Application of Lycorine compound in preparation of anti-tumor drugs

A technology of anti-tumor drugs and compounds, applied in anti-tumor drugs, drug combinations, organic chemistry, etc., can solve problems such as unknown mechanism of action
CN103304573AInactive Publication Date: 2013-09-18NANKAI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANKAI UNIV
Publication Date
2013-09-18
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to application of a Lycorine compound in anti-tumor drugs, and also relates to application of its various optical isomers, pharmaceutically acceptable salts, solvates and prodrugs in preparation of anti-tumor drugs. The invention also relates to application of pharmaceutical compositions containing the Lycorine compound with a structure shown as formula (A) in preparation of anti-tumor drugs.
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Description

technical field

[0001] The present invention relates to lycorine compounds, pharmaceutical compositions, synthesis methods and preparation methods of such compounds. Specifically, the present invention provides a class of lycorine compounds, a pharmaceutical composition containing the compounds and an anti-tumor application of the compounds. Background technique

[0002] Lycoris Herb (Lycoris Herb) belongs to the monocot class Amaryllidaceae (Amarylllidaceae), and there are more than 20 species in the world. Lycoris plants have long been used as medicinal plants to treat diseases and injuries. According to the "Compendium of Materia Medica" records: Lycoris not only has multiple functions such as detoxification, expectoration, diuresis, and vomiting, but also can be used for sore throat, carbuncle, etc. Swelling sores, scrofula, edema, etc. Lycorine is an isoquinoline alkaloid, which was first isolated from the bulb of Lycoris in 1895. It has anti-inflammatory, anti-virus,...

Claims

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