Preparation method of spectinomycin hydrochloride injection for dysentery

Abstract

The invention provides a preparation method for a spectinomycin hydrochloride injection for curing diarrhea. The preparation method comprises the following steps: 1) dissolving spectinomycin hydrochloride with water for injection, adding propylene glycol, and performing stirring to dissolve for later use; 2) adding natrium salicylicum and EDTA-2Na into water for injection, stirring to dissolve, and clarifying for later use; 3) mixing liquids obtained in steps 1 and 2, adding a belladonna extract, setting the volume, adjusting the PH value, filtering in a sterile condition, and conveying the liquid to a liquid pot to be packed in a sealing manner to obtain the spectinomycin hydrochloride injection. 1000 ml of spectinomycin hydrochloride injection comprises 4500-5500 million units of spectinomycin hydrochloride, 35-45 g of natrium salicylicum, 4-6 g of belladonna extract, 80-120 ml of propylene glycol and 1-3 g of disodium EDTA (EDTA-2Na), and is set to 1000 ml in volume with water for injection. The traditional Chinese medicine belladonna extract is added into the spectinomycin hydrochloride injection prepared by the method provided by the invention, a new theory for treating livestock and poultry enteritis diarrhea is provided, and the spectinomycin hydrochloride injection can treat both symptoms and root causes of the diarrhea by combining Chinese traditional with western medicine.

Description

technical field

[0001] The invention belongs to the field of veterinary medicine and relates to a preparation method of Spectinomycin Hydrochloride Injection with special effects for dysentery. Background technique

[0002] Spectinomycin is an aminoglycoside antibiotic produced by Streptomyces, used for Gram-negative bacteria and mycoplasma infections. Spectinomycin has the advantages of low toxicity and less toxic and side effects on mammalian liver, lung, kidney, etc. within the effective dose range, and is becoming one of the preferred varieties of veterinary drugs. Studies have shown that Spectinomycin can effectively treat and prevent livestock and poultry diseases caused by Streptococcus, Erysipelas, Staphylococcus aureus, Pasteurella, Escherichia coli, Salmonella and Mycoplasma, especially for the mixed infection of Mycoplasma and Escherichia coli significantly. As a new veterinary antibiotic, spectinomycin has few resistant strains. Spectinomycin is well absorbed ...