Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Traditional Chinese medicine composition for treating liver-kidney deficiency type motor neuron disease and preparation method thereof

A technology for motor neuron disease, liver and kidney loss, applied in drug combinations, nervous system diseases, medical formulas, etc., can solve problems such as immaturity, ineffectiveness, and aggravation of the disease, and achieve rapid onset, definite curative effect, and less recurrence Effect

Inactive Publication Date: 2014-06-18
胡海波
View PDF1 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because ALS is a type of neurodegenerative disease, surgical treatment is ineffective or even aggravated
In addition, some new treatments such as stem cell transplantation and gene therapy are still in the research stage and are not yet mature for clinical use.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Example 1 Patches

[0077] Codonopsis 2900g, Yam 2500g, Ziheche 4000g, Astragalus 3000g, Angelica 3400g, Rehmannia glutinosa 3200g, Cornus officinalis 2200g, Curculigo 2800g, Eucommia 3600g, Cistanche 3000g, Chive seeds 2500g, Dendrobium 4000g, Achyranthes bidentata 5000g, Eclipta 3800g, tortoise shell 2900g, Polygonum multiflorum 2500g, Barley ginseng 2000g, Raspberry 3500g, Mulberry 2400g, Shayuanzi 23000g, Chicken liver 3500g, Magnet 3000g, Heather leaf 3500g, Millipeda 3000g and Licorice 2000g;

[0078] Its preparation method is:

[0079] a. Put the raw material drug into 3 times the amount of ethanol and heat and extract twice, use it for 1.5 hours each time, filter to obtain the filtrate 1 and medicinal residues; b, add water to the medicinal residues obtained in step a, heat and reflux twice , filter for 2 hours each time to obtain filtrate 2; c, combine the filtrate 1 and filtrate 2 into a vacuum concentration tank, reduce the pressure to 0.05-0.11MPa, and keep...

Embodiment 2

[0081] Example 2 Capsules

[0082] Codonopsis 2500g, Yam 4500g, Ziheche 2600g, Astragalus 3400g, Angelica 5000g, Rehmannia glutinosa 3000g, Cornus officinalis 2900g, Curculigo 2500g, Eucommia 3000g, Cistanche 4000g, Chive seeds 2800g, Dendrobium 3800g, Achyranthes bidentata 3600g, Eclipta 4200g, tortoise shell 4300g, Polygonum multiflorum 2500g, Barley ginseng 2000g, Raspberry 3500g, Mulberry 2400g, Shayuanzi 2300g, Chicken liver 3500g, Magneto 3000g, Heather leaf 3500g, Millipede 2600g and Licorice 3100g;

[0083] Its preparation method is:

[0084] a. Add 2 times the amount of 87% ethanol to the crude drug and soak for 2 hours, heat and extract for 1 hour, filter the supernatant and concentrate it into extract 1, and use the dregs for later use;

[0085] b. Soak the dregs obtained in step a with water for 1 hour, extract 2 times, each time for 1 hour, combine the extracts, filter through 160 mesh, centrifuge at 11000 rpm to obtain the supernatant, and then pass the cut-off ...

Embodiment 3

[0088] Example 3 liniment

[0089] Codonopsis 2800g, Yam 3400g, Ziheche 3900g, Astragalus 4500g, Angelica 5000g, Rehmannia glutinosa 3000g, Cornus officinalis 2400g, Curculigo 3200g, Eucommia 5000g, Cistanche 4000g, Chive seeds 2500g, Dendrobium 4000g, Achyranthes bidentata 3500g, Eclipta 2800g, tortoise shell 4500g, Polygonum multiflorum 2500g, Barley ginseng 2000g, Raspberry 3500g, Mulberry 2400g, Shayuanzi 2300g, Chicken liver 3500g, Magneto 3000g, Heather leaf 3500g, Millipeda 3000g and Licorice 4500g;

[0090] The preparation method of described liniment is:

[0091] In the first step, soak the Codonopsis pilosula, yam, and purple river car with 7 times the amount of ethanol for 2 hours, and extract twice at 86°C for 2 hours each time; mix the extracts twice and heat and concentrate to 90°C When the relative density is 1.01 concentrated solution, put it aside for later use;

[0092] The second step, astragalus, angelica, rehmannia, dogwood, curculigo, eucommia, cistanch...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a traditional Chinese medicine composition for treating a liver-kidney deficiency type motor neuron disease. The traditional Chinese medicine composition is prepared from the following raw medicines: codonopsis pilosula, Chinese yam, human placenta, astragalus membranaceus, angelica sinensis, prepared rhizome of rehmannia, dogwood, rhizoma curculiginis, the bark of eucommia, herba cistanche, semen allii tuberosi, dendrobe, the root of bidentate achyranthes, eclipta, tortoise shell, polygonum multiflorum, stellariayunnanensis Franch, raspberry, mulberry, flatstem milkvetch seed, chicken liver, magnetite, Chinese photinia leaf, caulis spatholobi and liquorice. The traditional Chinese medicine composition disclosed by the invention has the effects of nourishing liver and kidneys, nourishing yin and clearing away heat and is mainly used for treating long-term yin deficiency affecting yang caused by the liver-kidney deficiency type motor neuron disease. Prepared from the traditional Chinese medicinal materials with different properties according to a rigorous formula, the traditional Chinese medicine composition plays a direct effect on a focus of infection, and is short in healing period, good in curative effect and less in disease relapse possibility after the disease is cured; moreover, the traditional Chinese medicine composition is simple and convenient to prepare in a preparation process, small in toxic and side effects and convenient to take; the medicament is easy to prepare and low in cost.

Description

[0001] technical field [0002] The invention relates to a medical preparation containing raw materials derived from plants, animals or minerals, in particular to a traditional Chinese medicine composition for treating liver and kidney deficiency motor neuron disease and a preparation method thereof. [0003] Background technique [0004] Motor neuron disease (MND) is a group of chronic progressive neurodegenerative diseases of unknown etiology that selectively invade spinal cord anterior horn cells, brainstem motor neurons, cortical pyramidal cells and pyramidal tracts. The incidence rate is about 1-3 / 100,000 per year, and the prevalence is 4-8 / 100,000 per year. Since most patients die within 3-5 years after onset of symptoms, the prevalence and incidence of the disease are relatively close. [0005] The etiology of MND is still unclear, but it is generally believed that it is caused by the exposure of genetically susceptible individuals to adverse environments with age, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/8984A61P25/28A61K35/56A61K35/50A61K35/407A61K33/26A61K35/57A61K35/586
Inventor 胡海波
Owner 胡海波
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com