A device for fusion and fixation of pet, ct and mr images of experimental animals

Abstract

The invention discloses a device for PET-CT-MR image fusion and fixation of an experimental animal. The device comprises a fixed frame, a support plate and three sets of positioning rods, wherein a plurality of positioning screws are arranged on the support plate, an elastic rope is arranged on one positioning screw, and fixing ropes and clamp nuts are arranged on the other positioning screws; the three sets of positioning rods have the same number (at least three) of positioning rods; one set of positioning rods is fixed on the fixed frame simultaneously, wherein at least two positioning rods are inclined relative to each other; the positioning rods in each set are filled with PET, CT and MR photographic developers respectively, the positioning rods can be changed to add positioning information to three different image data of the experimental animal, namely PET image data, CT image data and MR image data, and accurate fusion of any more than two scan images is realized by an external feature point extraction method. The device is simple and convenient to operate, can be used repeatedly, guarantees the safety of the animal and workers, meanwhile provides a basis for deep study on image fusion methods and provides more effective, accurate and visual aid for scientific research and clinic and translation thereof.

Description

technical field [0001] The present invention relates to an auxiliary device for the integration of experimental animal fixation and experimental animal image fusion, in particular to a small animal PET, CT and MR image fusion and fixation device, which is used for experimental animal fixation and PET, CT and MR image fusion provides a basis for animal experiments and clinical transformation of image fusion technology. Background technique [0002] Experimental animals, such as rats and rabbits, are widely used as experimental objects in various medical experiments and scientific research, and are one of the more commonly used animal models in modern medical laboratories. However, rodents will resist any unconditioned stimulation, and even cause unnecessary harm to the experimenters, so it is particularly important to fix the experimental animals during the experiment. [0003] In recent years, small animal in vivo imaging has been widely used in small animal disease model r...

AI Technical Summary

Problems solved by technology

Therefore, medical image fusion has become a hot spot in modern medical research, but the image fusion method is still immature, and it cannot be applied to human body for research. Only more data can be obtained through animal experiments to find the optimal image fusion method

[0005] However, at present, there are many kinds of devices used for immobilizing experimental animals, but their functions are single, and their materials are mostly various metal products, which are difficult to be compatible with a variety of imaging equipment. Moreover, there are no fixed identification points on experimental animals or on the immobilizing devices, which cannot realize the immobilization of experimental animals. image fusion

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