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Traditional Chinese medicine composition for treating primary dysmenorrheal and preparation method thereof

A primary dysmenorrhea and composition technology, applied in the direction of drug combination, pharmaceutical formula, non-central analgesics, etc., can solve the problems of difficult to obtain lasting, satisfactory curative effect, multiple side effects, etc.

Active Publication Date: 2013-08-21
HEBEI AOXING GROUP PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no specific therapy, and symptomatic treatment is generally adopted, as well as non-steroidal anti-inflammatory drugs, hormones, contraceptives, and prostaglandin antagonists. Some effects have been achieved, but it is still difficult to obtain lasting and satisfactory curative effects, and there are many side effects

Method used

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  • Traditional Chinese medicine composition for treating primary dysmenorrheal and preparation method thereof
  • Traditional Chinese medicine composition for treating primary dysmenorrheal and preparation method thereof
  • Traditional Chinese medicine composition for treating primary dysmenorrheal and preparation method thereof

Examples

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Effect test

Embodiment 1

[0099] A traditional Chinese medicine capsule for treating primary dysmenorrhea (syndrome of stagnation of qi stagnation and blood stasis due to cold condensate). 100 parts of medicine, 100 parts of Evodia rutaecarpa, 150 parts of Puhuang.

[0100] The preparation method of present embodiment product is:

[0101] (1) Weigh Corydalis Corydalis, Angelica, Chuanxiong, Wuyao, Evodia decoction pieces, and Puhuang according to the ratio of parts by weight, wherein Corydalis Corydalis, Angelica, Chuanxiong, and Aconitum are pulverized into coarse powder;

[0102] (2) Add 10 times the weight of water of angelica, chuanxiong, wuyao, and evodia to boil, keep boiling, and extract for 5 hours to obtain water extract, volatile oil and medicinal residue, among which the water extract is directly filtered to obtain clear liquid water Liquid extraction; the volatile oil mixture was separated with an oil-water separator to obtain pure volatile oil, and stored with 95% ethanol at a volume rati...

Embodiment 2

[0114] A traditional Chinese medicine capsule for treating primary dysmenorrhea (syndrome of stagnation of qi stagnation and blood stasis due to cold condensate). 300 parts of medicine, 200 parts of Evodia rutaecarpa, 300 parts of Puhuang.

[0115] The preparation method of present embodiment product is:

[0116] (1) Weigh Corydalis Corydalis, Angelica, Chuanxiong, Wuyao, Evodia decoction pieces, and Puhuang according to the ratio of parts by weight, wherein Corydalis Corydalis, Angelica, Chuanxiong, and Aconitum are pulverized into coarse powder;

[0117] (2) Add 10 times the weight of water of angelica, chuanxiong, wuyao, and evodia to boil, keep boiling, and extract for 5 hours to obtain water extract, volatile oil and medicinal residue, among which the water extract is directly filtered to obtain clear liquid water Liquid extraction; the volatile oil mixture was separated with an oil-water separator to obtain pure volatile oil, and stored with 95% ethanol at a volume rati...

Embodiment 3

[0129] A traditional Chinese medicine capsule for treating primary dysmenorrhea (syndrome of stagnation of qi stagnation and blood stasis due to cold condensate). 143 parts of medicine, 111 parts of Evodia rutaecarpa, 159 parts of Puhuang.

[0130] The preparation method of present embodiment product is:

[0131] (1) Weigh Corydalis Corydalis, Angelica, Chuanxiong, Wuyao, Evodia decoction pieces, and Puhuang according to the ratio of parts by weight, wherein Corydalis Corydalis, Angelica, Chuanxiong, and Aegypti are pulverized into coarse powder;

[0132] (2) Add 10 times the weight of water of angelica, chuanxiong, wuyao, and evodia to boil, keep boiling, and extract for 5 hours to obtain water extract, volatile oil and medicinal residues, among which the water extract is directly filtered to obtain clear liquid water Extract the liquid; separate the volatile oil mixture with an oil-water separator to obtain pure volatile oil, and store it with 95% ethanol at a volume ratio ...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating primary dysmenorrheal. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 100-300 parts of Rhizoma Corydalis, 100-300 parts of angelicae sinensis, 100-200 parts of Ligusticum wallichii, 100-300 parts of combined spicebush root, 100-200 parts of fructus evodiae and 100-300 parts of cattail pollen. A preparation method of the traditional Chinese medicine composition for treating the primary dysmenorrheal comprises the following steps: (1) weighing raw materials; (2) extracting volatile oil of angelicae sinensis, Ligusticum wallichii, combined spicebush root and fructus evodiae in water, carrying out inclusion on the volatile oil by utilizing beta-cyclodextrin to obtain volatile oil inclusion compound, and obtaining water extract and medicinal dregs for standing; (3) extracting the Rhizoma Corydalis and the medicinal dregs by utilizing alcohol, and obtaining alcohol extract for standing; (4) sterilizing the cattail pollen, drying and crushing; (5) concentrating the water extract and the alcohol extract in a decompression manner; (6) uniformly mixing and drying the concentrated water extract and 3 / 4 of the cattail pollen to obtain water-extract dried cream; (7) uniformly mixing and drying the concentrated alcohol extract and 1 / 4 of the cattail pollen to obtain alcohol-extract dried cream; and (8) uniformly mixing the water-extract dried cream, the alcohol-extract dried cream and the volatile oil inclusion compound, crushing, shaping and preparing to obtain the traditional Chinese medicine composition for treating the primary dysmenorrheal. The traditional Chinese medicine composition for treating the primary dysmenorrheal has the advantages of exact curative effect, precise and simple medicine proportion, low medicine usage, good curative effect, small side effects, convenience for taking, abundant medicine source and the like.

Description

technical field [0001] The invention relates to a medicine for treating primary dysmenorrhea, in particular to a medicine preparation for menstrual abdominal pain caused by cold condensate, stagnation of qi and blood stasis, especially suitable for premenstrual or menstrual abdominal pain, Backache, menstrual blood with dark lumps, breast distending pain, chest tightness and discomfort, etc.; the invention also relates to a preparation method of the pharmaceutical preparation. Background technique [0002] Dysmenorrhea is a common and frequently-occurring disease in gynecological clinics. According to a sample survey in 1980, the incidence of dysmenorrhea in my country was 33.1%, of which primary dysmenorrhea accounted for 36.06%, and severely affected workers accounted for 13.59%. Dysmenorrhea shows effect repeatedly, brings great misery to the patient. [0003] The cause of primary dysmenorrhea has not been fully clarified in modern medicine, and it is believed to be rel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P15/00A61P29/00
Inventor 班书贤张华张琳宇赵慧民赵学刚刘会灵周桂荣
Owner HEBEI AOXING GROUP PHARMA