The invention belongs to the field of
magnetic particle imaging, particularly relates to a
system function calibration method and device for
magnetic particle imaging without
magnetic field lines, and aims to solve the problem of poor
system function effect during magnetic particle image reconstruction in the prior art. The method comprises the following steps: acquiring an empty background
signal, and fixing a
calibration phantom at a central position without a
magnetic field line; according to the normal direction of the non-magnetic-
field line, moving the non-magnetic-
field line or calibrating the phantom and synchronously acquiring an original
signal; according to the empty background
signal and the original signal, determining an effective signal and extracting a
target signal; constructing a mapping array according to the relative distance between the non-
magnetic field line and the
calibration phantom, performing up-sampling, and mapping to a calibration space of a
system function; and calculating the relative distance of each point in the system function and
pairing and filling the calibration data to obtain a calibrated system function. According to the method, the measurement and calibration of the system function can be completed only by gradually scanning the non-magnetic
field line along the normal single direction, the interference is small, and the efficiency and the accuracy are higher.