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A kind of hemostatic starch and preparation method thereof

A technology of starch and modified starch, which is applied in medical science, bandages, absorbent pads, etc., can solve the problems of low water absorption and unstable preparation of modified starch, and achieve the effects of improving water absorption performance, stable preparation, and convenient preparation

Active Publication Date: 2016-03-30
江苏德威兰医疗器械股份有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] An object of the present invention is to provide a new hemostatic starch, which has good water absorption, safety, and stable performance, and overcomes the shortcomings of low water absorption and unstable preparations of modified starch in the prior art.

Method used

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  • A kind of hemostatic starch and preparation method thereof
  • A kind of hemostatic starch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Hydroxypropyl distarch phosphate is subjected to etherification, crosslinking and esterification with chemical reagents such as propylene oxide and phosphoric acid to make new modified starch, and then the modified starch slurry (ice bath) is placed in ultrasonic In the cell pulverizer, use 450w power to act for 3min (act for 2s and rest for 2s). Wash with alcohol and dry to obtain hemostatic starch 1.

Embodiment 2

[0033] The hydroxypropyl distarch phosphate slurry (ice bath) was placed in an ultrasonic cell pulverizer, and acted on with 450w power for 3min (acting for 2s and resting for 2s). Wash with alcohol, dry, and then undergo etherification, crosslinking, and esterification with chemical reagents such as propylene oxide and phosphoric acid to make new modified starch, wash with alcohol, and dry to obtain hemostatic starch 2.

Embodiment 3

[0035] The hydroxyethyl starch is subjected to etherification, cross-linking and esterification with chemical reagents such as propylene oxide and phosphoric acid to make a new modified starch, and then the modified starch slurry (ice bath) is placed in an ultrasonic cell pulverizer In the middle, use 450w power to act for 3min (act for 2s and rest for 2s). Wash with alcohol and dry to obtain hemostatic starch 3.

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Abstract

The present invention relates to hemostasis starch and applications thereof, wherein modified starch in the existing technology is subjected to denaturation again, and then is subjected to an ultrasonic treatment to finally prepare the hemostasis starch. The hemostasis starch has characteristics of excellent water absorption effect, safety, stability and biocompatibility, and can be directly used for a wound surface having blood.

Description

technical field [0001] The invention relates to a hemostatic starch and a preparation method thereof, in particular to a biocompatible hemostatic starch which can be directly used on bloody wounds and a preparation method thereof. Background technique [0002] Bleeding is the most likely phenomenon in accidents and medical treatment. A large amount of bleeding will endanger human life. Therefore, it is necessary to stop bleeding in time for bleeding wounds. [0003] With the development of medicine, there are many kinds of hemostatic materials. In terms of biocompatibility, commonly used biocompatible hemostatic materials include: absorbable gelatin starch, collagen starch and other gelatin hemostatic materials; oxidized cellulose, oxidized regeneration Cellulose hemostatic materials; chitosan / chitin, starch polysaccharides and other natural biopolysaccharide hemostatic materials, etc. [0004] The content of the present invention relates to the hemostatic material of starc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08B31/00C08B31/16A61L15/28A61L31/04
Inventor 刘泊志
Owner 江苏德威兰医疗器械股份有限公司
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