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Medicines used to treat trigeminal neuralgia

A technology of trigeminal neuralgia and medicine, which is applied in the field of traditional Chinese medicine, can solve problems such as long treatment time, leukopenia, and paralysis, and achieve the effect of less treatment cost, no toxic side effects, and pain relief

Inactive Publication Date: 2016-02-10
QINGDAO CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Not only the treatment time is long, but the treatment cost is also relatively high; some may even cause damage to cranial nerves or brain tissue, and there are also serious sequelae such as blindness, cerebral hemorrhage, and facial paralysis.
The side effects of western medicine are relatively obvious. Some patients have dizziness, fatigue, nausea and vomiting, leukopenia, rash and other adverse reactions after use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0030] The present invention also provides a preparation method of the above-mentioned medicine, which specifically includes:

[0031] The first step is to select Codonopsis pilosula, Forsythia, Malachite, Angelica Radix, Goose does not eat grass, Cinnamon twig, Rehmannia glutinosa, Radix Radix et Rhizoma Root, Beef tendon grass, Rhubarb Radix, Cloudgrass, Scrophularia Radix, Xinyi and Licorice, and pulverize them respectively. Make powder, put it into a mixer by weight, mix and stir evenly, add water to decoct twice, the first time adding water is 10 times the mass of the crude drug mixture obtained in this step, decocted for 2 hours, and the second time adding water is the quality of the crude drug mixture 8 times the amount, decoct for 1.5h, combine the decoction, concentrate under reduced pressure at 0.08MPa and 70°C to a relative density of 1.15 at 70°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v) / v), stirred, left standing overnight, filtered, the ...

Embodiment 1

[0083] Example 1 Oral Liquid 1

[0084] Take Codonopsis 50g, Forsythia 30g, Malachite 25g, Angelica 35g, Goosebum 15g, Cinnamomum twig 25g, Rehmannia glutinosa 30g, Radix Radix Root 10g, oxtenoid grass 25g, Rhubarb 15g, Cloudmoss 20g, Scrophulariaceae 35g, 30g of Xinyi and 15g of licorice, pulverized into powders respectively, put into a blender, mixed and stirred evenly, add water and decocted twice, add 3.6kg of water for the first time, decocted for 2h, add 3kg of water for the second time, decocted for 1.5h, and combine Decoction, the relative density is 1.15 when concentrated under reduced pressure at 70°C under 0.08MPa, 70°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, let stand overnight, filter , the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to a relative density of 1.15g / mL at 65°C, to obtain the first extract, 20g of madder, 25g of Puhuang, 20g of Tianpeng grass, 20g of sweet potato vine, dandelion 25g, 20g of ...

Embodiment 2

[0090] Example 2 Oral Liquid 2

[0091] Take Codonopsis 48g, Forsythia 28g, Malachite 23g, Angelica 33g, Goosebum 13g, Cinnamon stick 23g, Rehmannia glutinosa 28g, Diwali root 8g, Beef tendon grass 23g, Rhubarb 13g, Cloudmoss 18g, Scrophulariaceae 33g, 28g of Xinyi and 13g of licorice, pulverized into powders respectively, put into a blender, mixed and stirred evenly, add water for two times, add 3.6kg of water for the first time, boil for 2 hours, add 3kg of water for the second time, boil for 1.5 hours, and combine Decoction, the relative density is 1.15 when concentrated under reduced pressure at 70°C under 0.08MPa, 70°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, let stand overnight, filter , the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to a relative density of 1.15g / mL at 65°C, and the first extract was obtained. 23g, 18g of Sophora flavescens, and 18g of myrrh were pulverized into powders, put into a mixer by wei...

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PUM

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Abstract

The invention provides a medicament for treating prosopalgia. The medicament comprises a medicine for oral use and an external medicine, wherein the medicine for oral use comprises the following active pharmaceutical ingredients: radix codonopsis, fructus forsythiae, radix rubiae, pollen typhae, french marigold, radix angelicae dahuricae, Centipeda minima, bitter fleabane, ficus tikoua, dandelion, radix sophorae flavescentis, cassia twig, prepared rehmannia root, Melastoma dodecandrum Lour, rheum rhaponticum, sedge, myrrh, radix scrophulariae, flosmagnoliae and radix glycyrrhizae; the external medicine comprises the following active pharmaceutical ingredients: burmann cinnamon bark, Hibiscus rosa-sinensis, filifolium sibiricum, rice galingale herb, radix paeoniae alba, earthworms, herba ephedrae, swertia mileensis, cortex eucommiae, Rhaphidophora peepla, corydalis amabilis, fructusarctii, and radix glycyrrhizae. Through internal and external treatment, on one hand, channel qi is dredged, qi arrives to achieve the efficacy of relieving pain, on the other hand, the pain is relieved through dispersion of potency to alleviate pain, satisfactory clinical treatment effect can be more easily obtained as a whole, and compared with the traditional therapy, the treatment cost is less, and no toxic and side effects exist.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating trigeminal neuralgia. Background technique [0002] Trigeminal neuralgia is relatively common clinically, and refers to the episodic, transient severe pain in the distribution area of ​​the trigeminal nerve. Each attack lasts from a few seconds to a few minutes. During the pain attack period, it can reach dozens of times a day in severe cases. The pain is like electric shock, burning, knife cutting and acupuncture. The disease occurs in middle-aged and elderly people, and 70% to 80% of the patients are over 40 years old. There are many treatment methods for trigeminal neuralgia, from simple oral drug therapy, physical therapy, to various drug injection and sealing therapy, as well as surgical amputation, avulsion, radiofrequency temperature-controlled thermocoagulation, and microvascular decompression. Common clinical methods for the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P25/02
Inventor 孙锋相波房雷袁海成吴娴娴
Owner QINGDAO CENT HOSPITAL
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