X-ray phase contrast imaging system, method and device based on photon counting

Abstract

The invention discloses an X-ray phase contrast imaging system based on photon counting, and also discloses a method and key equipment for realizing X-ray phase contrast imaging by the system. In this system, the X-ray source emits X-rays to the sample on the scanning platform. When the X-ray penetrates the sample, it generates photons that carry the material characteristic information in the spatial position. The photon counting detector counts the photons on the imaging plane to obtain The projection data and energy data of incident photons are transmitted to the three-dimensional reconstruction system; the three-dimensional reconstruction system reconstructs the three-dimensional structure and material composition category inside the sample according to the projection data and energy data, and digitally dyes the components of the sample, so as to determine the material of the sample. ingredients are identified. The invention performs non-destructive detection of weakly absorbing substances through photon counting technology, phase contrast imaging technology and three-dimensional reconstruction technology, and can obtain digital wax blocks with energy discrimination ability and micron-level or nano-level spatial resolution ability.

Description

technical field [0001] The invention relates to an X-ray imaging system, in particular to an X-ray phase-contrast imaging system based on photon counting, and also relates to a method and key equipment for realizing X-ray phase-contrast imaging of the system, belonging to the technical field of radiation imaging. Background technique [0002] The X-ray imaging system detects the internal structure of an object based on the principle that substances absorb X-rays differently, that is, absorption contrast imaging. In practice, traditional X-ray imaging systems can clearly image substances composed of elements with large atomic numbers (such as human bones, etc.), while weakly absorbing substances composed of elements with small atomic numbers (such as carbon, hydrogen, and oxygen) (such as tissue blocks removed during surgery, cell masses taken out by needle biopsy, sediment after centrifugation of body fluids, etc.), etc., are blurred or even impossible to image. When detect...

AI Technical Summary

Problems solved by technology

However, in this technical scheme, the production of the grating is still a bottleneck, which will limit the practical application of the grating phase contrast imaging technology in medicine and industry.

[0006] In addition, most of the existing phase-contrast imaging systems use detectors based on energy integration, resulting in a low utilization rate of X-rays after penetrating the sample.

On the other hand, although the detector based on energy integration can obtain the structural information inside the sample, its ability to obtain the information of the sample material composition is insufficient.

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