraction tank, add 12L of water, heat to 60°C for extraction for 6 hours, filter to obtain the filtrate;

[0041] (2) Concentrate the filtrate to a relative density of 1.09 (measured at 60°C), cool to room temperature, add 95% (v / v) ethanol until the ethanol concentration is 75% (v / v), stir evenly, and refrigerate After 12 hours, take the supernatant to recover ethanol until there is no alcohol smell, and concentrate to an extract with a relative density of 1.30 (measured at 60°C);

[0042] (3) Add sugar, starch slurry, binder, wetting agent and other auxiliary materials to make a soft material. The amount of auxiliary materials is 9 times the weight of the extract used, and then gra...

Embodiment 2

[0045] This example is a sugar-free granule, and the dosage of each raw material is: Acanthopanax 4kg, Sanyinhua 8kg, Raw Licorice 4kg, Ainaxiang 6kg, Loofah 4kg, Verbena 8kg.

[0046] Prepared as follows:

[0047] (1) Weigh the raw materials according to the above formula and put them into the extraction tank, add 136L of water, heat to 60°C and extract twice, each extraction for 8 hours, filter, and combine the filtrates;

[0048] (2) Concentrate the filtrate to a relative density of 1.12 (measured at 60°C), cool to room temperature, add 95% (v / v) ethanol until the ethanol concentration is 75% (v / v), stir evenly, and refrigerate After 24 hours, take the supernatant to recover ethanol until there is no alcohol smell, and concentrate to an extract with a relative density of 1.33 (measured at 60°C);

[0049] (3) Add dextrin or cyclodextrin and sweetener, and after granulation, drying, whole grains are packed into bags to form granules, each bag contains 3g of medicine (equival...

Embodiment 3

[0052] The present embodiment is tablet, and the consumption of each raw material is identical with embodiment 2.

[0053] Extract the extract according to the method of Example 2, dry, pulverize, make granules, and press into tablets, each tablet is equivalent to 2.95g of the original medicinal material, to obtain final product.

[0054] How to take: 1-2 times a day, 4 tablets each time.

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PUM

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Abstract

The invention provides a traditional Chinese medicine preparation for treating oral inflammation and a preparation method thereof. The traditional Chinese medicine preparation mainly comprises the following raw materials in parts by weight: 1-100 parts of manyprickle acanthopanax root, 1-80 parts of lonicera confuse, 1-80 parts of raw glycyrrhiza, 1-60 parts of balsamiferou blumea herb, 1-100 parts of Chinese olive, 1-60 parts of vegetable sponge of luffa and 30-100 parts of European verbena. The preparation method comprises the following steps: water is added, the raw materials are extractedand filtered and the filtrate is taken; the filtrate is concentrated and precipitated with ethanol; supernate is taken and the ethanol is recovered until the smell of ethanol disappears; the filtrateis concentrated again; and corresponding excipient is added to obtain the traditional Chinese medicine preparation in various forms. The preparation takes natural traditional Chinese medicine as the raw materials, thereby having less toxic and side effects, treating both principal and secondary aspect of disease and thoroughly curing oral inflammation such as oral ulcer, oral smell, periodontitis, gingivitis and the like. In addition, the oral inflammation is not prone to relapse.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for treating oral inflammation. Background technique [0002] Oral inflammation is a common disease, caused by infectious systemic diseases or physical factors, and forms stomatitis when it expands. The imbalance of microbial flora in the oral cavity, local trauma or drug stimulation can all cause stomatitis, mainly manifested as oral ulcers, oral odor, gingivitis, periodontitis, etc. [0003] Oral ulcers have the characteristics of periodicity, recurrence and self-limiting, and can occur in any part of the oral mucosa, and are more common on the lips, cheeks, soft palate or gums of the oral cavity, and can spread to the pharyngeal mucosa in severe cases. With the prolongation of the course of the disease, the area and number of ulcers will increase, the pain will increase, the healing period will be prolonged, and the inter...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61P1/02
Inventor 张松波
Owner HEILONGJIANG PHARMA
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