54 results about "Photon counting detector" patented technology

A vibrationally enhanced fluorescence microscopy system includes a narrowband pulsed mid-infrared laser configured to excite selected chemical bond vibrations in a sample. A continuous-wave visible laser is coaligned with the mid-infrared laser and configured to induce fluorescence from at least one fluorescent reporter bound to the sample. An external pulse generator temporally synchronizes emission of the mid-infrared pulses with emission of the visible laser. A reflective objective is arranged to deliver the mid-infrared pulses to a focal plane within the sample. A water-immersion objective is coaxially aligned with the reflective objective and arranged to collect the fluorescence from the focal plane. A photon-counting detector is coupled to receive the collected fluorescence. Control electronics are configured to output a vibrational-contrast signal derived from counts produced by the photon-counting detector.

Embodiments relate to a photon counting CT apparatus. An optimum energy band is decided according to a photographing mode, a photographing subject site, or a kind of medical equipment. A photon counting CT apparatus of an embodiment includes a photon counting detector, an acquisition unit, and a decision unit. The photon counting detector detects X-ray photons and acquires energy information. The acquisition unit acquires at least one of information about a photographing mode, information about a photographing subject site, and information about a medical equipment. The decision unit decides at least one of a condition about an energy band of data collected by the photon counting detector and a condition about an energy band of data used in reconstruction processing among data collected by the photon counting detector, based on information acquired by the acquisition unit.

This invention belongs to the field of photon counting detector manufacturing technology, specifically relating to a plasma treatment method for the crystal surface of a photon counting detector and the resulting photon counting detector. The treatment method employs a step-by-step plasma surface modification process. First, the crystal wafer surface is bombarded with plasma generated by the ionization of an inert gas. Then, a secondary bombardment is performed using plasma generated by the ionization of reactive gases such as oxygen and hydrogen. Simultaneously, key process conditions such as process gas flow rate, wafer orientation bias, processing time, cavity vacuum, radio frequency power, plasma parameters, and wafer spacing are systematically controlled. This step-by-step modification process achieves nanoscale modification of the crystal surface, effectively repairing surface damage caused by processing and forming a uniformly distributed surface modification layer. Photon counting detectors fabricated using this method can significantly reduce device leakage current, improve withstand voltage performance, optimize energy resolution, and improve photon counting rate and counting stability.

A system and method for producing a computed tomography (CT) medical image includes receiving x-rays passing through an object with a photon-counting detector system, which includes a plurality of detector pixels configured to generate a photon-counting signal in response to receiving each photon of the x-rays having passed through the object. The method also includes summing a charge associated with each photon received at a given detector pixel of the plurality of pixels to generate a charge integration signal, utilizing the charge integration signal to correct a count of the photon-counting signal for pileup-induced count losses to create a corrected photon-counting signal, and reconstructing an image of the object using the corrected photon-counting signal.

The invention belongs to the technical field of photon detection, and particularly relates to a frequency up-conversion THz wave-based multi-photon detection system and method, and the system comprises a pump light source unit, a beam combiner, a nonlinear crystal, a light splitting unit, a space photon counting detector, a light shaping device, and a controller. According to the technology, THz up-conversion signals are converted from single time domain detection to time and space domain coincidence detection, meanwhile, by means of the spatial resolving power of the multi-photon detector, when time-synchronous fluorescence is achieved, the technology can be combined with the space light gate technology to execute detection in a light gate where the signals are expected to arrive, and therefore fluorescence components are restrained. Finally, effective detection of THz up-conversion signals with spontaneous parametric up-conversion fluorescence can be realized.

The invention discloses a spectrum correction method and system for a photon counting CT detector, and relates to the technical field of medical images.The method comprises the steps that actually-measured film watching data of the detector under a target energy section is obtained; determining an energy section type of a target energy section, and distributing adaptive weights for a pre-constructed detector spectral response model and a pulse accumulation model based on the energy section type; fusing the detector spectral response model and the pulse accumulation model through the adaptive weight to realize coupling of the detector spectral response model and the pulse accumulation model; and carrying out spectrum correction on the photon counting CT detector based on the coupled detector spectrum response model and the pulse accumulation model. The method is helpful for solving the problem that the spectrum of the photon counting CT detector cannot be accurately corrected in the prior art.

The utility model relates to the field of detector chip packaging technology, specifically disclose a kind of chip packaging system of photon counting CT detector, including substrate, substrate is the middle layer of photon counting CT detector, the top of substrate is equipped with top layer sensor by connecting structure, top layer sensor is the top layer (sensor layer) of photon counting CT detector, the bottom of substrate is arranged with multiple ASIC chips by connecting structure, ASIC chip is the bottom layer of photon counting CT detector, the substrate of ASIC chip bottom (upper surface) is simultaneously as the substrate of photon counting CT detector, ASIC chip and photon counting CT detector adopt the same substrate setting, the bottom of substrate is equipped with flexible circuit board. The utility model is provided with a series of structures, quickly export the heat generated by ASIC and transfer to heat sink, realize the accurate temperature control of sensor, to low cost and process difficulty realize four sides can be spliced The photon counting detector that can realize relatively wide z direction coverage.

The application provides a multi-substance density calculation method based on X-ray energy spectrum information, S1, multi-energy spectrum projection data collection: single X-ray exposure is performed on a measured object by using a photon counting detector to obtain projection values of each pixel in each energy interval; S2, multi-substance multi-energy spectrum decomposition model establishment: a nonlinear relationship model is established for multiple substances to be decomposed; S3, substance area density solving: a target function is constructed by the difference between the actual projection values obtained in step S1 and the model calculation values in step S2, and a numerical optimization algorithm is used to solve the target function; S4, quantitative image generation: all pixels are traversed to generate the area density distribution map of each substance. The application obtains multi-energy spectrum information by using a photon counting detector, combines a nonlinear model and an optimization algorithm, realizes synchronous quantitative calculation of the densities of multiple substances, overcomes the defects of limited substance type differentiation and insufficient energy information utilization, and improves the accuracy of substance identification.

The embodiment of the invention discloses a plane X-ray imaging detection method and system. The method comprises: irradiating a plurality of regions of a human body with planar X-rays; acquiring energy projection data of a plurality of energy windows of a plurality of areas of the human body by using a photon counting detector; obtaining image information of a corresponding human body area according to the energy projection data of the plurality of energy windows; and splicing the multiple pieces of image information to obtain a detection image. According to the planar X-ray imaging detection method and system disclosed by the embodiment of the invention, abundant detection information can be conveniently and accurately obtained under the combined action of the planar X-ray and the photon counting detector.

The invention provides a novel CBCT system based on a novel line scanning bulb tube, and belongs to the technical field of X-ray medical image.The novel CBCT system comprises a sampling system and a control system.The sampling system comprises a bulb tube with a light source focus capable of conducting linear track scanning, an energy integration or photon counting detector and a movement rack system; the scanning type anode of the bulb tube can be composed of discrete array light sources and can also be composed of rotary wing anodes, and light source focuses conduct controllable, rapid and repeated scanning or movement in a motion system. Imaging is carried out through controllable light source focus linear track scanning, an imaging method similar to tomosynthesis is achieved at the position of a single bulb tube, and CBCT imaging is achieved under the condition of limited angle sampling through a rotary light source-detector rack combination.

A method for performing detector response correction in an X-ray imaging system having a photon-counting detector is disclosed. The method includes obtaining calibration data stored in a calibration data storage, which is generated during a calibration procedure performed with the X-ray imaging system at a first time. The method also includes acquiring air scan data generated through an air scan performed with the X-ray imaging system at a second time after the first time. The method further includes performing, with the X-ray imaging system, an object scan on an imaging object at a third time to generate object scan data. The third time is after the second time. The method further includes performing, using the generated object scan data, detector response correction based on the acquired air scan data and the obtained calibration data, and reconstructing, based on the performed detector response correction, an image of the imaging object.

The application provides a flow analysis system signal processing method and device, equipment and a storage medium, and the method comprises the following steps: acquiring a detection signal of scattered light emitted by a detected particle under laser irradiation by a scattered light detector, to obtain an electric signal; analyzing the electric signal, excluding interference through a preset threshold, to obtain a starting time and an ending time of the detected particle passing through a detection area; acquiring a detection signal of fluorescence emitted by the detected particle under laser irradiation by a fluorescence detector of each fluorescence channel, to obtain a light pulse signal; recording generation conditions of the light pulse signal in the starting and ending intervals and analyzing to obtain a peak value and an area of the channel as a detection result of the channel signal. For the detection result of the photon counting detector, the method provided by the application can simply and quickly extract the area and height parameters of the event signal, can be compared with the detection and processing result of the traditional flow cytometer using an analog detector, and the method has strong compatibility.

To reduce a data amount of correction data acquired by calibration in a calibration device, method and program for a photon counting type detector.SOLUTION: To acquire calibration data of a photon counting type detector composed of a plurality of detection elements for outputting a detection signal corresponding to photon energy of incident radiation. The processor is configured to acquire a plurality of detection signals output from a plurality of detection elements of the photon counting detector according to a predetermined acquisition condition, derive a difference signal indicating a difference between at least one representative detection signal representing the plurality of detection signals and the plurality of detection signals, and store the at least one representative detection signal and the difference signal as calibration data according to the acquisition condition.SELECTED DRAWING: Figure 5

A processor acquires projection data for multiple energy bins by detecting radiation transmitted through a subject using a photon-counting detector. It identifies first matching calibration data corresponding to the energy spectrum of the projection data from among multiple pieces of calibration data for material discrimination, each representing energy spectra of combinations of predefined calibration members. The processor then determines the presence or absence of a singularity in the attenuation coefficient based on differences, for each energy bin, between attenuation coefficients from the projection data and the first calibration data. If a singularity is determined to be present, the processor specifies second matching calibration data, selected from among the plurality of calibration data, based on the energy spectrum of the projection data at the higher- or lower-energy side of the singularity.

1. Name of the product in this design: Photon Counting Detector Module. 2. Intended use of this design: for use in medical imaging equipment - X-ray computed tomography. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

This invention discloses a dynamic control method for adaptive bias voltage in the energy region of a CZT photon counting detector, belonging to the field of radiation detection and photon counting control technology. The method acquires energy events of incident photons within a fast sliding time window and forms an energy spectrum histogram, extracting energy region composition information and flux status information for low, medium, and high energy regions. Within a slow sliding time window, it acquires count rate change information, energy peak drift information, pulse tail change information, leakage current status information, temperature status information, and current operating bias voltage information. Based on the energy region composition information, flux status information, flux change trend, and current operating bias voltage information, it matches them with a preset energy region bias voltage mapping relationship to generate candidate operating bias voltages. A polarization risk index is constructed based on count rate change, energy peak drift, pulse tail change, leakage current status, and temperature status, and a bias voltage compensation amount is generated based on the level and trend of the polarization risk index.

The present application relates to the field of air tightness detection, in particular to a kind of air tightness in-situ detection method of detector interface in ICP-OES system, including in the stable stage of ICP-OES system plasma torch flame and no sample introduction carrier gas, control DMD micromirror array switches between full open state and full off state;The photon counting value of MCP single-photon counting detector is recorded in the two states of DMD micromirror array respectively, and the difference of the photon counting value in the two states is used as effective light flux reference;Periodically measure the difference of photon number, and calculate the decay rate according to the difference of photon number, when the decay rate exceeds the preset threshold, determine that the interface air tightness is abnormal.The present application solves the pain points of offline, qualitative, lag in the prior art, guarantees the detection accuracy and operation stability of ICP-OES system, reduces operating cost.

Analytical device and analytical process, set up for internal referencing which is independent from the kind of optical response of a sample. The device comprises a light source directed to a sample location, a photon counting detector set up to receive light emanating from the sample location and to generate photon counts, an integrator coupled to the detector and set up to receive photon counts from the detector and to integrate the photon counts over an integration time to generate integrated measurement signals, and coupled to the integrator an analogue-to-digital converter set up to receive the integrated measurement signals and to generate digital measurement signals for each of the integrated measurement signals and to deliver the digital measurement signals to a control unit, which is set up for deconvolution of the digital measurement signals in order to determine correction functions, wherein the control unit is set up to convert separately determined digital measurement signals which are determined for samples in dependence on the correction functions.

The invention discloses a system for evaluating coronary artery stenosis through a photon CT low-dose low-concentration contrast agent scheme, and belongs to the field of medical images. The invention discloses a system for evaluating coronary artery stenosis by using a photon CT low-dose low-concentration contrast agent scheme. The system comprises a multi-energy spectrum data acquisition unit, a data preprocessing unit, an image generation unit, an image segmentation unit, a plaque analysis unit and a stenosis detection unit. The problems that in existing coronary artery CT examination, the radiation dosage is high, the contrast agent dosage is large, and the diagnosis process highly depends on physician experience, so that efficiency is low, and subjectivity is high are solved, the photon counting CT detector and optimized low-dosage scanning parameters are adopted, the deep learning algorithm and the multi-material decomposition technology are combined, and the CT examination efficiency is improved. High-quality coronary artery imaging and accurate stenosis evaluation under the conditions of low dosage and low concentration of contrast agents are realized, radiation exposure and contrast agent related risks of patients are remarkably reduced, and accuracy and reliability of coronary artery stenosis detection and plaque component analysis are improved.

To provide a control device, a method, and a program for a radiation imaging apparatus, capable of appropriately setting a parameter in imaging according to a region of a subject.SOLUTION: When controlling a radiation imaging apparatus including a photon counting type detector that detects radiation emitted from a radiation source and transmitted through a subject on a bed and outputs a detection signal corresponding to photon energy of the radiation, a highly sensitive site having relatively higher sensitivity to the radiation in the subject than other sites is specified based on an optical image acquired by a camera that acquires the optical image of the subject, and different parameters related to a radiation dose to be emitted to the subject are set for the highly sensitive site and the other sites.SELECTED DRAWING: Figure 3

The embodiment of the invention provides a photon counting detector, and the detector comprises a scintillation crystal array which is used for converting X-rays into fluorescence; the photoelectric converter is used for converting the fluorescence into an electronic signal; the photon counting circuit is used for processing the electronic signal to obtain photon counting data; the control reading circuit is used for reading the photon counting data and transmitting the photon counting data to the external reading circuit; the scintillation crystal array is made of scintillation crystal materials, and the luminescence decay time of the scintillation crystal materials is within 25 ns.

The application discloses a system for testing packaging effect of a photon counting detector. The photon counting detector comprises a photon detection element, an adapter plate and a photon counting integrated circuit board. A first connecting circuit is arranged on the photon detection element and connected with a pad on the photon detection element, and a second connecting circuit is arranged on the photon counting integrated circuit board and connected with a pad on the photon counting integrated circuit board. The first connecting circuit is connected with a pad on a first surface of the adapter plate, the second connecting circuit is connected with a pad on a second surface of the adapter plate, the pad on the first surface of the adapter plate is electrically connected with the pad on the second surface, and the first connecting circuit, the second connecting circuit and the pads of the adapter plate connecting the first connecting circuit and the second connecting circuit form an electrical connection path. A test unit is connected with the electrical connection path, used for detecting an electrical signal of the electrical connection path, judging a bonding state of the pads in the electrical connection path according to the electrical signal, and thus obtaining a process quality of the photon counting detector.

The present description relates to a photon-counting detector comprising a plurality of electrodes each connected to a readout circuit (RDc). Each readout circuit (RDc) generates an active detection signal (evt) when charges are collected by the electrode to which this circuit is connected. Each readout circuit, referred to as the central circuit (RDc), carries out charge sharing correction by exchanging signals with readout circuits, referred to as circuits adjacent to the central circuit (RDc), connected to electrodes adjacent to the electrode to which the central circuit is connected, referred to as the central electrode. Each central circuit (RDc) selectively activates and deactivates (CSC-EN; EN) the charge sharing correction that it carries out on the basis of at least the detection signal (evt) that it generates.

The invention relates to the field of airtightness detection, in particular to an in-situ airtightness detection method for a detector interface in an ICP-OES (Inductively Coupled Plasma Optical Emission Spectrometer) system, which comprises the following steps of: controlling a DMD (Digital Micromirror Device) micromirror array to be switched between a fully-open state and a fully-closed state in a carrier gas stable stage when the ICP-OES system ignites plasma torch flame and no sample is fed; respectively recording photon counting values of the MCP single photon counting detector when the DMD micromirror array is in two states, and taking a difference value of the photon counting values in the two states as an effective luminous flux reference; and periodically measuring a photon number difference value, calculating an attenuation rate according to the photon number difference value, and when the attenuation rate exceeds a preset threshold value, judging that the air tightness of the interface is abnormal. The method solves the problems of offline, qualitative and lagged pain points in the prior art, guarantees the detection precision and operation stability of the ICP-OES system, and reduces the operation cost.

The application discloses an X-ray diffraction-based photon counting detector energy response calibration system, comprising an X-ray source, a pencil collimator for forming pencil X-rays from the X-rays, a crystal sample, diffraction X-rays generated after the pencil X-rays irradiate the crystal sample, a transmission blocker for blocking transmission X-rays formed after the pencil X-rays transmit through the crystal sample, a photon counting detector for detecting characteristic diffraction energy of the diffraction X-rays, and a controller for adjusting X-ray source parameters to screen preset characteristic diffraction energy reaching the photon counting detector, and controlling the photon counting detector to translate so that the photon counting detector and diffraction angles of the diffraction X-rays continuously change within a preset angle range, measure detector energy response of the photon counting detector at each position under the preset characteristic diffraction energy, and perform photon counting detector energy response calibration. The system does not need to rely on simulation modeling and mathematical parameter models, and can directly perform energy response calibration of the detector.

The invention belongs to the technical field of optical precision measurement, and discloses a vacuum ultraviolet spectrophotometric measurement method based on a photon counting method, which comprises the following steps: in a sample-free state, setting a polarization state of incident light according to a measurement task, and aiming at each wavelength point in a preset measurement wave band, calculating the polarization state of the incident light; collecting an initial dark count and an initial baseline count corresponding to the wavelength point; on the basis of the initial dark count and the initial baseline count, through signal-to-noise ratio optimization, respectively calibrating the optimal working voltage of the photon counting detector under each wavelength point and a double-discrimination threshold value for separating noise; under the same polarization state, dark counts and reference counts corresponding to the wavelength points are collected based on the optimal working voltages and the double discrimination thresholds corresponding to the wavelength points; the problems that in vacuum ultraviolet band measurement in the prior art, due to the fact that detection parameters cannot be dynamically optimized in the whole spectrum band, the signal-to-noise ratio of a system is low, and the measurement precision is insufficient are effectively solved.

The application belongs to the technical field of biomedical detection, and discloses a Raman spectrum analysis device for quantitative detection of blood tumor markers, which comprises a blood collection and centrifugal unit with an adaptive load adjustment mechanism, which is used for real-time monitoring of blood density and composition, and automatic adjustment of centrifugal force and time parameters according to the blood density and composition; a fiber Raman spectrometer equipped with an automatic wavelength calibration system, wherein an ultrafast laser pulse emitter and a high-sensitivity photon counting detector are integrated on the fiber Raman spectrometer; the application enhances the Raman scattering signal by adopting a quantum entangled light source and a nonlinear optical crystal, and can significantly improve the detection capability of low-concentration tumor markers. This improvement enables the device to accurately detect the presence of tumor markers in the early stage of cancer, providing strong support for early treatment of patients.

The application relates to a photon counting detector and a CT imaging system. The photon counting detector comprises a detection medium, a signal processing chip and a conductive layer. The detection medium comprises a plurality of pixels, each of which is used for converting incident X-ray radiation into an electrical signal. The signal processing chip is used for processing the electrical signal. One end of the conductive layer is connected to the pixels of the detection medium, and the other end is connected to the pins of the signal processing chip. The conductive layer is a flexible conductive layer. By setting the conductive layer as a flexible conductive layer, the advantages of the two materials can be considered. The electrical conductivity can be used to realize the interconnection of the high-density pixel detection medium and the signal processing chip, and the flexibility of the material can be used to cope with the internal stress introduced by environmental changes, thereby improving the reliability of the photon counting detector module.

A method according to an embodiment includes: acquiring calibration data that is generated during a calibration procedure executed at a first time using an X-ray imaging system (10) having a photon counting detector (12), and is stored in a calibration data storage unit (320, 41); acquiring air scan data generated by an air scan executed at a second time after the first time using the X-ray imaging system (10); generating object scan data by executing, on an imaging object (P), an object scan at a third time after the second time using the X-ray imaging system (10); executing detector response correction on the basis of the air scan data and the calibration data using the object scan data; and reconstructing an image of the imaging object (P) on the basis of the detector response correction.

This disclosure relates to the field of X-ray based medical imaging technology, providing a method, device, and CT scanning imaging system for spectral CT imaging, which may improve the efficiency of reconstructed images. In this disclosure, after obtaining multiple data frames collected by the detector, each data frame is cached in energy segments and stored in memory; Read the data frames required for image reconstruction from memory or disk; Obtain reconstructed images using the read data frames.