Unlock instant, AI-driven research and patent intelligence for your innovation.
Preparation method of pidotimod dry suspension
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A technology of dry suspension and dry suspension of pidotimod, which is applied in the field of preparation of dry suspension of pidotimod, can solve the problems of a single unfavorable clinical application of pidotimod preparation, and achieve stability, Fast and effective in solving taste problems
Inactive Publication Date: 2014-06-04
QINGDAO BOITE BIOPHARM
View PDF0 Cites 1 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
[0004] The present invention has designed a kind of preparation method of pidotimod dry suspension, overc
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Examples
Experimental program
Comparison scheme
Effect test
preparation example Construction
[0005] The preparation method step of pidotimod dry suspension in the present invention is as follows:
[0006] 1. Pass pidotimod, starch, mannitol, sodium citrate, and sodium chloride through a 100-mesh sieve respectively, weigh according to the prescription amount, and mix well;
[0007] 2. Add 50% ethanol to soften, granulate with a 20-mesh sieve, dry at 60°C, and granulate with a 30-mesh sieve;
[0008] 3. Add tragacanth gum, apple essence, and aspartame, mix well, and you get it.
[0009] The present invention is further illustrated below in conjunction with specific examples.
Embodiment 1
[0011] After passing pidotimod, starch, mannitol, sodium citrate, and sodium chloride through a 100-mesh sieve, weigh 40g of pidotimod, 180g of starch, 25g of mannitol, 100g of sodium citrate, and 10g of chloride Sodium, add an appropriate amount of 50% ethanol to soften, granulate with a 20-mesh sieve, and granulate with a 30-mesh sieve after drying at 60°C. Add 1.6g tragacanth gum, 5g aspartame, 0.5g apple essence, and mix well.
[0012] After screening aspartame, cyclamate, banana essence, apple essence, orange essence, sodium citrate, sodium chloride and other flavoring agents, it was found that aspartame, apple essence, citron The mixed powder of sodium chloride and sodium chloride is better as a flavoring agent, not only the prepared pidotimod dry suspension has a good taste, but also contributes to the stability of the preparation.
[0013] The pidotimod dry suspension of the present invention, by selecting specific auxiliary materials and proportioning, the prepared p...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More
PUM
Login to View More
Abstract
The invention provides a preparation method of a pidotimod dry suspension, which consists of pidotimod and accessories, wherein the accessories include a flavoring agent, a filling agent and a suspending agent. The pidotimod dry suspension has relatively bad mouthfeel so as to be not good for the administration treatment of animals. In the method provided by the invention, by adopting a specific flavoring agent and mixing at a corresponding proportion, the problem in the mouthfeel of the pidotimod dry suspension is solved perfectly; moreover, the pidotimod dry suspension takes an effect quickly, and the effect of stability of the pidotimod dry suspension is facilitated.
Description
technical field [0001] The invention belongs to the field of veterinary drug preparations and relates to a preparation method of pidotimod dry suspension. Background technique [0002] Pidotimod acts by stimulating and regulating cell-mediated immune responses, and is widely used in recurrent respiratory tract infections, urinary tract infections, and gynecological infections caused by hypocellular immune function. It can reduce the number of acute attacks, reduce the degree of attack, and can also be used as an adjuvant treatment of antibiotics in acute infections. Pidotimod can promote the phagocytic activity of macrophages and neutrophils, improve their chemotaxis; activate natural killer cells; oral and intramuscular injection has good bioavailability, can not only promote non-specific immune response, but also Promotes a specific immune response. [0003] Both animal experiments and clinical trials have shown that pidotimod has no direct antibacterial and antivi...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to View More 
Login to View More