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Medicine for treating Alzheimer disease and preparation method thereof

A technology for senile dementia and drugs, which is applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., and can solve problems such as curative effects that need to be further confirmed

Active Publication Date: 2014-04-30
GUIZHOU SHENQI PHARMA RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Huperzine A is a huperzine alkaloid isolated from Chinese herbal medicine. It is a natural cholinesterase inhibitor. It has been used clinically in my country, but its efficacy needs to be further confirmed.

Method used

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  • Medicine for treating Alzheimer disease and preparation method thereof
  • Medicine for treating Alzheimer disease and preparation method thereof
  • Medicine for treating Alzheimer disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] Formula: 30g of artificial stem cells, 30g of human fetal membranes, 30g of Melaleuca extract, and 10g of DHA.

[0085] Technology: prepare according to the following steps:

[0086] A. Weigh 20 times the amount of lecithin and 5 times the amount of cholesterol in the stem cells, put them in a round bottom flask, add 50 times the amount of absolute ethanol to dissolve the stem cells, and remove the absolute ethanol by rotary evaporation in a water bath at 40°C to make the lipids in the container A layer of uniform film is formed on the wall for later use; take stem cells and put them into a solution containing complete stem cell culture medium, move them to the above-mentioned rotary evaporator with a thin film, hydrate for 30 minutes, and ultrasonicate for 15 minutes with an ice-water bath probe to obtain stem cell lipids. Plastid suspension, the suspension was frozen at -20°C for 24 hours, then thawed at room temperature and then frozen at -20°C for 24 hours, repeated...

Embodiment 2

[0092] Formula: 50g of artificial stem cells, 50g of human fetal membranes, 50g of Melaleuca extract, and 20g of DHA.

[0093] Technology: prepare according to the following steps:

[0094] A. Weigh 20 times the amount of lecithin and 5 times the amount of cholesterol in the stem cells, put them in a round bottom flask, add 50 times the amount of absolute ethanol to dissolve the stem cells, and remove the absolute ethanol by rotary evaporation in a water bath at 40°C to make the lipids in the container A layer of uniform film is formed on the wall for later use; take stem cells and put them into a solution containing complete stem cell culture medium, move them to the above-mentioned rotary evaporator with a thin film, hydrate for 30 minutes, and ultrasonicate for 15 minutes with an ice-water bath probe to obtain stem cell lipids. Plastid suspension, the suspension was frozen at -20°C for 24 hours, then thawed at room temperature and then frozen at -20°C for 24 hours, repeated...

Embodiment 3

[0100] Formula: 10g of artificial stem cells, 10g of human fetal membranes, 10g of Melaleuca extract, 5g of DHA.

[0101] Technology: prepare according to the following steps:

[0102] A. Weigh 20 times the amount of lecithin and 5 times the amount of cholesterol in the stem cells, put them in a round bottom flask, add 50 times the amount of absolute ethanol to dissolve the stem cells, and remove the absolute ethanol by rotary evaporation in a water bath at 40°C to make the lipids in the container A layer of uniform film is formed on the wall for later use; take stem cells and put them into a solution containing complete stem cell culture medium, move them to the above-mentioned rotary evaporator with a thin film, hydrate for 30 minutes, and ultrasonicate for 15 minutes with an ice-water bath probe to obtain stem cell lipids. Plastid suspension, the suspension was frozen at -20°C for 24 hours, then thawed at room temperature and then frozen at -20°C for 24 hours, repeated free...

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Abstract

The invention discloses a medicine for treating Alzheimer disease. The medicine is prepared from artificial stem cells, human embryolemma, lycopodium serratum extracts, DHA and auxiliary materials. The medicine for treating Alzheimer disease has the functions of aging prevention and memory enhancement, is definite in curative effect, small in side effect, gentle in medicine efficacy obligation, and is applicable to being taken for a long term.

Description

technical field [0001] The invention relates to a medicine for treating senile dementia and a preparation method thereof, belonging to the field of medicine technology. technical background [0002] Alzheimer's disease (AD), also known as senile dementia, is a degenerative disease of the central nervous system with an insidious onset and a chronic progressive course. It is the most common type of senile dementia. The main manifestations are neuropsychiatric symptoms such as progressive memory impairment, cognitive dysfunction, personality changes, and language barriers, which seriously affect social, occupational, and life functions. Its prevalence rate increases with age, about 5% in people over 65 years old, and about 20% in people over 85 years old. The disease is often sporadic, and there are more women than men, and the course of the disease in women is often longer than that in men. With the aging of the population, the incidence of AD is increasing year by year, whi...

Claims

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Application Information

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IPC IPC(8): A61K36/11A61K9/127A61K9/20A61K9/48A61K9/16A61P25/28A61K35/54A61K35/12A61K35/50A61K35/545
Inventor 张芝庭张涛涛
Owner GUIZHOU SHENQI PHARMA RES INST
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