A traditional Chinese medicine mixture capable of delaying skin ageing, a preparation method thereof and applications thereof
A skin aging, traditional Chinese medicine technology, applied in skin care preparations, skin diseases, drug combinations, etc., can solve problems such as unsatisfactory effects and irritating anti-aging products, and achieve the effect of delaying skin aging
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Embodiment 1
[0021] (1) Mix 150g Codonopsis pilosula, 300g Astragalus membranaceus, and 100g Poria cocos, soak in water with 12 times the crude drug amount for 1 hour, decoct at 180°C for 30 minutes, filter out the decoction, add 8 times the amount of crude drug amount of water to decoct at 200°C Cook for 60 minutes, filter out the decoction, and combine the two decoctions;
[0022] (2) To the combined decoction obtained in step (1), add 50 g of Herba Eustonia powder with a particle size of 20 meshes, and extract twice at 100°C under reflux with water, each time for 3 hours. After the extract is concentrated under reduced pressure, add Absolute ethanol, precipitate overnight at 4°C to 20°C, and take the filtrate;
[0023] (3) Melt 50 g of donkey-hide gelatin with hot water of 5 times the amount of the crude drug, add animal proteolytic enzymes with 6% of the mass of donkey-hide gelatin, hydrolyze the enzyme at 55-60 ° C, pH 6.0 for 5 hours, and obtain the donkey-hide gelatin raw material; ...
Embodiment 2
[0026] (1) Mix 500g Codonopsis pilosula, 200g Astragalus root, and 200g Poria cocos, soak in water with 8 times the crude drug amount for 1 hour, decoct at 200°C for 30 minutes, filter out the decoction, add 8 times the crude drug amount of water to decoct at 180°C Cook for 60 minutes, filter out the decoction, and combine the two decoctions;
[0027] (2) To the combined decoction obtained in step (1), add 100 g Eustonia powder with a particle size of 20 meshes, extract twice at 100° C. with water under reflux, each time for 3 hours, and concentrate the extract under reduced pressure , add absolute ethanol, precipitate overnight at 4°C, and take the filtrate;
[0028] (3) Melting 100 g of donkey-hide gelatin with 8 times the crude drug amount of hot water, adding animal proteolytic enzymes with 6% of the mass of donkey-hide gelatin, hydrolyzing at 55 ° C, pH 7.0 for 3 hours, and then inactivating the enzyme to obtain the donkey-hide gelatin raw material;
[0029] (4) The filt...
Embodiment 3
[0031] (1) Mix 150g Codonopsis pilosula, 300g Astragalus membranaceus, 100g Poria cocos, 100g angelica and 10g safflower, soak in water with 8 times the crude drug amount for 1 hour, decoct at 200°C for 60 minutes, filter out the decoction, and add 6 times to the filter residue Decoct the amount of crude drug in water at 180°C for 30 minutes, filter out the decoction, and combine the two decoctions;
[0032] (2) To the combined decoction obtained in step (1), add 50 g of Herba Eustoma powder with a particle size of 20 meshes, extract twice at 100° C. with water under reflux, each time for 3 hours, and concentrate the extract under reduced pressure , add absolute ethanol, precipitate overnight at 20°C, and take the filtrate;
[0033] (3) Melt 50 g of donkey-hide gelatin with hot water of 5 times the amount of the crude drug, add animal proteolytic enzymes with 6% of the mass of donkey-hide gelatin, hydrolyze the enzyme at 55-60 ° C, pH 7.0 for 5 hours, and obtain the raw materi...
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