IgM (Immune Globulin M) immune turbidimetry test kit

Abstract

The invention discloses an IgM (Immune Globulin M) immune turbidimetry test kit, and belongs to the technical field of clinical in-vitro test reagents. The kit disclosed by the invention comprises a reagent R1, a reagent R2 and a calibration material. The stability and the analysis sensitivity of the kit are effectively improved by adding a certain amount of silicon dioxide-cladded magnetic nano-particles into the reagent R1 and adding a certain amount of bovine serum albumin and Kathon-CG into the reagent R2; the linear range of the kit is also larger; the accuracy of each reagent is high; popularization and application of the kit in markets are facilitated.

Description

technical field

[0001] The invention relates to the technical field of clinical in vitro detection reagents, in particular to an immunoglobulin IgM immunoturbidimetric detection kit. Background technique

[0002] Immunoglobulins are composed of heavy chains and light chains. According to the chemical structure of the constant region of the heavy chain (H chain), the corresponding immunoglobulins are divided into various types, namely immunoglobulin M (IgM), Immunoglobulin D (IgD), Immunoglobulin A (IgA), Immunoglobulin E (IgE), and Immunoglobulin G (IgG).

[0003] Human immunoglobulin M (IgM) exists in human serum, accounting for 5-10% of the total serum immunoglobulins, and the serum concentration is about 1mg / ml. It is mainly synthesized by plasma cells in the spleen. One IgM molecule is composed of 5 single The body is connected into a pentamer through the J chain, which has a high antigen binding value and is also the largest molecular weight among the five classes of i...

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