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Chitosan antibacterial gel and preparation method thereof

A technology of chitosan and gel, which is applied in the field of chitosan antibacterial gel and its preparation, can solve the problems of bacterial resistance and drug resistance, human body trauma, repeated inflammation, etc., and achieve good lubricating effect and sliding performance Good, long wetting time effect

Active Publication Date: 2014-07-16
GUANGXI XINYE BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drugs used for gynecological inflammation on the market have the following problems: 1. The environment of the reproductive tract and the self-secretion function of the mucous membrane are damaged, which leads to the decline of the local immunity of the reproductive tract and causes the pathogenic bacteria to develop drug resistance and drug resistance. , leading to repeated attacks of inflammation; 2. Trauma to the human body, destroying the secretion function of the cervix, resulting in a decrease in vaginal resistance, seriously affecting sexual life and reproductive health

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] A chitosan antibacterial gel, every liter of chitosan antibacterial gel comprises the following raw materials:

[0082] Modified Chitosan 30g

[0083] Carbomer 2.5 g

[0084] Alum 1.8 g

[0085] Glycerin 2g

[0086] Lactic acid 0.3g

[0087] Menthol 0.1g

[0088] Sodium Carboxymethyl Cellulose 2g.

[0089] The modified chitosan is chitosan hydrochloride with a degree of deacetylation of 70%.

[0090] A preparation method of chitosan antibacterial gel, it comprises the following preparation steps:

[0091] Step A, take each raw material by weight percentage, standby;

[0092] Step B, adding sodium carboxymethyl cellulose and carbomer to purified water respectively to make them fully swell to obtain sodium carboxymethyl cellulose swollen body and carbomer swollen body for later use;

[0093] Step C, dissolving modified chitosan, alum and menthol respectively, then mixing with glycerin and lactic acid, stirring evenly to obtain a mixed solution;

[0094] Step D, a...

Embodiment 2

[0096] A chitosan antibacterial gel, every liter of chitosan antibacterial gel comprises the following raw materials:

[0097] Modified Chitosan 15g

[0098] Carbomer 7g

[0099] Alum 1.4g

[0100] Glycerin 10g

[0101] Lactic acid 5g

[0102] Menthol 0.5g

[0103] Sodium Carboxymethyl Cellulose 5g.

[0104] The modified chitosan is chitosan hydrochloride with a degree of deacetylation of 95%.

[0105] This chitosan antibacterial gel also comprises the plant extract of 6g, and described plant extract comprises the raw material of following weight portion:

[0106] Treats 30 servings

[0107] Cimicifuga 20 parts

[0108] 10 parts white fresh skin

[0109] Radix Paeoniae Alba 10 parts

[0110] Sophora flavescens 20 parts

[0111] Cnidium 10 servings

[0112] Smilax 20 parts,

[0113] Add purified water to the above-mentioned raw materials for refining, filter the filtrate, concentrate and dry to obtain the plant extract.

[0114] A preparation method of chitosan an...

Embodiment 3

[0120] A chitosan antibacterial gel, every liter of chitosan antibacterial gel comprises the following raw materials:

[0121] Modified Chitosan 25g

[0122] Carbomer 8 g

[0123] Alum 1 g

[0124] Glycerin 25g

[0125] Lactic acid 6 g

[0126] Menthol 0.6g

[0127] Sodium Carboxymethyl Cellulose 6g.

[0128] The modified chitosan is carboxymethyl chitosan with a carboxylation degree of 80%.

[0129] This chitosan antibacterial gel also comprises the plant extract of 4g, and described plant extract comprises the raw material of following weight portion:

[0130] Treats 45 parts

[0131] Cimicifuga 30 parts

[0132] 25 servings of fresh white skin

[0133] Radix Paeoniae Alba 15 parts

[0134] Sophora flavescens 30 parts

[0135] Cnidium 20 parts

[0136] Smilax 30 parts,

[0137] Add purified water to the above-mentioned raw materials for refining, filter the filtrate, concentrate and dry to obtain the plant extract.

[0138] A preparation method of chitosan anti...

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Abstract

The invention relates to the technical field of antibacterial gel, in particular to chitosan antibacterial gel and a preparation method thereof. Each liter of the chitosan antibacterial gel comprises the following raw materials by weight: 5-30g of modified chitosan, 2.5-10g of carbomer, 1-1.8g of alum, 2-40g of glycerol, 0.3-10g of lactic acid, 0.1-0.8g of menthol and 2-8g of sodium carboxymethylcellulose. The chitosan antibacterial gel which is good in curative effect, can be used for preventing relapse of inflammation and is harmless to human body is prepared by using the synergistic effect of modified chitosan serving as a major raw material as well as carbomer, alum, glycerol, lactic acid and sodium carboxymethylcellulose serving as auxiliary materials, and is suitable for preventing, treating and nursing various vaginal bacterial infections, trichomonas infections, mixed infections, vulvitis, leucorrhea, candidal infection as well as wound infections of cervix uteri, genital tract and mucous membrane. By using the chitosan antibacterial gel, wound healing after physical treatment of cervical erosion is promoted, and nursing of vaginal dryness as well as cross infections in sexual intercourse and the like is improved.

Description

technical field [0001] The invention relates to the technical field of biomedical gel, in particular to a chitosan antibacterial gel and a preparation method thereof. Background technique [0002] Gynecological diseases are common diseases of women, such as vaginitis, cervicitis, pelvic inflammatory disease and other common gynecological clinical diseases, which are generally caused by bacterial infection. This type of condition is longer, and the condition shows effect repeatedly, and the condition is more stubborn, which has a strong impact on women's physical and mental health and life and work. [0003] At present, there are many kinds of medicines for the treatment of gynecological inflammation, mainly divided into suppositories, lotions, sprays and effervescent tablets. However, the drugs used for gynecological inflammation on the market have the following problems: 1. The environment of the reproductive tract and the self-secretion function of the mucous membrane are...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/896A61K9/06A61P15/00A61P31/04A61P33/02A61K33/06A61K31/722A61K31/045
Inventor 梁奕福
Owner GUANGXI XINYE BIOLOGICAL TECH
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