Application of oligomeric guluronic acid in the preparation of drugs, health products or dietary supplements for the prevention and treatment of alcoholic liver injury

A technology for polyguluronic acid and alcoholic liver injury, which is applied in the field of marine medicine, can solve the problems that have not been seen before, achieves broad development and application prospects, is easy to industrialize, and improves the effect of GSH level.
CN103446165BInactive Publication Date: 2016-04-13OCEAN UNIV OF CHINA
4 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
OCEAN UNIV OF CHINA
Publication Date
2016-04-13
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention provides application of guluronic acid oligomers in preparing medicines, health products or dietary supplements for preventing and treating alcoholic liver injury. Guluronic acid oligomers with different molecular weights, which are obtained by degrading polyguluronic acid graded and purified from algin, can lower the hepatosomatic index increase caused by alcoholic injury, resist triglyceride and cholesterol increase caused by alcohol, effectively lower glutamic-pyruvic transaminase and glutamic oxaloacetic transaminase increase in serum caused by alcohol, enhance the total oxidation resistance, glutathione level and superoxide dismutase activity in the serum, inhibit the generation of malonaldehyde in the liver caused by alcohol, lower the mouse drunkenness rate, prolong the mouse drunkenness time, and shorten the sober-up time, thereby implementing the protective action and hangover alleviating function on alcoholic hepatic injury. The products provided by the invention are derived from marine natural products, have the advantages of abundant resources, high industrialization tendency, high safety, high effectiveness and the like, and have wide development and application prospects in the aspects of prevention and treatment of alcoholic hepatic injury, hangover alleviation and liver protection.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of marine medicines, and in particular relates to the application of oligomeric guluronic acid in the preparation of medicines, health care products or dietary supplements for preventing and treating alcoholic liver damage. Background technique

[0002] Liver damage caused by excessive alcohol consumption is a worldwide medical problem. Alcoholic fatty liver (ALD) is an early manifestation of alcohol-induced liver damage, which can develop into alcoholic hepatitis, liver fibrosis, liver cirrhosis and even liver cancer. In developed countries such as Europe and the United States, alcoholic liver disease and its complications are one of the important causes of death. In recent years, the incidence of ALD in my country has also been increasing year by year, the degree of liver damage is aggravating, and the number of damaged functional organs is increasing, which has caused systemic harm to the health of the Chinese pop...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More