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Traditional Chinese medicinal composition for treating acute peptic ulcer bleeding and preparation method thereof

A technology of peptic ulcer and composition, applied in the field of pharmacy, can solve problems such as aggravation, reduction of patients' quality of life, adverse reactions and the like

Inactive Publication Date: 2012-10-10
胡玲玲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the advantages of Western medicine in the treatment of this disease are mainly reflected in the hemostasis and the promotion of ulcer healing. For some common clinical symptoms, such as bloating, anorexia, dry mouth and bitter mouth, the curative effect is not obvious, or has no effect, or even aggravates the symptoms. Symptoms or related adverse reactions, which reduce the quality of life of patients to a certain extent

Method used

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Examples

Experimental program
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preparation example Construction

[0060] The present invention provides the preparation method of above-mentioned Chinese medicine composition, it comprises:

[0061] The first step is to mix Baiji, Arborvitae leaves, Puhuang, Burnet, Xueyu charcoal, Digupi, Rubia, Artemisia argyi, saffron, hematoxylin, Scrophulariaceae, and sarcophagus in proportion, and use alcohol concentration Use 70% to 80% methanol as a solvent, use the percolation method to slowly percolate at a rate of 1 to 3ml per minute, collect the percolation liquid, concentrate under reduced pressure and dry to obtain a dry paste, which is crushed into powder, and the added The quality of methanol is 3 to 5 times that of the mixture in the first step;

[0062] In the second step, mix Gorgon fruit, white peony root, ginseng, sealwort, licorice, bergamot and tangerine peel in proportion, and crush them into powder;

[0063] In the third step, add distilled water 3 to 6 times the mass of the powder obtained in the second step, decoct for 2 to 4 hour...

Embodiment 1

[0071] The powder 1 that the present invention prepares of embodiment 1

[0072]47g Baiji, 41g Arborvitae leaves, 25g Puhuang, 29g Burnet, 20g Xueyu Charcoal, 15g Digupi, 25g Rubia, 18g Artemisia argyi, 25g Saffron, 20g Sappan, 35g Scrophulariaceae, Sarcophagia 15g mixed, with alcohol concentration is 80% methanol 1300g as solvent, adopt percolation method to percolate slowly with the speed of 2ml per minute, collect percolation liquid, concentrate under reduced pressure and dry, obtain dry paste, be ground into powder; Gorgon fruit 21g, white peony root 17g, ginseng 85g, sealwort 58g, licorice 25g, bergamot 39g and tangerine peel 28g are mixed in proportion, crushed into powder, add 1100g of distilled water, decoct for 3 hours, filter to obtain the first filtrate, add the filter residue 300g of distilled water, decoct for 12 hours, filter to obtain the second filtrate, combine the filtrates, concentrate to remove 3 / 4 volume of water, add ethanol with an alcohol concentration ...

Embodiment 2

[0075] The powder 2 that embodiment 2 the present invention prepares

[0076] Jiangbai 50g, Arborvitae leaves 43g, Puhuang 28g, Burnet 32g, Xueyu charcoal 22g, Digupi 18g, Rubia 28g, Artemisia argyi 15g, Saffron 22g, Sappan 21g, Scrophulariaceae 33g, Sargassum 10g is mixed, and with alcohol concentration is 80% methanol 1300g as solvent, adopt percolation method to percolate slowly with the speed of 2ml per minute, collect percolation liquid, concentrate under reduced pressure and dry, obtain dry paste, be ground into powder; Gorgon fruit 18g, white peony root 13g, ginseng 88g, sealwort 60g, licorice 27g, bergamot 35g and tangerine peel 28g are mixed in proportion, crushed into powder, add 1100g of distilled water, decoct for 3 hours, filter to obtain the first filtrate, add the filter residue 300g of distilled water, decoct for 12 hours, filter to obtain the second filtrate, combine the filtrates, concentrate to remove 3 / 4 volume of water, add ethanol with an alcohol concentr...

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PUM

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Abstract

The invention provides a traditional Chinese medicinal composition for treating acute peptic ulcer bleeding and a preparation method thereof. The traditional Chinese medicinal composition comprises rhizoma bletillae, cacumen platycladi, cattail pollen, sanguisorba officinalis, crinis carbonisatus, cortex lycii radicis, radix rubiae, folium artemisiae argyi, stigma croci, sappan wood, radix scrophulariae, glabrous sarcandra herb, semen euryales, radix paeoniae alba, ginseng, rhizoma polygonati, liquorice, fingered citron and tangerine peel. The traditional Chinese medicinal composition provided by the invention can enhance the body immunity and improve the hemostasis effect without influencing hemoperfusion of the gastrointestinal mucosa.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine composition for treating acute peptic ulcer bleeding. Background technique [0002] Acute peptic ulcer bleeding mainly refers to ulcer bleeding that occurs in the stomach and duodenum, and is the most common cause of acute upper gastrointestinal bleeding, accounting for about 40-50%. Although most of the disease is self-limiting, and about 80% of the bleeding can be stopped by itself, but it is still potentially life-threatening. The occurrence of peripheral circulatory failure and hemorrhagic anemia can lead to death, and the mortality rate is about 10%. In addition, about 5% of bleeding cases are persistent bleeding, and 20% to 25% of patients may rebleed within 48 hours of onset. These patients with persistent bleeding or rebleeding, as well as the elderly or those with serious complications The mortality rate of patients is higher. [0003] A...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P1/04A61P7/04A61K35/36
Inventor 胡玲玲
Owner 胡玲玲
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