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Chinese medicine composition and preparation method thereof

A kind of composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition

Inactive Publication Date: 2013-10-09
石强
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Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Chinese medicine composition and preparation method thereof

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Experimental program
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Effect test

Embodiment approach

[0035] The first step: preparation of various extracts

[0036] (1) Preparation of concentrated extract of psyllium seedlings and longan longan decocted in water

[0037] According to the compatibility ratio of 1-4:1, take plantain seed and longan longan, soak in distilled water, heat and decoct, filter with silk cloth, add distilled water to the medicinal residue, soak, decoct and filter in the same way, mix the two filtrates, and heat Concentrate, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C.

[0038] (2) Preparation of psyllium polysaccharide

[0039] Take plantain seed, extract with NaOH solution with pH=9, filter, adjust the filtrate to neutral with dilute hydrochloric acid, concentrate, let it cool, add ethanol and place it under stirring, filter off ethanol, soak in absolute ethanol for 1h, set aside Dry it in an oven at 60°C to obtain it.

[0040] (3) Preparation of ethanol extract of Piper longum

[0041] Take longum longum, pulv...

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Abstract

The invention relates to a Chinese medicine composition, a preparation method and an application of the Chinese medicine composition in preparing a medicament for reducing toxicity and enhancing efficacy in cancer chemotherapy. The Chinese medicine composition is prepared from a boiled concentrated semen plantaginis fructus piperis longi extract, semen plantaginis polysaccharide, a fructus piperis longi ethanol extract and piperine according to a ratio of (2-6):(1-6):(3-8):(3-5). The composition has a good treatment effect on cancer chemotherapy-induced diarrhea and has an enhancing effect on cancer chemotherapy at the same time.

Description

technical field [0001] The present invention relates to a kind of traditional Chinese medicine composition, more specifically relate to a kind of traditional Chinese medicine composition that is composed of the concentrated extract of water decoction of Semen psyllium longum, polysaccharide of Semen psyllium, ethanol extract of Piper longum and piperine. The traditional Chinese medicine composition The preparation method and the use of the traditional Chinese medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs are cytotoxic anti-tumor drugs, which can cause diarrhea and o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/68A61P35/00A61P1/12A61K31/715A61K31/4525
Inventor 石强
Owner 石强
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