Cold and cough syrup for children and preparation method thereof

A cold and syrup technology for children, which is applied in the field of medicine, can solve the problems of poor patient acceptance, slow drug absorption, and delay in illness, and achieve good curative effect, convenient transportation, and reduce the burden on patients

Active Publication Date: 2016-04-13
SHAANXI BICON PHARMA GRP HLDG COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In short, traditional Chinese medicine has achieved good curative effect in the treatment of this disease, but there are still some problems: traditional Chinese medicine is mainly based on Chinese patent medicines in the treatment of colds and coughs in children, which not only has large doses, slow drug absorption, and poor acceptance by patients. , not getting better for a long time, it will often delay the disease and make the disease worse

Method used

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  • Cold and cough syrup for children and preparation method thereof
  • Cold and cough syrup for children and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Example 1 A cold and cough syrup for children, in parts by weight (50g per part), its components are: 1.2 parts of Kebiqing, 7 parts of ammonium chloride, 40 parts of Paomazi, 15 parts of raw gypsum, 320 parts of oligosaccharides, sodium benzoate 4 parts, 48 ​​parts of licorice liquid extract, and the balance is water.

[0039] The preparation method of the above-mentioned children's cold and cough syrup, the steps are as follows:

[0040] (1) Pulverize the baomazi and raw gypsum together, and leaching with ethanol solvent with a mass concentration of 30% by percolation method to obtain the filtrate, recover the ethanol, and evaporate and concentrate until the volume (in milliliters) is the weight of the original drug ( 1.8 times that in grams).

[0041] (2) Mix the concentrate obtained in step (1) with liquorice liquid extract, and adjust the pH to 7.2 with sodium hydroxide.

[0042] (3) Boil the oligosaccharides with water, dissolve, filter, and then mix the syrup ...

Embodiment 2

[0045] Example 2 Preparation of cold and cough syrup for children (10g per serving): 1.8 parts of Kebiqing, 13 parts of ammonium chloride, 60 parts of Paomazi, 30 parts of raw gypsum, 420 parts of xylitol, 12 parts of sodium benzoate, 60 parts of licorice liquid extract, The balance is water.

[0046] The preparation method of the above-mentioned children's cold and cough syrup, the steps are as follows:

[0047] (1) Pulverize the baumbazi and raw gypsum together, and leaching with the ethanol solvent with a mass concentration of 80% according to the percolation method to obtain the filtrate, recover the ethanol, and evaporate and concentrate until the volume (in milliliters) is the weight of the original drug ( 2.2 times that in grams).

[0048] (2) Mix the concentrate obtained in step (1) with liquorice liquid extract, and adjust the pH to 8.5 with potassium hydroxide.

[0049] (3) Add water to boil xylitol, dissolve, filter, and then mix the syrup into the mixture obtai...

Embodiment 3

[0053] Example 3 Preparation of cold and cough syrup for children (20g per serving): 1.4 parts of Kebiqing, 8 parts of ammonium chloride, 42 parts of Paomazi, 18 parts of raw gypsum, 360 parts of sucrose, 6 parts of sodium benzoate, 52 parts of licorice liquid extract, and the rest for water.

[0054] The preparation method of the above-mentioned children's cold and cough syrup, the steps are as follows:

[0055] (1) Pulverize the baomazi and raw gypsum together, leaching with ethanol solvent with a mass concentration of 35% according to the percolation method to obtain the filtrate, recover the ethanol, and evaporate and concentrate until the volume (in milliliters) is the weight of the original drug ( 1.9 times that in grams).

[0056] (2) Mix the concentrate obtained in step (1) with liquorice liquid extract, and adjust the pH to 7.5 with ammonia water.

[0057] (3) Add water to boil the sucrose, dissolve, filter, and then mix the syrup into the mixture obtained in step...

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Abstract

The invention discloses a cold and cough syrup for children, which is prepared from the following raw materials in parts by weight: 1.2-1.8 parts of Kebiqing, 7-13 parts of ammonium chloride, 40-60 parts of Paomazi, and 15-30 parts of raw gypsum , 320-420 parts of sugar, 4-12 parts of sodium benzoate, 48-60 parts of licorice liquid extract, and the balance is water. The excellent effect of the present invention is manifested in that the product has good curative effect, quick effect, safety and reliability. The child does not resist and is easy to feed. The process is simple and the production operation is easy. It is convenient for storage and transportation. The source of medicine is easy to obtain, and the cost of medicinal materials is low, which can reduce the burden on patients.

Description

Technical field [0001] The invention is a pharmaceutical technology field, especially involving a child's cold cough syrup and its preparation methods. Background technique [0002] Children's cold and cough are the most common type of diseases in pediatrics. The most seasons are mainly spring and winter. Studies believe that the disease is a type of external disease caused by external evils.Nose, cough, etc., these adverse symptoms have seriously affected the healthy development of children.Pediatrics are in the period of development. Medically, they believe that children's lung qi is weak, skin delicate, unstellically, and the immune system has not yet been perfected.The viscera is tender and weak, and adverse reactions such as nasal congestion, fever, and cough will have a negative effect on the physical and mental of children. [0003] At present, the treatment of children's cold and cough is mainly divided into western medicine treatment and Chinese medicine treatment.At pre...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/63A61P11/00A61P11/14
Inventor 香兴福何宇东陈雪荣
Owner SHAANXI BICON PHARMA GRP HLDG COMPANY
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