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A pharmaceutical composition for treating chronic renal failure, its preparation method and application
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A technology for renal function and composition, which is applied in the field of pharmaceutical compositions for treating chronic renal failure, can solve the problems of high dosage, difficult control of compound impurities, and high cost of drug use, and achieves simple preparation method, low cost of drug use, and good treatment. effect of action
Inactive Publication Date: 2016-07-06
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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Zipinggan Jiangya Drink (Zihuigan Jiangya Drink: Chinese yam, rehmannia glutinosa, Poria cocos, paeonol, Eucommia, mulberry, Achyranthes bidentata, Gastrodia elata, Uncaria, chrysanthemum, Prunella vulgaris, Cassia chinensis, mother-of-pearl, Raw rhubarb) has been shown to have a good therapeutic effect on chronic renal failure through preliminary clinical trials, but the dosage of this prescription is large, the cost of medication is high, and it is difficult to control the impurities of the compound recipe during industrialization, so further research is needed. The party conducts in-depth research
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Embodiment 1
[0024] Weigh raw materials Uncaria 15g, Chrysanthemum 15g, Poria cocos 10g, Gastrodia elata 10g, Prunella vulgaris 10g, Chinese yam 5g, Rehmannia glutinosa 5g, Cortex Moutan 5g, add auxiliary materials starch 70g to granulate, magnesium stearate 5g, dextrin 60g, microcrystalline 50g of cellulose was prepared into granules uniformly, and compressed into tablets to obtain tablets.
Embodiment 2
[0026] Weigh raw material Uncaria 80g, chrysanthemum 80g, Poria cocos 70g, Gastrodia elata 70g, Prunella vulgaris 70g, Chinese yam 50g, Rehmannia glutinosa 50g, Moutan cortex 50g, add auxiliary materials starch 500g to granulate, magnesium stearate 50g, dextrin 400g, microcrystalline 400g of cellulose was prepared into granules uniformly, and compressed into tablets to obtain tablets.
Embodiment 3
[0028] Weigh raw materials Uncaria 20g, Chrysanthemum 20g, Poria cocos 15g, Gastrodia elata 15g, Prunella vulgaris 15g, Chinese yam 10g, Rehmannia glutinosa 10g, Cortex Moutan 10g, add auxiliary materials 110g starch for granulation, magnesium stearate 10g, dextrin 100g, microcrystalline Cellulose 100g is prepared into granules uniformly, and compressed into tablets to obtain tablets.
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Abstract
The invention discloses a drug combination for treating chronic renal failure. The drug combination is prepared from the raw materials in parts by weight: 15-80 parts of uncaria, 15-80 parts of chrysanthemum, 10-70 parts of poria cocos, 10-70 parts of rhizoma gastrodiae, 10-70 parts of prunella vulgaris, 5-50 parts of yam, 5-50 parts of prepared radix rehmanniae and 5-50 parts of cortex moutan. The invention also discloses a preparation method and a purpose of the drug combination. The drug combination is simple in composition, is novel in a formula and has the characteristics of low cost, good curative effect, non toxic and side effects, difficulty in generation of tolerance, convenience in taking and carrying and general suitability for patients with the chronic renal failure.
Description
technical field [0001] The invention relates to a pharmaceutical composition for treating chronic renal failure and a preparation method thereof. Background technique [0002] Chronic renal failure (Chronic renal failure, CRF) is a syndrome composed of decreased glomerular filtration rate (GRF) caused by chronic kidney disease and related metabolic disorders and clinical symptoms. Chronic renal failure belongs to the category of "closed case", "refractory closure", "consumption" and "drug addiction" in Chinese medicine. The condition is critical and there is no specific treatment. Traditional Chinese medicine believes that this disease is a syndrome of deficiency in origin and excess in superficiality. Deficiency in origin is mainly due to weakness of kidney qi, and excess in superficiality is mainly due to dampness, turbidity and stasis. Liver and kidney are of the same source, and kidney qi is weak, leading to hyperactivity of liver yang, liver failure to drain, inability...
Claims
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Application Information
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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61P13/12
Inventor 梅建伟贾波张川峰张英强
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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