A hyperpolarized gas breathing device for human body under non-anesthesia state

Abstract

The invention discloses a hyperpolarization gas breathing device for a human body under a non-narcosis state. The device comprises a console (1), an I / O port (2), four electromagnetic valves (5, 8, 11 and 14), four solid-state relays (3, 7, 10 and 12), a two-way air control valve (16), a three-way direction-changing air control valve (20), three gas flow meters (4,9 and 19), two nitrogen cylinders (13 and 15), a hyperpolarization gas sampling bag (17), a sealed organic glass box (18) and an oxygen bottle (6). The console controls the solid-state relays to turn on or turn off the electromagnetic valves through the I / O port, and the electromagnetic valves turn on or turn off the air control valves to control the state of the human body each time air is breathed in and breathed out. The device is simple in structure, convenient to control and capable of enabling the human body to accurately breathing in and breathing out hyperpolarization gas in a constant size under the non-narcosis state, the human body can breathe multiple times and sampling can be carried out repeatedly.

Description

Technical field [0001] The invention belongs to the field of hyperpolarized gas magnetic resonance imaging and spectroscopy, and more specifically relates to a hyperpolarized gas breathing device, and also relates to breathing process control, which is suitable for nuclear magnetic resonance imaging and spectroscopy of hyperpolarized gas. Background technique [0002] As a non-radioactive, non-invasive imaging technology, MRI is widely used in hospitals to diagnose brain diseases, muscle injuries and other related lesions. However, it is very weak in the diagnosis of lung diseases, because the current commercial MRI machine mainly uses protons as the detection nucleus, while the lungs are mainly composed of alveolar cavity structures. The low density of protons leads to nuclear magnetic resonance. The signal of resonance is very low. Therefore, conventional MRI (magnetic resonance images using protons as the observation nucleus) cannot obtain magnetic resonance images of the lun...

AI Technical Summary

Problems solved by technology

Therefore, the volume of gas inhaled and exhaled is more difficult to control

[0006] The existing ventilator or breathing system, (1) For animals, usually after anesthesia, it is necessary to monitor the gas pressure in the lungs or give gas in a high-pressure way through a gas restrictor, so that it can passively inhale and exhale gas; ( 2) Conventional ventilators for the human body can achieve quantitative gas inhalation by the human body, but generally make the human body passively breathe through pressure, but cannot achieve the same amount of exhaled gas

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