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External use drug for treating climacteric syndrome and preparation method thereof

A technology for external use of drugs and syndromes, applied in the field of external use of drugs for the treatment of menopausal syndrome, and the field of drugs for the treatment of menopause syndrome, can solve problems such as poor adhesion, skin irritation, plaster overflow, etc., to solve adverse reactions, stimulate the increase of openings. Large, improve the effect of permeability

Active Publication Date: 2012-10-31
GUANGDONG MARUBI BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Currently used in the market such as: topical hormone patch, first, skin ulceration and allergies are not uncommon due to the plaster preparation is to take the package therapy; second, there are still many shortcomings in the current sex hormone replacement therapy, such as increasing the burden on the liver, increasing the endometrium Cancer, breast cancer, thrombotic disease, the incidence of cholelithiasis, etc., cause certain risks to women receiving treatment; three, rubber plaster has the disadvantages of poor air permeability, skin irritation, and easy allergies; four, gel The curing time of the plaster is not easy to control, the adhesion is poor, and the paste overflows, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] An external medicine for treating menopausal syndrome, consisting of the following raw materials in weight ratio: Angelica 3%, Rhizoma Chuanxiong 1%, Bergamot 3%, Chinese yam 3%, Resveratrum 1%, Chasteberry 2%, soybean 6%, Polyethylene Glycol 7%, Tween-80 3%, Potassium Hydroxide 1%, Carbopol 2020 4%, Hydroxyethyl Cellulose 2%, Ethanol 18%, Genma BP 1%, Deionized Water 45%.

Embodiment 2

[0019] An external medicine for treating menopausal syndrome, consisting of the following raw materials in weight ratio: Angelica 3%, Rhizoma Chuanxiong 1%, Bergamot 1%, Yam 6%, Resveratrum 3%, Chasteberry 5%, Soybean 4%, Polyethylene Glycol 3%, Tween-80 1%, Potassium Hydroxide 1%, Carbopol 2020 2%, Hydroxyethyl Cellulose 3%, Ethanol 10%, Genma BP 3%, Deionized Water 55%.

Embodiment 3

[0021] An external medicine for treating menopausal syndrome, which is composed of the following raw materials in weight ratio: 5% angelica, 2% chuanxiong, 2% bergamot, 4% yam, 2% resveratrol, 4% chaste berry, 5% soybean, Polyethylene glycol 5%, Tween-80 2%, potassium hydroxide 2%, Carbopol 2020 3%, hydroxyethyl cellulose 2%, ethanol 12%, Genma bp 2%, deionized water 48%.

[0022] Implement the preparation method of the externally used medicine for treating menopausal syndrome in 1 to 3, pulverize the traditional Chinese medicine into a coarse powder and put it in the extraction tank, then put the dimethyl sulfoxide solution to moisten the coarse Chinese medicine powder, add a solvent to diffuse the coarse Chinese medicine powder, capped for 48 hours and then subjected to heat reflux extraction, heating the outlet of the extraction tank for 1 minute to kill the bacteria (because the boiling point of dimethyl sulfoxide is 189°C) to instantly kill all kinds of microorganisms and ...

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Abstract

The invention provides an external use drug for treating climacteric syndrome and further discloses a preparation method of the external use drug. The external use drug for treating the climacteric syndrome is good in therapeutic effect and convenient to take. The technical point is that the external use drug for the treating climacteric syndrome is composed, by weight, of 3%-6% of angelica sinensis, 1%-3% of ligusticum, 1%-3% of ligusticum wallichii, 3%-6% of Chinese yam, 1%-3% of veratrum album, 2%-5% of chasteberry, 3%-6% of soybean, 3%-7% of polyethylene glycol, 1%-3% of twain-80, 1%-3% of potassium hydroxide, 2%-4% of carbomer 2020,1%-3% of hydroxyethylcellulose, 10%-18% of ethanol,1%-3% of jiema bp and 30%-45% of deionized water. The external use drug belongs to the technical field of traditional Chinese medicine preparation.

Description

technical field [0001] The invention discloses a medicine for treating climacteric syndrome, specifically, an externally used medicine for treating climacteric syndrome, and belongs to the technical field of traditional Chinese medicine preparation. Background technique [0002] Menopausal syndrome is a series of symptoms caused by a drop in estrogen levels. A small number of women have obvious symptoms because the body cannot adapt quickly, but generally do not need special treatment. Very few symptoms are severe, and even affect life and work, you need to use Chinese medicine Yishen Gengniankang for treatment. It is generally believed that after women enter menopause, changes in their family and social environment can increase their physical and mental burdens, making menopausal syndrome prone to occur or aggravating certain existing symptoms. Some women with unstable mental state themselves have more obvious menopausal syndrome, even moody. Although menopausal syndrome...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P15/12
Inventor 方永生刘红聂艳峰
Owner GUANGDONG MARUBI BIOLOGICAL TECH CO LTD
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