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Traditional Chinese medicine oral preparation for treating systemic lupus erythematosus

An oral preparation, the technology of lupus erythematosus, applied in the field of traditional Chinese medicine, can solve the problems of exacerbation of the disease, hormones that are unfavorable to the physical and mental health of patients, sudden deterioration, etc., and achieve the effects of controlling the disease, reducing the dependence on exogenous hormones, and reducing the dosage

Inactive Publication Date: 2014-09-03
崔新明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently, there is no cure for the disease, and the condition can suddenly worsen after months of steady treatment
The main means of Western medicine to treat this disease are hormones and immunosuppressants, but hormones have considerable side effects. Long-term and large-scale use of hormones is not conducive to the physical and mental health of patients. Not only that, the reduction and stop of hormones is very likely to lead to aggravation of the disease

Method used

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  • Traditional Chinese medicine oral preparation for treating systemic lupus erythematosus
  • Traditional Chinese medicine oral preparation for treating systemic lupus erythematosus
  • Traditional Chinese medicine oral preparation for treating systemic lupus erythematosus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] The preparation of embodiment 1 Chinese medicine granule

[0015] Weigh 3.0kg of kelp, 3.5kg of verbena, 7.0kg of lotus leaf, 1.3kg of black snake, 5.0kg of Tinglizi and 3.5kg of plantago, add water to decoct twice, and add water for the first time to be 10% of the weight of the medicinal materials. Double the amount, decoct for 2 hours, add water for the second time to be 8 times the weight of the medicinal material, decoct for 1.5 hours, combine the decoctions, concentrate under reduced pressure at 0.08MPa and 70°C until the relative density is 1.15 at 70°C, add 95% ( v / v) Ethanol to make the alcohol content reach 85% (v / v), stir, stand overnight, filter, and concentrate the filtrate under reduced pressure at 0.08MPa and 65°C to a relative density of 1.15g / mL at 65°C Put the extract in a stainless steel plate, vacuum dry (below 60°C) into a dry paste, pulverize, add sucrose powder, make 40-mesh granule powder and pack it, 20g per bag.

Embodiment 2

[0016] The preparation of embodiment 2 Chinese medicine oral liquid

[0017] Weigh 0.26kg of kelp, 0.30kg of verbena, 0.60kg of lotus leaf, 0.10kg of black snake, 0.46kg of Tinglizi and 0.30kg of plantain, add water to decoct twice, and add water for the first time to 10% of the weight of the medicinal materials. Double the amount, decoct for 2 hours, add water for the second time to be 8 times the weight of the medicinal material, decoct for 1.5 hours, combine the decoctions, concentrate under reduced pressure at 0.08MPa and 70°C until the relative density is 1.15 at 70°C, add 95% ( v / v) Ethanol to make the alcohol content reach 75% (v / v), stir, stand overnight, filter, and concentrate the filtrate under reduced pressure at 0.08MPa and 65°C to a relative density of 1.15g / mL at 65°C , add appropriate amount of water and sucrose to prepare oral liquid.

Embodiment 3

[0018] The preparation of embodiment 3 Chinese medicine capsules

[0019] Weigh 2.3kg of kelp, 3.2kg of verbena, 8.0kg of lotus leaf, 0.8kg of black snake, 5.3kg of Tinglizi and 3.2kg of plantain, add water to decoct twice, and add water for the first time to be 10% of the weight of the medicinal materials. Double the amount, decoct for 2 hours, add water for the second time to be 8 times the weight of the medicinal material, decoct for 1.5 hours, combine the decoctions, concentrate under reduced pressure at 0.08MPa and 70°C until the relative density is 1.15 at 70°C, add 95% ( v / v) Ethanol to make the alcohol content reach 85% (v / v), stir, stand overnight, filter, and concentrate the filtrate under reduced pressure at 0.08MPa and 65°C to a relative density of 1.15g / mL at 65°C Put the extract in a stainless steel plate, vacuum dry (below 60°C) into a dry paste, pulverize it, add sucrose powder and dextrin, dry it into 40-mesh granules, add an appropriate amount of talcum powde...

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Abstract

The invention discloses a traditional Chinese medicine oral preparation for treating systemic lupus erythematosus. The composition is prepared from the following Chinese medicinal materials in parts by weight: 23-30 parts of kelp, 26-35 parts of verbena, 50-80 parts of lotus leaves, 8-13 parts of zaocys dhumnade, 40-53 parts of semen lepidii and 26-35 parts of semen plantaginis. The traditional Chinese medicine preparation disclosed by the invention has a certain immune inhibition effect, and can partially replace an immunosuppressive agent, thereby achieving the targets of improving the symptoms of the systemic lupus erythematosus and controlling the disease.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine oral preparation for treating systemic lupus erythematosus. Background technique [0002] Systemic lupus erythematosus (SLE) is a diffuse, systemic autoimmune disease that mainly affects the skin and mucous membranes, skeletal muscles, kidneys, and the central nervous system, and may also affect multiple organs such as the lungs, heart, and blood. And system, showing a variety of clinical manifestations, its etiology and pathogenesis is still unclear. Because of extensive immune damage, multiple organs in various parts of the body can be affected, and the clinical manifestations are diverse. [0003] Currently, there is no cure for the disease, and the condition can suddenly worsen after months of steady treatment. The main means of Western medicine to treat this disease are hormones and immunosuppressants, but hormones have ...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61P37/02A61K35/58
Inventor 刘学键
Owner 崔新明