Traditional Chinese medicine composition for being diuretic and protecting liver and preparation method of composition

A composition and technology of traditional Chinese medicine, applied in the field of diuretic and liver-protecting traditional Chinese medicine composition and its preparation, can solve the problems of affecting drug efficacy, unable to extract active ingredients, low extraction rate, etc., achieve the reduction of stem cell degeneration, significant liver protection effect, The effect of improving liver function

Inactive Publication Date: 2014-04-30
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] Due to the different properties of the active ingredients in the eight-flavored medicinal materials, if the preparation methods in the above patents all use water extraction, some active ingredients cannot be extracted, or the extraction rate is low, which will affect the efficacy of the drug.

Method used

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  • Traditional Chinese medicine composition for being diuretic and protecting liver and preparation method of composition
  • Traditional Chinese medicine composition for being diuretic and protecting liver and preparation method of composition
  • Traditional Chinese medicine composition for being diuretic and protecting liver and preparation method of composition

Examples

Experimental program
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Effect test

Embodiment 1

[0075] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0076] 2) Add 0.1% mass-volume citric acid solution to extract twice, adding citric acid solution 20 times and 15 times the total weight of medicinal materials respectively, each extraction time is 4 hours and 2 hours respectively, Combine the extracts, filter, and concentrate the filtrate into a liquid extract;

[0077] 3) The corn silk, plantain, and sea ginseng are extracted twice with ethanol with a volume percentage of 60%. Each time, 12 times and 8 times the total weight of the two herbs are added with ethanol, and the extraction time is 5 times respectively. hour, 3 hours, combine the extracts, filter, recover the medicinal residues, and concentrate the filtrate into a liquid extract;

[0078] 4) In step 3), the res...

Embodiment 2

[0081] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0082] 2) Extract citric acid solution with a mass-volume percentage of 1% of Jigucao for 3 times, adding 20 times, 15 times, and 8 times the total weight of the medicinal materials each time, and the extraction time is 4 hours, After 2 hours and 1 hour, the extracts were combined, filtered, and the filtrate was concentrated into a liquid extract;

[0083] 3) The corn silk, plantain, and sea ginseng are extracted three times with ethanol with a volume percentage of 80%. Each time, 12 times, 8 times, and 6 times the total weight of the two herbs are added, and the extraction time for each time is 3 hours, 3 hours, and 1 hour respectively, combine the extracts, filter, recover the medicinal residues, and concentrate the filtr...

Embodiment 3

[0087] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0088] 2) Extract citric acid solution with mass-volume percentage of 0.5% of Jigucao for 3 times, adding 20 times, 15 times and 10 times of the total weight of medicinal materials respectively, each time for 3 hours, 10 times and 10 times respectively. After 2 hours and 1 hour, the extracts were combined, filtered, and the filtrate was concentrated into a liquid extract;

[0089] 3) The corn silk, plantain, and sea ginseng are extracted three times with ethanol with a volume percentage of 70%. Each time, 10 times, 8 times, and 8 times the total weight of the two herbs are added, and the extraction time for each time is 4 hours, 3 hours, and 2 hours respectively, combine the extracts, filter, recover the medicinal residues,...

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Abstract

The invention relates to a traditional Chinese medicine composition for being diuretic and protecting liver and a preparation method of the composition. The preparation method of the traditional Chinese medicine composition disclosed by the invention mainly comprises the following steps of taking medicinal materials including desmodium styracifolium, corn stigma, pyrrosia lingua, abrus cantoniensis hance, poria cocos, plantain herb, lygodium japonicum sw and lalang grass rhizome, extracting abrus cantoniensis hance by using acid aqueous solution, after extracting corn stigma, plantain herb and lygodium japonicum sw by using high-concentration ethanol, mixing alcohol extraction decoction dregs of corn stigma, plantain herb and lygodium japonicum sw with desmodium styracifolium, pyrrosia lingua, lalang grass rhizome and poria cocos, carrying out aqueous extraction together, finally, mixing decoction through three extraction methods, and then, obtaining fluid extract. By means of animal pharmacological experiments and clinical experiments, the results prove that the diuretic and liver-protecting effect of the traditional Chinese medicine composition provided by the invention is prior to that in the prior art while treating lithiasis in the urinary system.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating urinary calculi, in particular to a diuretic and liver-protecting traditional Chinese medicine composition and a preparation method thereof. Background technique [0002] Urinary system stones belong to the scope of "sand stranguria", "stone stranguria" and "blood stranguria" in TCM gonorrhea, mainly including 4 syndrome types: [0003] (1) Qi stagnation and blood stasis type: Symptoms include dull pain in the lower back, dull pain, normal or tight pulse, and normal tongue; or sudden interruption of urination during drowning, severe pain that extends to the waist and abdomen, and the pain is relieved after the discharge of sand and stones; or Pain in the waist and flanks that is like twisting, causing the lower abdomen, frequent attacks, pale complexion, cold sweat, nausea, accompanied by blood in the urine or yellowish urine, dark red tongue or petechiae, ecchymosis, stri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P13/04A61P7/10A61P1/16
Inventor 林艳英张栩颜刘冠萍郑志远钟杰敏陈瑛梁云飞
Owner GUANGXI WUZHOU PHARMA GRP
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