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Stable formulations of insulinoptropic peptides

A stable and compound technology, applied in the direction of hormone peptides, glucagon, medical preparations of non-active ingredients, etc.

Inactive Publication Date: 2012-11-14
NOVO NORDISK AS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

GLP-2 may be effective in the treatment of gastrointestinal diseases

Method used

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  • Stable formulations of insulinoptropic peptides
  • Stable formulations of insulinoptropic peptides
  • Stable formulations of insulinoptropic peptides

Examples

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[0165] Example 2

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[0167] Example 3

Embodiment 3

[0169] Example 4

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Abstract

The invention provides a stable formulations of insulinoptropic peptides, comprising a stable drug composite for insulinoptropic peptides.

Description

[0001] This divisional application is based on the divisional application of the Chinese patent application with the application number 200580038571.3 and the application date as November 14, 2005, and the invention name is a stable preparation of insulin-stimulating peptide. technical field [0002] The invention relates to the field of pharmaceutical preparations. More specifically, the present invention relates to shelf-stable pharmaceutical formulations comprising insulinotropic peptides. Background technique [0003] Therapeutic peptides are widely used in medical practice. Pharmaceutical compositions of such therapeutic peptides are required to have a shelf life of several years for common use. However, peptide compositions are inherently unstable due to susceptibility to chemical and physical degradation. Chemical degradation involves changes in covalent bonds such as oxidation, hydrolysis, racemization or cross-linking. Physical degradation involves conformational...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/26A61K9/19A61K47/34A61K47/26A61K47/10A61P3/10A61P3/04A61P3/06
CPCA61K9/08A61K9/19A61K38/26A61K9/0019A61K47/10A61K47/26A61P3/10A61P3/04A61P3/06A61P43/00A61K38/22A61K47/18C07K14/605
Inventor S·路德维希森M·施莱因T·E·G·博芬C·邦德A-M·利莱奥雷D·K·恩格伦德B·R·尼尔森
Owner NOVO NORDISK AS
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