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Medicament for treating prosopalgia

A technology for trigeminal neuralgia and drugs, applied in the field of traditional Chinese medicine, can solve problems such as long treatment time, damage to cranial nerves or brain tissue, blindness, etc., and achieve the effects of no toxic side effects, low treatment costs, and pain relief.

Inactive Publication Date: 2015-05-20
QINGDAO CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Not only the treatment time is long, but the treatment cost is also relatively high; some may even cause damage to cranial nerves or brain tissue, and there are also serious sequelae such as blindness, cerebral hemorrhage, and facial paralysis.
The side effects of western medicine are relatively obvious. Some patients have dizziness, fatigue, nausea and vomiting, leukopenia, rash and other adverse reactions after use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0030] The present invention also provides a preparation method of the above-mentioned medicine, specifically comprising:

[0031] The first step is to select codonopsis, forsythia, peacock grass, angelica dahurica, goose not eating grass, cinnamon twigs, rehmannia glutinosa, rhizome root, goosegrass, rhubarb rhubarb, cloud moss, scrophulariaceae, magnolia and licorice, and grind them separately into powder, put it into a blender by weight, mix and stir evenly, add water to decoct twice, add water for the first time to be 10 times the mass of the raw material drug mixture obtained in this step, decoct for 2 hours, add water for the second time to obtain the mass of the raw material drug mixture 8 times the amount, decocted for 1.5h, combined the decoction, concentrated under reduced pressure at 0.08MPa and 70°C to a relative density of 1.15 at 70°C, added 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stirring, standing overnight, filtering, and concentrating ...

Embodiment 1

[0083] Embodiment 1 oral liquid 1

[0084] Take 50g of Codonopsis, 30g of Forsythia, 25g of Peacock Grass, 35g of Angelica dahurica, 15g of Goose Bubiograss, 25g of Guizhi, 30g of Rehmannia glutinosa, 10g of Dixie root, 25g of goosegrass, 15g of rhubarb, 20g of Carex scrophulariae, and Scrophulariaceae 35g, 30g magnolia and 15g licorice, crushed into powder respectively, put into a blender, mix and stir evenly, add water to decoct twice, add 3.6kg of water for the first time, decoct for 2h, add 3kg of water for the second time, decoct for 1.5h, combine Decoction, 0.08MPa, concentrated under reduced pressure at 70°C to a relative density of 1.15 at 70°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, stand overnight, filter , the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to a relative density of 1.15g / mL at 65°C to obtain the first extract. 20g of madder, 25g of Puhuang, 20g of canopy grass, 20g of sweet potato vine, dandelio...

Embodiment 2

[0090] Embodiment 2 oral liquid 2

[0091] Take 48g of Codonopsis, 28g of Forsythia, 23g of Peacock Grass, 33g of Angelica dahurica, 13g of Goose Bubiograss, 23g of Guizhi, 28g of Rehmannia glutinosa, 8g of Dixie root, 23g of goosegrass, 13g of rhubarb, 18g of Carex scrophulariae, and Scrophulariaceae 33g, 28g magnolia and 13g licorice, crushed into powder respectively, put into a blender, mix and stir evenly, add water to decoct twice, add 3.6kg of water for the first time, decoct for 2h, add 3kg of water for the second time, decoct for 1.5h, combine Decoction, 0.08MPa, concentrated under reduced pressure at 70°C to a relative density of 1.15 at 70°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, stand overnight, filter , the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to a relative density of 1.15g / mL at 65°C to obtain the first extract. 18g of madder, 23g of Puhuang, 18g of canopy grass, 18g of sweet potato vine, and dande...

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PUM

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Abstract

The invention provides a medicament for treating prosopalgia. The medicament comprises a medicine for oral use and an external medicine, wherein the medicine for oral use comprises the following active pharmaceutical ingredients: radix codonopsis, fructus forsythiae, radix rubiae, pollen typhae, french marigold, radix angelicae dahuricae, Centipeda minima, bitter fleabane, ficus tikoua, dandelion, radix sophorae flavescentis, cassia twig, prepared rehmannia root, Melastoma dodecandrum Lour, rheum rhaponticum, sedge, myrrh, radix scrophulariae, flosmagnoliae and radix glycyrrhizae; the external medicine comprises the following active pharmaceutical ingredients: burmann cinnamon bark, Hibiscus rosa-sinensis, filifolium sibiricum, rice galingale herb, radix paeoniae alba, earthworms, herba ephedrae, swertia mileensis, cortex eucommiae, Rhaphidophora peepla, corydalis amabilis, fructusarctii, and radix glycyrrhizae. Through internal and external treatment, on one hand, channel qi is dredged, qi arrives to achieve the efficacy of relieving pain, on the other hand, the pain is relieved through dispersion of potency to alleviate pain, satisfactory clinical treatment effect can be more easily obtained as a whole, and compared with the traditional therapy, the treatment cost is less, and no toxic and side effects exist.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating trigeminal neuralgia. Background technique [0002] Trigeminal neuralgia is relatively common clinically, and refers to paroxysmal, transient severe pain in the distribution area of ​​the trigeminal nerve. Each attack lasts from seconds to minutes. During the pain attack period, severe cases can reach dozens of times a day. The pain is like electric shock, burning, knife cutting, and acupuncture. Primary disease is prone to occur in middle-aged and elderly people, and 70% to 80% of patients are over 40 years old. There are many treatment methods for trigeminal neuralgia, from simple oral drug therapy, physical therapy, to various drug injection sealing therapy, surgical cutting, avulsion, radiofrequency temperature-controlled thermocoagulation, microvascular decompression, etc. The commonly used clinical methods for the treatment of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P25/02
Inventor 孙锋相波房雷袁海成吴娴娴
Owner QINGDAO CENT HOSPITAL
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