PET calibrations with varying coincidence windows

A technology for calibrating phantoms and time windows, which is applied in radiation measurement, instruments for radiological diagnosis, diagnosis, etc., can solve the problems of time consumption and achieve the effect of reducing calibration time

Active Publication Date: 2013-07-24
KONINKLIJKE PHILIPS ELECTRONICS NV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Each calibration procedure is very time consuming, typica

Method used

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  • PET calibrations with varying coincidence windows
  • PET calibrations with varying coincidence windows
  • PET calibrations with varying coincidence windows

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[0019] The subject innovation overcomes the time-consuming and labor-intensive problem of scanner calibration by interleaving the setting of concurrent time windows in SUV calibration to reduce the calibration duration. In another embodiment, the calibration duration is reduced by taking SUV and normalized calibration acquisitions at the largest concurrency window and post-processing the data for the desired concurrency window.

[0020] figure 1 A standard uptake value (SUV) acquisition sequence 10 is shown that uses a staggered concurrent window setup for single SUV calibration and normalization across multiple concurrent windows, thereby eliminating the need for separate SUV and Normalization calibration required. exist figure 1 In , three staggered time windows (eg, 2ns, 4ns, and 6ns) are shown for 20 frames (labeled 0-19). Each frame is divided into three parts, each part corresponding to one of the time windows. In this way, random events in the PET scanner are reduce...

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Abstract

When calibrating a positron emission tomography (PET) scanner, a radioactive calibration phantom is scanned over a period of several half lives to acquire a plurality of frames of scan data. Interlaced timing windows are employed to facilitate acquiring coincidence data for a plurality of coincidence timing windows and energy windows during a single calibration scan. Coincident events are binned according to each of a plurality of selected coincidence windows, and the PET scanner is calibrated for each of the plurality of coincidence timing windows using data acquired from the single calibration scan.

Description

technical field [0001] This application is particularly applicable to positron emission tomography (PET) systems, and in particular relates to PET scanner calibration. However, it will be appreciated that the described techniques may also find application in other medical imaging device calibration systems, other calibration scenarios, or other scanner calibration techniques. Background technique [0002] As described in US Patent No. 7718954, a typical PET scanner performs a normalization calibration to correct for non-uniform 3D detector response, which typically takes about 6 hours. In addition, this scanner is calibrated with Standard Uptake Values ​​(SUV), which provides the conversion of counts in images to radioactive concentrations. The calibration used a decaying F-18 source and could have taken 11 hours or more to complete. [0003] Any event measured by the PET scanner and occurring within a concurrent time window (e.g., 6ns), even two random single events, was ...

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Application Information

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IPC IPC(8): G01T1/29G01T7/00
CPCG01T1/2985A61B6/583G01T1/164G01T1/1648A61B6/037G01T7/00G01T1/2964
Inventor T·L·劳伦斯J·A·科尔特姆尔
Owner KONINKLIJKE PHILIPS ELECTRONICS NV
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