Pharmaceutical composition having blood sugar reducing effect

A composition and hypoglycemic technology, applied in the field of medicine, can solve the problems of complex etiology and pathogenesis, lack of treatment methods for the cause, incomplete understanding, etc., and achieve high bioavailability, no toxic side effects, and total effective rate. high effect

Inactive Publication Date: 2014-02-12
HAIMEN ZHUOWEI TEXTILE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, the etiology and pathogenesis of this disease are complicated and have not been fully understood so far, and there is even a lack of effective methods for treating the etiology.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A pharmaceutical composition for treating diabetes, which is prepared from the following raw materials,

[0027] 30 parts of astragalus, 28 parts of gorgon, 28 parts of golden cherry, 27 parts of dodder, 27 parts of burdock root, 25 parts of Anemarrhena, 25 parts of Chinese yam, 25 parts of Imperata rhizome, 23 parts of angelica, 23 parts of chrysanthemum, 20 parts of purslane, 20 parts of Danshen, 20 parts of Ophiopogon japonicus, 17 parts of ginseng, 17 parts of herb, 15 parts of mulberry leaves, 15 parts of dendrobium, 15 parts of japonica rice, 15 parts of medlar, 15 parts of trichosanthes, 10 parts of red peony, 10 parts of ginger, dogwood 10 parts, 9 parts of raspberry, 9 parts of Polygonatum odoratum, 9 parts of myrrh, 9 parts of kudzu root, 5 parts of Chuanxiong, 5 parts of Rehmannia glutinosa, and 5 parts of Schisandra.

[0028] The preparation and taking method of the above-mentioned pharmaceutical composition are as follows: take the raw material drug (propor...

Embodiment 2

[0034] zoology experiment

[0035] Experimental animals: 50 wistar rats, male, (180±10) g, provided by the Animal Center of Linyi People's Hospital. After the rats were adapted to feeding in the animal room for 3 days, 10 rats were randomly selected as the normal control group and fed with ordinary maintenance feed. High-sugar and high-fat feed formula: rat basic feed 68%, sucrose 10%, egg yolk powder 9%, lard 8%, cholesterol 1%, bile salt 0.2%.

[0036]Implementation method: the remaining 40 were fed with high-sugar and high-fat feed for 4 weeks. Four weeks later, rats were fasted for 18 hours, and streptozotocin (STZ) was injected intravenously at 20 mg / Kg once every two days. Select 30 rats with successful modeling, and randomly divide them into 3 groups, 10 in each group, i.e. model group (without administering any drug), drug group of Example 1 of the present invention 10 mg / Kg, control drug group: administer Glicheide (10mg / kg), the way of administration is oral, take...

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PUM

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Abstract

The invention relates to a pharmaceutical composition having a blood sugar reducing effect. The pharmaceutical composition is prepared from the following raw materials: astragalus membranaceus, gorgon fruit, fructus rosae laevigatae, seed of Chinese dodder, burdock root, rhizoma anemarrhenae, yam, lalang grass rhizome, angelica, chrysanthemum, purslane, root of red-rooted salvia, radix ophiopogonis, ginseng, rhizoma atractylodis, folium mori, dendrobe, polished round-grained rice, medlar, root of Chinese trichosanthes, root of common peony, baked ginger, dogwood, raspberry, radix polygonati officinalis, myrrh, root of kudzu vine, ligusticum wallichii, prepared rehmannia root and fruit of Chinese magnoliavine. The pharmaceutical composition has high effective rate on diabetes and avoids relapse after curing; the pharmaceutical composition is simple in process, can low production cost and relieve economic burden of patients, and has a broad application prospect.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition with hypoglycemic effect and a preparation method. Background technique [0002] Diabetes is an endocrine and metabolic disease characterized by hyperglycemia. Sugar, protein, fat, water and A series of metabolic disorder syndromes such as electrolytes, clinically characterized by hyperglycemia, typical cases may show polyuria, polydipsia, polyphagia, weight loss, etc. If it is not good, it will cause complications, leading to failure and lesions in the kidneys, eyes, feet and other parts, and it cannot be cured. [0003] Diabetes can be divided into type 1 diabetes and type 2 diabetes according to the pathogenesis. Type 1 diabetes accounts for less than 10% of diabetes, and is mainly dependent on insulin therapy, which means that insulin therapy is required from the beginning of the disease, and it will be used for life; the reason is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P3/10
Inventor 李涛王永翠宋仪利
Owner HAIMEN ZHUOWEI TEXTILE CO LTD
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