A kind of Helicobacter pylori therapeutic agent and preparation method thereof

A Helicobacter pylori and therapeutic agent technology, applied in the field of Helicobacter pylori therapeutic agent and its preparation, to achieve the effects of improved cure rate, inhibitory activity, and short treatment period

Active Publication Date: 2016-12-07
GUIZHOU TELIDA NANO CARBON SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, it has not been reported that nano-carbon powder is directly used in the medical field to treat Helicobacter pylori. Therefore, through long-term exploration and research, this researcher has studied the use of nano-carbon powder in the treatment of Helicobacter pylori and the treatment of Helicobacter pylori. Fields offer a new way

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A Helicobacter pylori therapeutic agent, the therapeutic agent is composed of nano-carbon powder and human body isotonic solution, wherein 96% of the nano-scale in the nano-carbon powder is 4nm, and the dispersibility in water is 99.21%. The mass percentage content is 0.3% in the agent.

[0023] The human body isotonic solution contains 0.85g sodium chloride, 0.035g sodium bicarbonate, and 0.022g potassium chloride in 100ml water.

[0024] The preparation method of the Helicobacter pylori therapeutic agent specifically comprises: mixing the nano-carbon powder with the isotonic solution of the human body according to the above ratio, and adopting a stirrer at a stirring speed of 60 r / min, stirring for 15 minutes, and then mixing the mixed solution Place it in an ultrasonic processor, perform ultrasonic treatment for 20 minutes, and adjust the pH value to 7.8 with sodium bicarbonate-sodium carbonate buffer solution to obtain the therapeutic agent for Helicobacter pylori. ...

Embodiment 2

[0026] A Helicobacter pylori therapeutic agent, the therapeutic agent is composed of nano-carbon powder and human body isotonic solution, wherein 95% of the nano-scale in the nano-carbon powder is 3nm, and the dispersibility in water is 99.21%; The mass percent content is 0.02% in the agent.

[0027] The isotonic solution for human body contains 0.94g sodium chloride, 0.035g sodium bicarbonate and 0.022g potassium chloride in 100ml water.

[0028] The preparation method of the Helicobacter pylori therapeutic agent specifically comprises: mixing the nano-carbon powder with the isotonic solution of the human body according to the above-mentioned ratio, and adopting a stirrer with a stirring speed of 80 r / min, stirring for 20 minutes, and then mixing the mixed solution Place it in an ultrasonic processor, perform ultrasonic treatment for 30 minutes, and adjust the pH value to 9.1 with sodium bicarbonate-sodium carbonate buffer solution to obtain the therapeutic agent for Helicoba...

Embodiment 3

[0030] A Helicobacter pylori therapeutic agent, the therapeutic agent is composed of nano carbon powder and human body isotonic solution, wherein 97% of the nano carbon powder is 2nm, and the dispersibility in water is 99.21%; The mass percent content is 0.5% in the agent.

[0031] The isotonic solution for human body contains 0.9g sodium chloride, 0.033g sodium bicarbonate and 0.0231g potassium chloride in 100ml water.

[0032] The preparation method of the Helicobacter pylori therapeutic agent specifically comprises: mixing the nano carbon powder with the isotonic solution of the human body according to the above ratio, and adopting a stirrer with a stirring speed of 70 r / min, stirring for 17 minutes, and then mixing the mixed solution Place it in an ultrasonic processor, perform ultrasonic treatment for 25 minutes, and adjust the pH value to 8.8 with sodium bicarbonate-sodium carbonate buffer solution to obtain the therapeutic agent for Helicobacter pylori.

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Abstract

The invention relates to the technical field of pylori medication, in particular to a therapeutic agent for Helicobacter pylori and a preparation method thereof, which is composed of nano-carbon powder and human body isotonic solution, and the nano-scale of the nano-carbon powder greater than or equal to 95% is controlled as When it is less than or equal to 4nm level, and the dispersion rate in water is 99.21%, when the concentration of nano-carbon powder in the therapeutic agent is adjusted to 0.02‑0.5%, the nano-carbon powder has a killing effect on Helicobacter pylori, thereby achieving The therapeutic effect of Helicobacter pylori improves the cure rate of Helicobacter pylori patients, and provides a new option for the field of Helicobacter pylori treatment, reducing the cost of Helicobacter pylori treatment.

Description

technical field [0001] The invention relates to the technical field of pylori medication, in particular to a therapeutic agent for Helicobacter pylori and a preparation method thereof. Background technique [0002] Helicobacter pylori infection is the main cause of peptic ulcer and chronic gastritis, and is also closely related to the occurrence of gastric cancer. However, antibiotic-based treatment methods are currently used for ulcers and other diseases, and the adverse reactions are large, and the resistance rate of Helicobacter pylori to antibiotics continues to increase, resulting in an increasing failure rate of eradication therapy. According to relevant data, the radical cure rate is only 20-40%, and this only refers to the situation that there is no recurrence of HP within at least four weeks after treatment. The method of suppressing gastric acid can also heal 80% of ulcers, but it is also temporary, with a recurrence rate of 66% after six months, 80% within one ye...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/44A61P31/04A61P1/04A61K33/14A61K33/00
Inventor 李力
Owner GUIZHOU TELIDA NANO CARBON SCI & TECH
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