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Compound injection for treating pullorum disease, and preparation method thereof

A technology of injection and pullorum, applied in the field of veterinary medicine, can solve the problems of restrictions on the promotion of antibiotics and drug residues, and achieve the effects of reducing the amount of drugs, enhancing anti-oxidation, and improving drug efficacy

Active Publication Date: 2014-09-17
ZHENGZHOU HOUYI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the wide application of antibiotics has made the problem of drug residues in poultry products increasingly serious. In addition, the emergence of drug resistance in pathogenic bacteria has also greatly restricted the promotion of antibiotics.

Method used

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  • Compound injection for treating pullorum disease, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] This embodiment takes the preparation of 100mL compound injection for the treatment of pullorum as an example, and the preparation steps are as follows:

[0026] (1) Take the raw materials of purslane, chrysanthemum oleracea, and Pulsatilla pulsatillae, and extract them with ethanol by alcohol precipitation method. Specifically, soak each flavor of medicinal ethanol, filter and remove impurities, and use vacuum concentration and freeze-drying to obtain horseshoe crab. Extracts of Purslane, Pulsatilla and Pulsatilla;

[0027] (2) Weigh 5g of purslane extract, 3g of chicken dung extract, 1g of pulsatilla extract, 5g of propylene glycol, and 0.05g of Tween-80, mix and stir the propylene glycol and Tween-80 evenly, and then respectively Dissolve the extract of amaranth, the extract of Pulsatilla chinensis and the extract of Pulsatilla pulsatillae, stir for 2 to 3 hours, and obtain liquid a after fully dissolving;

[0028] (3) Weigh 0.1 g of sodium bisulfite, dissolve it in...

Embodiment 2

[0033] This embodiment takes the preparation of 100mL compound injection for the treatment of pullorum as an example, and the preparation steps are as follows:

[0034] (1) Take the raw materials of purslane, chrysanthemum oleracea, and Pulsatilla pulsatillae, and extract them with ethanol by alcohol precipitation method. Specifically, soak each flavor of medicinal ethanol, filter and remove impurities, and use vacuum concentration and freeze-drying to obtain horseshoe crab. Extracts of Purslane, Pulsatilla and Pulsatilla;

[0035] (2) Weigh 10g of purslane extract, 4g of chicken dung extract, 3g of pulsatilla extract, 7g of propylene glycol, and 0.08g of Tween-80, mix and stir the propylene glycol and Tween-80 evenly, and then respectively Dissolve the extract of amaranth, the extract of Pulsatilla chinensis and the extract of Pulsatilla pulsatillae, stir for 2 to 3 hours, and obtain liquid a after fully dissolving;

[0036] (3) Weigh 0.25 g of sodium bisulfite, dissolve it ...

Embodiment 3

[0041] This embodiment takes the preparation of 100mL compound injection for the treatment of pullorum as an example, and the preparation steps are as follows:

[0042] (1) Take the raw materials of purslane, chrysanthemum oleracea, and Pulsatilla pulsatillae, and extract them with ethanol by alcohol precipitation method. Specifically, soak each flavor of medicinal ethanol, filter and remove impurities, and use vacuum concentration and freeze-drying to obtain horseshoe crab. Extracts of Purslane, Pulsatilla and Pulsatilla;

[0043] (2) Weigh 15g of purslane extract, 5g of chicken dung extract, 5g of pulsatilla extract, 10g of propylene glycol, and 0.1g of Tween-80, mix and stir the propylene glycol and Tween-80 evenly, and then respectively Dissolve the extract of amaranth, the extract of Pulsatilla chinensis and the extract of Pulsatilla pulsatillae, stir for 2 to 3 hours, and obtain liquid a after fully dissolving;

[0044] (3) Weigh 0.4 g of sodium bisulfite, dissolve it i...

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Abstract

The present invention discloses a compound injection for treating pullorum disease, and a preparation method thereof, and belongs to the technical field of veterinary drugs. Per 100 ml of the injection of the present invention mainly comprises the following components, by weight, 5-15 g of a purslane extract, 3-5 g of a Chinese fevervine herb extract, 1-5 g of a Chinese pulsatilla extract, 5-10 g of propylene glycol, 0.05-0.1 g of tween-80, 0.1-0.4 g of an antioxidant, 2-8 g of taurine, and the balance of water for injection. According to the present invention, the three traditional Chinese drugs of the purslane extract, the Chinese fevervine herb extract, and the Chinese pulsatilla extract are combined so as to provide functions of heat clearing, detoxication, bacterial resistance and inflammation resistance; the taurine is adopted to match with various traditional Chinese drugs so as to significantly improve efficacy, such that the drug use amount is reduced, and production cost is reduced. In addition, the compound injection of the present invention has the following characteristics that: toxic and side-effects are low, generations of drug residue and drug resistance are avoided, and a good therapeutic efficacy for Salmonella pullorum infection is provided.

Description

technical field [0001] The invention relates to a veterinary compound injection, in particular to a compound injection for treating pullorum and a preparation method thereof, belonging to the technical field of veterinary medicine. Background technique [0002] Pullorum pullorum is a common and frequently-occurring acute infectious disease caused by Salmonella pullorum pullorum. Sick chickens often manifest as listlessness, drowsiness and fear of cold, clustering, drooping wings, half-closed eyes, shrinking head, not eating, etc. Severe manifestations are diarrhea, white, mushy and thin feces, and even pulling water, around the anus The fluff adhered to the white, lime-like "pasted buttocks", and died of sepsis. [0003] Due to the high morbidity and mortality of chicks within ten days of age, it was once thought that only chicks would be infected with the disease. Since the late 1980s, people have gradually produced new understandings through the exploration of the pathog...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61K9/08A61P31/04A61K31/185
Inventor 吴红云李建正范超杰
Owner ZHENGZHOU HOUYI PHARMA
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