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A kind of cobalt base alloy and its thermal processing, heat treatment method and application

A heat treatment method and technology of cobalt-based alloys, which are applied in the field of medical materials, can solve problems such as inability to effectively inhibit restenosis in stents, achieve the effects of solving restenosis in stents, reducing or inhibiting restenosis in stents, and reducing the formation of thrombus

Active Publication Date: 2017-11-14
INST OF METAL RESEARCH - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] In view of the above problems, the present invention proposes a cobalt-based alloy and its thermal processing, heat treatment method and application to solve the problem that the existing coronary artery stent cannot effectively inhibit restenosis in the stent

Method used

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  • A kind of cobalt base alloy and its thermal processing, heat treatment method and application
  • A kind of cobalt base alloy and its thermal processing, heat treatment method and application
  • A kind of cobalt base alloy and its thermal processing, heat treatment method and application

Examples

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Embodiment 1

[0059] The content is 20.26 (weight) % of Cr, W: 15.15 (weight) %; Ni: 10.18 (weight) %; Fe: 1.63 %; C: 0.08 (weight) %; Si: 0.58 (weight) %; Mn: 1.15(weight)%; Cu: 4.61(weight)%; the rest is cobalt-based alloy of Co and unavoidable impurities after hot working, specifically:

[0060] Homogenize the cobalt-based alloy at 1200-1250°C for 2-4 hours until the elements in the cobalt-based alloy are fully homogenized;

[0061] The cobalt-based alloy is billet-forged and multi-fired forged into rods and / or blooms, and the final forging temperature is not lower than 1000°C.

[0062] After thermal processing and then heat treatment, specifically:

[0063] Solid solution treatment of the cobalt-based alloy at 1100-1200°C for 1-2 hours until the copper element in the cobalt-based alloy is fully dissolved in the matrix;

[0064] Heat the cobalt-based alloy at 700°C for 2-6 hours until the supersaturated copper is precipitated and a certain amount of copper-rich phase is formed;

[006...

Embodiment 2

[0068] Repeat embodiment 1, following difference is arranged: content is that Cr is 19.87 (weight) %, W: 14.94 (weight) %; Ni: 9.54 (weight) %; Fe: 2.03 (weight) %; C: 0.03 (weight) % ) %; Si: 0.51 (weight) %; Mn: 0.98 (weight) %; Cu: 5.01 (weight) %; the rest is Co and unavoidable impurities Cobalt-based alloy after hot working and heat treatment. See Table 1 for the composition content data of the cobalt-based alloy in Example 2 above, and see Table 2 for the cobalt-based alloy after thermal processing and heat treatment.

Embodiment 3

[0070] Repeat embodiment 1, following difference is arranged: content is that Cr is 19.43 (weight) %, W: 15.59 (weight) %; Ni: 10.90 (weight) %; Fe: 1.98 (weight) %; C: 0.05 (weight) % ) %; Si: 0.80 (weight) %; Mn: 1.85 (weight) %; Cu: 5.45 (weight) %; the rest is Co and unavoidable impurities of cobalt-based alloy after hot working and heat treatment. See Table 1 for the composition content data of the cobalt-based alloy in Example 3, and see Table 2 for the cobalt-based alloy after thermal processing and heat treatment.

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Abstract

The invention provides a cobalt-based alloy. The cobalt-based alloy includes Cu element, wherein the content of Cu element is 4.5-5.5% by weight. The invention also provides a thermal processing method and a heat treatment method of the cobalt-based alloy; and the application of the cobalt-based alloy as a coronary artery stent. The cobalt-based alloy continuously produces trace amounts of copper in the cardiovascular system, which can not only inhibit the hyperplasia, migration and degeneration of arterial smooth muscle after coronary stent implantation, but also effectively reduce the formation of thrombus, thereby reducing or inhibiting coronary artery stent implantation. Function of in-stent restenosis induced after implantation.

Description

technical field [0001] The invention relates to medical materials, in particular to a cobalt-based alloy and its thermal processing, heat treatment method and application. Background technique [0002] Heart disease is one of the primary causes of human health threats, and now about 15 million patients with coronary heart disease worldwide need advanced PTCA (percutaneous transluminal coronary angioplasty, percutaneous coronary angioplasty). PTCA has the advantages of minimal trauma, high efficiency and easy repeatability, so it has become a rapidly developing new method for the treatment of coronary heart disease caused by cardiovascular stenosis. Finely shaped coronary stents are used in PTCA, which are currently mainly processed from medical metal materials such as L605 cobalt-based alloy and 316L stainless steel. [0003] However, a large number of clinical observations show that a certain degree of ISR (in-stentrestenosis, in-stent restenosis) occurs after PTCA, especi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C22C19/07C22F1/10A61L27/04
Inventor 任玲杨柯张书源孙子晴杨春光
Owner INST OF METAL RESEARCH - CHINESE ACAD OF SCI
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