Traditional Chinese medicine composition for curing herpes simplex viral keratitis and preparing method thereof

A technology for viral keratitis and herpes simplex, which is applied in the field of traditional Chinese medicine, can solve the problems of drug resistance, poor clinical application effect, unsatisfactory curative effect of herpes simplex virus keratitis, etc., to speed up vision recovery, Shorten the course of treatment and improve the effect of curative effect

Inactive Publication Date: 2013-04-17
CHONGQING XUANNU BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The treatment of Western medicine for herpes simplex virus keratitis is mainly based on chemically synthesized nucleoside antiviral drugs, but these drugs are prone to drug resistance, and the clinical application effect is not good, especially for recurrent herpes simplex virus keratitis. Keratitis curative effect is better than ideal

Method used

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  • Traditional Chinese medicine composition for curing herpes simplex viral keratitis and preparing method thereof
  • Traditional Chinese medicine composition for curing herpes simplex viral keratitis and preparing method thereof
  • Traditional Chinese medicine composition for curing herpes simplex viral keratitis and preparing method thereof

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preparation example Construction

[0083] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition, when the dosage form of the Chinese medicine composition is eye drops, it is specifically:

[0084] The first step is to mix the components in proportion, put them into a pulverizer and pulverize them into fine powders. After the fine powders are sieved, put them into an acid and alkali resistant dipping pot. After 20 days, press and filter the impregnated liquid and medicinal residues, and take the filtrate after separation to obtain the first filtrate;

[0085] In the second step, the filter residue is added with 60% to 80% ethanol with an alcohol concentration of 3 to 5 times its mass, heated and refluxed for 2 to 4 hours, filtered, and the filter residue is added with an alcohol concentration of 3 to 5 times its mass. 60% to 80% ethanol, heat and reflux for extraction for 2 to 4 hours, filter, and combine the filtrates to obtain the second filtrate;

[0086...

Embodiment 1

[0100] The concrete preparation of embodiment 1 eye drops 1

[0101] Mix 30g Mimenghua, 45g Gujingcao, 35g Shayuanzi, 25g Chushizi, 20g calamina, 80g Qinpi, 25g mulberry leaves, 50g goose grass, 30g Senecio, 25g Ligustrum lucidum, 60g Radix Isatidis, 40g ginseng leaves, 35g astragalus, 25g white peony, 30g bupleurum, 65g coptis, 30g mulberry, 20g Abutilon, 30g motherwort, 35g salvia miltiorrhiza, 30g poria cocos, 15g green leaf gallbladder, 25g plantain, 50g dogwood, and cassia Mix 35g, put it into a pulverizer and crush it into fine powder. After the fine powder is sieved, put it into an acid and alkali resistant dipping pot. Squeeze and filter, take the filtrate after separation to obtain the first filtrate, add 3 kg of ethanol with an alcohol concentration of 80% to the filter residue, heat and reflux for extraction for 4 hours, filter, add 2 kg of ethanol with an alcohol concentration of 80% to the filter residue, and heat and reflux for extraction 4h, filter, combine the...

Embodiment 2

[0102] The specific preparation of embodiment 2 eye drops 2

[0103] Mix 25g Mimenghua, 40g Gujingcao, 30g Shayuanzi, 20g Chushizi, 15g calamine, 75g Qinpi, 20g mulberry leaves, 45g goose grazing grass, 25g Senecio, 20g Ligustrum lucidum, 55g Radix Isatidis, 35g ginseng leaves, 30g astragalus, 20g white peony, 25g bupleurum, 60g coptis, 25g mulberry, 15g Abutilon seed, 25g motherwort, 30g salvia miltiorrhiza, 25g poria cocos, 10g green leaf gallbladder, 20g plantain, 45g dogwood, and cassia Mix 30g, put it into a pulverizer and crush it into fine powder. After the fine powder is sieved, put it into an acid and alkali resistant dipping pot. Squeeze and filter, take the filtrate after separation to obtain the first filtrate, add 2 kg of ethanol with an alcohol concentration of 80% to the filter residue, heat and reflux for extraction for 4 hours, filter, add 1 kg of ethanol with an alcohol concentration of 80% to the filter residue, and heat and reflux for extraction 4h, filter...

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Abstract

The invention provides a traditional Chinese medicine composition for curing herpes simplex viral keratitis. Bulk drugs of the traditional Chinese medicine composition include butterflybush flowers, eriocaulon buergerianum, flatstem milkvetch seeds, fructus broussonetiae, calamine, barks of ash, folium mori, centipeda minima, groundsel, fruit of glossy privet, isatis roots, ginseng leaves, astragalus mongholicus, radix paeoniae alba, radix bupleuri, coptis chinensis, mulberries, piemarker, leonurus, roots of red-rooted salvia, poria cocos, mile swertia, plantain herb and concha haliotidis. The traditional Chinese medicine composition for curing herpes simplex viral keratitis can be used for adjusting the immune system, improves the immunologic function, is anti-inflammatory and antiviral, effectively avoids recurrence, and has the advantages of improving the curative effect, shortening the treatment course, reducing the recurrence rate and complication and quickening the vision recovery compared with simple western medicine treatment.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating herpes simplex virus keratitis and a preparation method thereof. Background technique [0002] Herpes simplex virus keratitis (HSK) is mainly caused by herpes simplex virus type I (HSV-1) infection of the eye. It is one of the most serious infectious eye diseases in the world today, and its incidence and blindness account for Corneal disease ranks first, accounting for 63.2% of corneal blindness. It is estimated that there are 50,000 new or recurrent herpes simplex virus keratitis patients in the United States every year, and there may be more than 10 million patients in the world. [0003] Herpes simplex virus host infection is generally divided into acute phase, latent phase, and recurrent phase. When the immunity is low, the latent virus is easily activated and relapses, resulting in protracted cours...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K9/08A61K9/06A61K9/00A61P27/02A61P31/22
Inventor 不公告发明人
Owner CHONGQING XUANNU BIOTECH
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