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Traditional Chinese medicine suppository for curing colpitis and preparation method thereof

A vaginitis and suppository technology, applied in the field of medical preparations, can solve the problems of inability to comprehensively treat vaginitis, unsatisfactory clinical effects, incomplete treatment, etc., achieve good social value and economic benefits, convenient administration, and anti-inflammatory Strong insect repelling effect

Active Publication Date: 2013-04-17
广州震亨药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are many medicines for the treatment of gynecological inflammation, and the routes of administration include external application and oral administration. The dosage forms of medicines include lotions, suppositories, gels, tablets, capsules, powders, etc., such as metronidazole for the treatment of trichomonas vaginitis There are clindamycin suppositories or tablets for the treatment of fungal vaginitis, clindamycin for the treatment of non-specific vaginitis, etc., and some Chinese patent medicines. , the curative effect is not significant, the treatment is not thorough, or the side effects are relatively large, resulting in repeated attacks or long-term cure and other shortcomings, and there are certain limitations in the treatment of vaginitis diseases, it is impossible to treat vaginitis comprehensively, and the clinical effects are not satisfactory.

Method used

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  • Traditional Chinese medicine suppository for curing colpitis and preparation method thereof
  • Traditional Chinese medicine suppository for curing colpitis and preparation method thereof
  • Traditional Chinese medicine suppository for curing colpitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044]Embodiment 1: the making process of suppository of the present invention is: with Radix 1000g, Cortex Phellodendri 1000g, Sophora flavescens 1000g, Kochia scoparia 1000g, white moss bark 1000g, Angelica 1000g, Toosendan 1000g, Ume 1000g, Smilax smilax 1000g, Lingxiaohua 1000g, 1000g mint, 1000g comfrey, 1000g baiji, 1000g motherwort, 1000g raspberry, 1000g milletanus, 1000g eclipta, 1000g patinella, 1000g skullcap. Firstly, the crude drug is pulverized into a coarse powder, further pulverized, passed through a 100-mesh sieve, so that the amount of fine powder passing through the 100-mesh sieve reaches 30%, and the fine powder a is collected through the 100-mesh sieve to obtain fine powder a; Coarse powder that cannot pass through a 100-mesh sieve is put into a multi-functional extraction tank for extraction twice. For the first time, add 8-10 times the amount of ethanol to decoct for 1-2 hours, and for the second time add 4-8 times the amount of water to decoct for 1-2 ho...

Embodiment 2

[0045] Embodiment 2: the production process of the suppository of the present invention can also be: with 1500g of Radix Phellodendri, 1500g of Cortex Phellodendri, 1500g of Sophora Sophora, 1500g of Kochia Cortex, 1500g of Cortex Alba, 1500g of Angelica Sinensis, 1500g of Toosendan, 1500g of Ume, 1500g of Smilax Smilax , Ling Xiaohua 1000g, Comfrey 1000g, Leonurus 1000g, Raspberry 1000g, Millipeda 1000g, Eclipta 1000g, Patrinia 1000g, Scutellaria baicalensis 1000g. Blend, chop, soak. The soaked crude drug is heated and refluxed twice for 1 to 2 hours each time, and the two extracts are combined and left to stand. Then add 5-8 times the amount of 60-70% ethanol to the above-mentioned medicinal dregs extracted by water, heat and reflux to extract twice, each time for 1-2 hours, and combine the two extracts to stand still. Combine the above two extracts, concentrate the filtrate with a relative density of 1.35 (80°C) under reduced pressure, recover ethanol, adjust the specific ...

Embodiment 3

[0046] Embodiment 3: the preparation method of the suppository of the present invention can also be: with 1000g of Radix Phellodendri, 1000g of Cortex Phellodendri, 1000g of Sophora Sophora, 1000g of Kochia Cortex, 1000g of Cortex Alba, 1000g of Angelica, 1000g of Toosendan, 1000g of Ume, 1000g of Smilax Smilax , 1500g Lingxiaohua, 1500g mint, 1500g comfrey, 1500g white and 1500g motherwort, 1500g raspberry, 1500g Caulis Spatholobus, 1500g Eclipta, 1500g Patrinia chinensis, 1500g Scutellaria baicalensis, add 5-10 times the amount of water for soaking Extract twice for 1-2 hours; extract by heating for 1-2 hours, concentrate to extract, and become component 1; soak the remaining dregs in 60-90% ethanol for 0.5-1.5 hours, extract twice, each time 1- After 2 hours, the extracts were combined, filtered, concentrated, 80-160 mesh filtered, and the supernatant after centrifugation at 6000-10000 rpm was ultrafiltered through an ultrafiltration column with a cut-off molecular weight of...

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PUM

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Abstract

The invention provides a traditional Chinese medicine suppository for curing colpitis, and bulk drugs in the suppository in part by weight are as follows: 10-20 parts of radix stemonae, 10-20 parts of golden cypress, 10-20 parts of radix sophorae flavescentis, 10-20 parts of fructus kochiae, 10-20 parts of dittany bark, 10-20 parts of angelica sinensis, 10-20 parts of szechwan Chinaberry fruit, 10-20 parts of smoked plum, 10-20 parts of rhizoma smilacis glabrae, 10-20 parts of Chinese trumpet creeper, 10-20 parts of mentha haplocalyx, 10-20 parts of lithospermum, 10-20 parts of rhizoma bletillae, 10-20 parts of motherwort, 10-20 parts of raspberry, 10-20 parts of caulis spatholobi, 10-20 parts of eclipta alba and 10-20 parts of patrinia scabiosaefolia fisch. The suppository adopts the integral technology of stype and tampon, and compensates deficiency of the common suppository that the common suppository cannot be delivered to the deep of vagina; the invention solves the difficult problem, the prepared suppository brings the drug therapeutic effect into full play, has the advantages of excellent safety and feasibility, reaches the focus of infection to ward off disease, and has the advantages of quickly relieving itching, completely sterilizing, being strong in antiphlogosis and deinsectization, convenient for administration and low in cost and the realization of easily-manufactured drug compared with the prior art.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine suppository for treating vaginitis and a preparation method thereof. Background technique [0002] Vaginitis is a kind of gynecological common disease, frequently-occurring disease, often perplexes many women, and severe case can influence patient's study, work and the whole life of women. The main clinical manifestations are fungal vaginitis, trichomonal vaginitis, and bacterial vaginosis. This disease belongs to the category of leukorrhagia and pruritus vulvae in traditional Chinese medicine. The main clinical manifestations are excessive leukorrhea, abnormal changes in color and quality. Vulva and vagina itching unbearable, even unbearable itching pain, restlessness. There are many causes of this disease, and the manifestations are different, but in general the pathogenesis is mostly releva...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/02A61P15/02
Inventor 不公告发明人
Owner 广州震亨药业有限公司
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