Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine composition and preparation method thereof

A technology of composition and natural medicine, applied in the direction of drug combination, pharmaceutical formulation, anti-tumor drug, etc., can solve the problems of dehydration, malnutrition, acid-base balance disorder of patients, etc., and achieve increased inhibitory effect, obvious synergy, and enhanced inhibition effect of action

Inactive Publication Date: 2013-07-03
张宗升
View PDF4 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which will bring great disadvantages to the recovery of the body and bring certain difficulties to periodic chemotherapy. Therefore, it is effective for chemotherapy-related diarrhea. Treatment has become an important part of the overall care of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition and preparation method thereof
  • Traditional Chinese medicine composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0030] The first step: preparation of various extracts

[0031] (1) Preparation of Concentrated Extract of Hawthorn Artemisia Artemisiae Leaf Decoction

[0032] According to the compatibility ratio of 1:1 or other ratios of 1-5:1, take hawthorn and mugwort leaves, add 10 times the amount of distilled water, soak for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, and save the filtrate. Add 6 times distilled water to the slag, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure in a vacuum oven at 70°C for 36 hours to obtain a yellow powder.

[0033] (2) Preparation of Hawthorn Total Flavonoids

[0034] Take the hawthorn pulp, extract twice with 60% ethanol under reflux, each time for 1.5h, combine the extracts, recover the ethanol to obtain the extract, add appropriate amount of distilled water to the e...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a natural medicine composition, a preparation method thereof, and an application of the composition in preparation of a toxicity reducing and efficacy enhancing medicine for cancer chemotherapy. The natural medicine composition is composed of a hawthorn and folium artemisiae argyi extract after water decoction and concentration, hawthorn total flavonoids, and a folium artemisiae argyi ethyl acetate extract in a ratio of (1-5): (3-9): (2-6). The composition has an excellent curative effect on diarrhea related with the cancer chemotherapy, and can enhance the effect on the cancer chemotherapy simultaneously.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of the concentrated extract of Hawthorn Artemisia argyi leaves decocted in water, total flavonoids of hawthorn and Artemisia argyi leaf ethyl acetate extract, and the preparation method of the natural medicine composition And the use of the natural medicine composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/734A61P35/00A61P1/12
Inventor 张宗升
Owner 张宗升
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com