Infectious chicken bronchitis vaccine

A bronchitis and chicken infectious technology, applied in the field of chicken infectious bronchitis live vaccine, can solve the problems that the glandular stomach type IB cannot be effectively controlled and has not been commercialized, and achieve the effect of reducing side effects

Active Publication Date: 2014-04-02
YEBIO BIOENG OF QINGDAO
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many researches on vaccines used to prevent glandular gastric type infectious bronchitis at home and abroad, but none of them have been commercialized yet.
At the same time, due to the large number of IBV serotypes, there has been no attenuated strain with good cross-protection on the market, and the gastric type IB cannot be effectively controlled

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Infectious chicken bronchitis vaccine
  • Infectious chicken bronchitis vaccine
  • Infectious chicken bronchitis vaccine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0010] The present invention will be further described below in conjunction with specific embodiments. Those skilled in the art should understand that the details and forms of the technical solutions of the present invention can be modified or replaced without departing from the spirit and scope of the present invention, but these modifications and replacements all fall within the protection scope of the present invention.

[0011] One, the screening of the chicken infectious bronchitis attenuated YB160 strain used in the present invention

[0012] Use 10-11 day-old SPF chicken embryos to carry out continuous passage to attenuate the virulence of infectious bronchitis. In each generation, 4 SPF chicken embryos were inoculated through the allantoic cavity, and the attenuation evaluation was carried out for 160 generations. Get 10, 20, 30, 40, 50, 60, 70, 80, 90, 100, 110, 120, 130, 140, 150, 160 inoculated virus strains to infect 1-day-old SPF chickens. Results There were no d...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a live vaccine for infectious chicken bronchitis. The live vaccine consists of an antigen and a vaccine adjuvant, wherein the antigen comprises infectious chicken bronchitis viral strain with a collection code CGMCC No. 6752. The prepared vaccine can be used to prevent glandular stomach-type infectious chicken bronchitis. Furthermore, the infectious chicken bronchitis virus constituting the vaccine is a low virulent strain obtained by passage several times, thus reducing the side effect caused by the existing infectious bronchitis virus as the antigen.

Description

technical field [0001] The invention belongs to the technical field of poultry vaccines, in particular to a live chicken infectious bronchitis vaccine. Background technique [0002] Infectious bronchitis (IB) is an acute and highly contagious respiratory disease caused by infectious bronchitis virus (IBV), characterized by tracheal rales, coughing, and sneezing; It is characterized by a reduction in egg quality and decreased egg quality; sick chickens often die due to respiratory, kidney or digestive tract infections. The disease was first reported in the United States by Schalk et al. in 1931, and in 1936 Beach and Hudson determined that the pathogen of the disease was a virus. So far, the disease has been widely prevalent in the world and has brought serious harm to the chicken industry. In my country, Kuang Ronglu (1972) first discovered the disease in Guangdong; by the late 1970s, Zheng Furong et al. in Hangzhou, Wu Zhida et al. in Shanghai, Ai Guoguang et al. in Beiji...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K39/215A61P31/14
Inventor 宋新宇范根成杜元钊王红李晓林郭伟伟马爽
Owner YEBIO BIOENG OF QINGDAO
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap