Magnetic pirarubicin nano-drug composite

A magnetic pirarubicin and pirarubicin technology, which can be used in drug combinations, antitumor drugs, pharmaceutical formulations, etc., can solve the problems of inability to withstand perfusion chemotherapy, lack of targeting of chemotherapy drugs, and bladder epithelial cell killing, etc. To achieve the effect of good dispersion and reduce toxic and side effects
CN103536626AInactive Publication Date: 2014-01-29代宏 +1
3 Cites 2 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
代宏
Publication Date
2014-01-29
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention belongs to the field of pharmaceutical preparations, and particularly relates to a magnetic pirarubicin nano-drug composite. The magnetic pirarubicin nano-drug composite comprises pirarubicin, an Fe3O4 nanoparticle and 3-aminopropyl triethoxysilane, wherein the particle diameter of the Fe3O4 nanoparticle is 10-100 nanometers. The magnetic pirarubicin nano-drug composite disclosed by the invention has good stability and dispersity and property of being positioned to a tumour part in a targeted way through an external magnetic field and reduces the toxic side effect on a normal structure by restricting the dual inhibiting effect of THP and Fe3O4 on a cell on a specific tumour part.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a magnetic pirarubicin nanometer pharmaceutical composition and its application for treating bladder cancer. Background technique

[0002] Bladder cancer is the malignant overgrowth of cells in the bladder that develops into a malignant tumor. Worldwide, bladder cancer is the seventh most common cancer in men, causing 112,300 deaths per year. In contrast, female patients are slightly less than male patients. Bladder cancer is the most common malignant tumor of the urinary system, 90% of which are transitional cell carcinomas, about 5% are phosphorous cell carcinomas, and 2% are adenocarcinomas.

[0003] Currently, the most common treatments for bladder cancer are radical cystectomy and radiotherapy. But this treatment can cause irreversible damage to the patient, resulting in loss of organs, loss of sexual function, damage to normal tissues, etc. Therefo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More